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Analyze gene-set  Analyze locus  Analyze orthologous gene-set 


GREAM enables user to analyze repeat element distribution using three different options

  1. Analyze gene-set
  2. Analyze locus
  3. Analyze orthologous gene-set
  4. GREAM processing time based on size of gene-set and neighborhood region

Analyze gene-set

Figure 1: Input parameters of 'analyze gene-set' option  Top


Figure 2: Analysis using sample gene-set  Top


Figure 3a: Job status page showing processing status of the input and link to the output page  Top


Figure 3a:Result of gene-set analysis (Table showing list of repetitive elements found in neighborhood region of one or more genes from given set along with statistical significance for their over-representation.)  Top


Figure 4a: Visualizing distribution of specific repeat elements across neighborhood of given gene set  Top

Figure 4b: Snapshot of repeat element distribution  Top


Figure 5: Gene-wise report for given input set  Top


Figure 6: Page showing information about specific repeat element  Top


Figure 6: Gene ontology analysis of genes having specific repeat elements in thier neighborhood  Top



Analyze locus

Figure 7: Input parameters of 'analyze locus' option  Top

Figure 8: Result of locus analysis  Top

Analyze orthologous gene-set

Figure 9: Input parameters of 'analyze orthologous gene-set' option  Top

Figure 10: Analysis using sample gene-set  Top

Figure 11: Result of orthologous gene-set analysis  Top

Figure 12: Result of orthologous gene-set analysis [ A. Shows frequency of occurrance of repeat elements in submitted rat gene-set with statistical significance, B. Shows frequency of occurrance of repeat elements in the mouse orthologous gene-set with statistical significance, C. Shows frequency of occurance of repeat elements in the human orthologous gene-set with statistical significance and D. Shows repeat element commonly over-represented in the neighbouhood region of human, mouse and rat orthologous gene-sets. ] Top



GREAM processing time based on size of gene-set and neighborhood region around transcription start site

Based on 'gene counts'
Gene-set size
Region10205070100
10KB717446083
20KB717456084
50KB717456084
100KB817456185
200KB718456184
500KB717456184
1MB7*17*46*62*84*
1.5MB7*17*46*63*85*
2MB7*17*46*64*85*
2.5MB7*17*47*65*85*
3MB6*17*47*66*85*
Time taken by GREAM in seconds
Based on 'repeat counts'
Gene-set size
Region10205070100
10KB7225681*117*
20KB18277096*136*
50KB1843180261*386*
100KB2896672994*1499*
200KB7334030084476*6785*
500KB48925253240048357*73662*
1MB941*4901*62701*93575*142530*
1.5MB1431*7474*95886*143105*217980*
2MB1921*10048*129071*192635*293430*
2.5MB2411*12621*162256*242165*368880*
3MB2901*15195*195441*291695*444330*
Time taken by GREAM in seconds

* Time in seconds estimated by simple linear regression method (soon will be replced by actual time)