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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for HDAC5 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000122
negative regulation of transcription from RNA polymerase II promoter
IDA
GO:0000122
negative regulation of transcription from RNA polymerase II promoter
IMP
GO:0006325
chromatin organization
TAS
GO:0006338
chromatin remodeling
TAS
GO:0006342
chromatin silencing
TAS
GO:0006954
inflammatory response
TAS
GO:0010830
regulation of myotube differentiation
ISS
GO:0010832
negative regulation of myotube differentiation
IMP
GO:0016568
chromatin modification
TAS
GO:0016575
histone deacetylation
IDA
GO:0016575
histone deacetylation
TAS
GO:0030183
B cell differentiation
TAS
GO:0032869
cellular response to insulin stimulus
NAS
GO:0042113
B cell activation
TAS
GO:0043393
regulation of protein binding
IMP
GO:0045892
negative regulation of transcription, DNA-dependent
TAS
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IMP
GO:0051091
positive regulation of sequence-specific DNA binding transcription factor activity
IMP
GO:0090051
negative regulation of cell migration involved in sprouting angiogenesis
IMP
cellular_component
GO:0000118
histone deacetylase complex
TAS
GO:0005634
nucleus
IDA
GO:0005737
cytoplasm
IDA
molecular_function
GO:0004407
histone deacetylase activity
IDA
GO:0005080
protein kinase C binding
IPI
GO:0005515
protein binding
IPI
GO:0008134
transcription factor binding
IPI
GO:0016787
hydrolase activity
IEA
GO:0032041
NAD-dependent histone deacetylase activity (H3-K14 specific)
IEA
GO:0034739
histone deacetylase activity (H3-K16 specific)
IEA
GO:0044212
transcription regulatory region DNA binding
IDA
GO:0046969
NAD-dependent histone deacetylase activity (H3-K9 specific)
IEA
GO:0046970
NAD-dependent histone deacetylase activity (H4-K16 specific)
IEA
GO:0070491
repressing transcription factor binding
IPI
Protein-protein interaction details for HDAC5 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
ZBTB16
Reconstituted Complex
physical
15467736
ZBTB16
Affinity Capture-Western
physical
15467736
YWHAQ
Affinity Capture-Western
physical
15367659
PRKD1
Affinity Capture-Western
physical
15367659
YWHAQ
Two-hybrid
physical
15367659
CTBP1
Reconstituted Complex
physical
11022042
NRIP1
Reconstituted Complex
physical
15060175
NRIP1
Co-localization
physical
15060175
GATA1
Affinity Capture-Western
physical
14668799
GATA1
Affinity Capture-Western
physical
14668799
GATA1
Reconstituted Complex
physical
14668799
MEF2D
Affinity Capture-Western
physical
12896970
GATA2
Affinity Capture-Western
physical
11567998
TAB2
Reconstituted Complex
physical
12150997
HDAC3
Affinity Capture-Western
physical
10220385
HDAC3
Affinity Capture-Western
physical
11804585
NCOR1
Affinity Capture-Western
physical
11931768
TBL1X
Affinity Capture-Western
physical
11931768
HDAC3
Affinity Capture-Western
physical
11931768
GPS2
Affinity Capture-Western
physical
11931768
BCL6
Affinity Capture-Western
physical
11929873
BCL6
Reconstituted Complex
physical
11929873
ZBTB16
Reconstituted Complex
physical
11929873
IKZF1
Affinity Capture-Western
physical
12015313
IKZF3
Affinity Capture-Western
physical
12015313
IKZF2
Affinity Capture-Western
physical
12015313
IKZF4
Affinity Capture-Western
physical
12015313
IKZF1
Affinity Capture-Western
physical
12015313
NCOR2
Two-hybrid
physical
10640275
NCOR1
Reconstituted Complex
physical
10640275
NCOR2
Reconstituted Complex
physical
10640275
MEF2A
Affinity Capture-Western
physical
10748098
MEF2A
Reconstituted Complex
physical
10748098
YWHAB
Affinity Capture-Western
physical
10869435
YWHAE
Affinity Capture-Western
physical
10869435
HDAC3
Affinity Capture-Western
physical
10869435
CBX5
Reconstituted Complex
physical
12242305
CBX5
Affinity Capture-Western
physical
12242305
SUV39H1
Affinity Capture-Western
physical
12242305
EEF1G
Two-hybrid
physical
16169070
GABARAP
Two-hybrid
physical
16169070
HR
Affinity Capture-Western
physical
11641275
PKN2
Affinity Capture-MS
physical
20188095
PKN1
Biochemical Activity
physical
20188095
PKN2
Biochemical Activity
physical
20188095
RUNX2
Affinity Capture-Western
physical
16613856
HIF1A
Affinity Capture-Western
physical
19071119
HIF1A
Reconstituted Complex
physical
19071119
ESR1
Reconstituted Complex
physical
19893013
GATA3
Affinity Capture-Western
physical
17075044
GATA3
Affinity Capture-Western
physical
17075044
SMAD7
Affinity Capture-Western
physical
15831498
HOXC11
Two-hybrid
physical
20211142
MAFF
Two-hybrid
physical
20211142
YWHAG
Affinity Capture-Western
physical
18951085
REST
Affinity Capture-Western
physical
17011572
REST
Affinity Capture-Western
physical
17011572
SIN3A
Affinity Capture-Western
physical
17011572
MARK3
Affinity Capture-Western
physical
16980613
KLF4
Affinity Capture-Western
physical
18768922
KLF4
Affinity Capture-Western
physical
18768922
YY1
Affinity Capture-Western
physical
16822951
YY1
Affinity Capture-Western
physical
16822951
CAMK1
Affinity Capture-Western
physical
16767219
CAMTA2
Affinity Capture-Western
physical
16678093
YY1
Affinity Capture-Western
physical
18632988
GCM1
Affinity Capture-Western
physical
16528103
GCM1
Affinity Capture-Western
physical
16528103
NUP214
Affinity Capture-Western
physical
16356933
GNB1
Affinity Capture-Western
physical
16221676
GNB1
Reconstituted Complex
physical
16221676
MEF2A
Reconstituted Complex
physical
12626519
UBE2I
Two-hybrid
physical
16166628
SMAD3
Affinity Capture-Western
physical
15990875
SMAD3
Reconstituted Complex
physical
15990875
RUNX2
Affinity Capture-Western
physical
15990875
RUNX2
Affinity Capture-Western
physical
15990875
RFXANK
Reconstituted Complex
physical
15964851
ANKRA2
Reconstituted Complex
physical
15964851
RFXANK
Affinity Capture-Western
physical
15964851
CIITA
Affinity Capture-Western
physical
15964851
SMAD7
Affinity Capture-Western
physical
15831516
PRKD1
Affinity Capture-Western
physical
15728188
PPP2CA
Affinity Capture-Western
physical
18339811
DYRK1B
Biochemical Activity
physical
15546868
NFKBIA
Affinity Capture-Western
physical
15536134
NFKBIE
Reconstituted Complex
physical
15536134
HDAC5
Affinity Capture-Western
physical
18332106
HDAC4
Affinity Capture-Western
physical
18332106
HDAC4
Affinity Capture-Western
physical
18332106
CAMK2A
Affinity Capture-Western
physical
18292392
TBX3
Affinity Capture-Western
physical
18245468
SLC2A4RG
Reconstituted Complex
physical
18216015
MEF2C
Reconstituted Complex
physical
11279209
HDAC7
Reconstituted Complex
physical
11279209
NCOR1
Reconstituted Complex
physical
10860984
PRKAB1
Biochemical Activity
physical
18184930
PRKAB1
Affinity Capture-Western
physical
18184930
PHB2
Reconstituted Complex
physical
15140878
PHB2
Affinity Capture-Western
physical
15140878
MYEF2
Affinity Capture-Western
physical
15111488
AHRR
Affinity Capture-Western
physical
17949687
H3F3A
Affinity Capture-MS
physical
17403666
NR2E1
Affinity Capture-Western
physical
17873065
NR2E1
Affinity Capture-Western
physical
17873065
BCORL1
Affinity Capture-Western
physical
17379597
NFATC1
Biochemical Activity
physical
21413932
NFATC1
Affinity Capture-Western
physical
21413932
YWHAQ
Affinity Capture-Western
physical
20716686
PRKCD
Biochemical Activity
physical
21146494
BCL6
Affinity Capture-MS
physical
16147992
HDAC5
Affinity Capture-MS
physical
21081666
RBM25
Affinity Capture-MS
physical
21081666
NCOR1
Affinity Capture-MS
physical
21081666
NCOR2
Affinity Capture-MS
physical
21081666
TBL1X
Affinity Capture-MS
physical
21081666
TBL1XR1
Affinity Capture-MS
physical
21081666
GPS2
Affinity Capture-MS
physical
21081666
HDAC1
Affinity Capture-MS
physical
21081666
RBBP7
Affinity Capture-MS
physical
21081666
RBBP4
Affinity Capture-MS
physical
21081666
MTA2
Affinity Capture-MS
physical
21081666
PRKD1
Affinity Capture-MS
physical
21081666
PRKD2
Affinity Capture-MS
physical
21081666
PPP2R1A
Affinity Capture-MS
physical
21081666
PPP2R2A
Affinity Capture-MS
physical
21081666
PPP2CA
Affinity Capture-MS
physical
21081666
YWHAB
Affinity Capture-MS
physical
21081666
YWHAE
Affinity Capture-MS
physical
21081666
YWHAH
Affinity Capture-MS
physical
21081666
YWHAG
Affinity Capture-MS
physical
21081666
YWHAQ
Affinity Capture-MS
physical
21081666
YWHAZ
Affinity Capture-MS
physical
21081666
PRKDC
Affinity Capture-MS
physical
21081666
TP53
Affinity Capture-MS
physical
21081666
TUBB
Affinity Capture-MS
physical
21081666
TUBA1A
Affinity Capture-MS
physical
21081666
HSP90AB1
Affinity Capture-MS
physical
21081666
RBM39
Affinity Capture-MS
physical
21081666
HSPA1A
Affinity Capture-MS
physical
21081666
HNRNPA2B1
Affinity Capture-MS
physical
21081666
NUMA1
Affinity Capture-MS
physical
21081666
HIST4H4
Affinity Capture-MS
physical
21081666
HIST2H2AC
Affinity Capture-MS
physical
21081666
HIST1H2BK
Affinity Capture-MS
physical
21081666
HIST3H3
Affinity Capture-MS
physical
21081666
HDAC3
Affinity Capture-Western
physical
21081666
PRKD3
Affinity Capture-MS
physical
21081666
RAD50
Affinity Capture-MS
physical
21081666
MAP1B
Affinity Capture-MS
physical
21081666
USP9X
Affinity Capture-MS
physical
21081666
USP7
Affinity Capture-MS
physical
21081666
IARS
Affinity Capture-MS
physical
21081666
PSMA5
Affinity Capture-MS
physical
21081666
PRPF39
Affinity Capture-MS
physical
21081666
HCFC1
Affinity Capture-MS
physical
21081666
RUVBL1
Affinity Capture-MS
physical
21081666
BAG2
Affinity Capture-MS
physical
21081666
KIAA1967
Affinity Capture-MS
physical
21081666
UPF1
Affinity Capture-MS
physical
21081666
PSMC5
Affinity Capture-MS
physical
21081666
NUDC
Affinity Capture-MS
physical
21081666
GCN1L1
Affinity Capture-MS
physical
21081666
PSMD11
Affinity Capture-MS
physical
21081666
NEU1
Affinity Capture-MS
physical
21081666
CDK1
Affinity Capture-MS
physical
21081666
SF3A1
Affinity Capture-MS
physical
21081666
PSMC6
Affinity Capture-MS
physical
21081666
LTA4H
Affinity Capture-MS
physical
21081666
ETFA
Affinity Capture-MS
physical
21081666
COPB2
Affinity Capture-MS
physical
21081666
PCMT1
Affinity Capture-MS
physical
21081666
TNPO1
Affinity Capture-MS
physical
21081666
CSNK2A1
Affinity Capture-MS
physical
21081666
OGT
Affinity Capture-MS
physical
21081666
PGAM5
Affinity Capture-MS
physical
21081666
SF3B1
Affinity Capture-MS
physical
21081666
PSMD1
Affinity Capture-MS
physical
21081666
WDR5
Affinity Capture-MS
physical
21081666
GOT2
Affinity Capture-MS
physical
21081666
XPOT
Affinity Capture-MS
physical
21081666
RPL9
Affinity Capture-MS
physical
21081666
PRMT1
Affinity Capture-MS
physical
21081666
EIF3L
Affinity Capture-MS
physical
21081666
CAND1
Affinity Capture-MS
physical
21081666
DDX20
Affinity Capture-MS
physical
21081666
AHCY
Affinity Capture-MS
physical
21081666
HSD17B10
Affinity Capture-MS
physical
21081666
PPP2CB
Affinity Capture-MS
physical
21081666
LGALS3BP
Affinity Capture-MS
physical
21081666
SMC1A
Affinity Capture-MS
physical
21081666
STRAP
Affinity Capture-MS
physical
21081666
RPN2
Affinity Capture-MS
physical
21081666
DDOST
Affinity Capture-MS
physical
21081666
PSMD2
Affinity Capture-MS
physical
21081666
PSMC4
Affinity Capture-MS
physical
21081666
SF3B2
Affinity Capture-MS
physical
21081666
ECH1
Affinity Capture-MS
physical
21081666
TPI1
Affinity Capture-MS
physical
21081666
PSMD6
Affinity Capture-MS
physical
21081666
TUFM
Affinity Capture-MS
physical
21081666
PSMD3
Affinity Capture-MS
physical
21081666
PCNA
Affinity Capture-MS
physical
21081666
CS
Affinity Capture-MS
physical
21081666
SLC25A11
Affinity Capture-MS
physical
21081666
RAN
Affinity Capture-MS
physical
21081666
HSP90B1
Affinity Capture-MS
physical
21081666
RPL7
Affinity Capture-MS
physical
21081666
UQCRC2
Affinity Capture-MS
physical
21081666
SF3B3
Affinity Capture-MS
physical
21081666
RPL13
Affinity Capture-MS
physical
21081666
PRMT5
Affinity Capture-MS
physical
21081666
PHB
Affinity Capture-MS
physical
21081666
SMC3
Affinity Capture-MS
physical
21081666
RPL10A
Affinity Capture-MS
physical
21081666
LDHA
Affinity Capture-MS
physical
21081666
MDH2
Affinity Capture-MS
physical
21081666
PSMB5
Affinity Capture-MS
physical
21081666
HSPD1
Affinity Capture-MS
physical
21081666
HNRNPF
Affinity Capture-MS
physical
21081666
DDB1
Affinity Capture-MS
physical
21081666
SFXN1
Affinity Capture-MS
physical
21081666
ATP5A1
Affinity Capture-MS
physical
21081666
FLNA
Affinity Capture-MS
physical
21081666
OAT
Affinity Capture-MS
physical
21081666
VDAC1
Affinity Capture-MS
physical
21081666
HSPA4
Affinity Capture-MS
physical
21081666
TRAP1
Affinity Capture-MS
physical
21081666
ATP5B
Affinity Capture-MS
physical
21081666
PPP2R2D
Affinity Capture-MS
physical
21081666
RPN1
Affinity Capture-MS
physical
21081666
MTHFD1
Affinity Capture-MS
physical
21081666
PDIA6
Affinity Capture-MS
physical
21081666
PHGDH
Affinity Capture-MS
physical
21081666
CCT2
Affinity Capture-MS
physical
21081666
NME1
Affinity Capture-MS
physical
21081666
LARS
Affinity Capture-MS
physical
21081666
PCBP2
Affinity Capture-MS
physical
21081666
ALDOA
Affinity Capture-MS
physical
21081666
TRIM28
Affinity Capture-MS
physical
21081666
GANAB
Affinity Capture-MS
physical
21081666
ACTN4
Affinity Capture-MS
physical
21081666
HSP90AA1
Affinity Capture-MS
physical
21081666
DARS
Affinity Capture-MS
physical
21081666
ATP1A1
Affinity Capture-MS
physical
21081666
CANX
Affinity Capture-MS
physical
21081666
PGK1
Affinity Capture-MS
physical
21081666
P4HB
Affinity Capture-MS
physical
21081666
RPS8
Affinity Capture-MS
physical
21081666
RPLP0
Affinity Capture-MS
physical
21081666
CCT6A
Affinity Capture-MS
physical
21081666
PRPF19
Affinity Capture-MS
physical
21081666
HNRNPH2
Affinity Capture-MS
physical
21081666
PA2G4
Affinity Capture-MS
physical
21081666
FXR1
Affinity Capture-MS
physical
21081666
LRPPRC
Affinity Capture-MS
physical
21081666
HDAC3
Affinity Capture-MS
physical
21081666
VDAC2
Affinity Capture-MS
physical
21081666
EEF1G
Affinity Capture-MS
physical
21081666
CSE1L
Affinity Capture-MS
physical
21081666
PKM2
Affinity Capture-MS
physical
21081666
RPL3
Affinity Capture-MS
physical
21081666
PRDX3
Affinity Capture-MS
physical
21081666
ACAT1
Affinity Capture-MS
physical
21081666
COPB1
Affinity Capture-MS
physical
21081666
DNAJB11
Affinity Capture-MS
physical
21081666
EIF4A3
Affinity Capture-MS
physical
21081666
PPIA
Affinity Capture-MS
physical
21081666
C1QBP
Affinity Capture-MS
physical
21081666
MCM3
Affinity Capture-MS
physical
21081666
TCP1
Affinity Capture-MS
physical
21081666
MCM4
Affinity Capture-MS
physical
21081666
IMPDH2
Affinity Capture-MS
physical
21081666
RPSA
Affinity Capture-MS
physical
21081666
EIF4A1
Affinity Capture-MS
physical
21081666
CCT7
Affinity Capture-MS
physical
21081666
BAT1
Affinity Capture-MS
physical
21081666
ATP2A2
Affinity Capture-MS
physical
21081666
MCM2
Affinity Capture-MS
physical
21081666
IRS4
Affinity Capture-MS
physical
21081666
SLC25A1
Affinity Capture-MS
physical
21081666
EPRS
Affinity Capture-MS
physical
21081666
SLC25A3
Affinity Capture-MS
physical
21081666
PHB2
Affinity Capture-MS
physical
21081666
PRDX4
Affinity Capture-MS
physical
21081666
EIF3F
Affinity Capture-MS
physical
21081666
EIF3C
Affinity Capture-MS
physical
21081666
XRCC5
Affinity Capture-MS
physical
21081666
RUVBL2
Affinity Capture-MS
physical
21081666
NFS1
Affinity Capture-MS
physical
21081666
HNRPLL
Affinity Capture-MS
physical
21081666
PRPF8
Affinity Capture-MS
physical
21081666
CLTC
Affinity Capture-MS
physical
21081666
CCT4
Affinity Capture-MS
physical
21081666
EFTUD2
Affinity Capture-MS
physical
21081666
CCT5
Affinity Capture-MS
physical
21081666
GLUD1
Affinity Capture-MS
physical
21081666
XRCC6
Affinity Capture-MS
physical
21081666
MARS
Affinity Capture-MS
physical
21081666
XPO1
Affinity Capture-MS
physical
21081666
UBA1
Affinity Capture-MS
physical
21081666
TARS
Affinity Capture-MS
physical
21081666
RPS3A
Affinity Capture-MS
physical
21081666
FASN
Affinity Capture-MS
physical
21081666
KPNB1
Affinity Capture-MS
physical
21081666
MCM6
Affinity Capture-MS
physical
21081666
ACLY
Affinity Capture-MS
physical
21081666
SRSF1
Affinity Capture-MS
physical
21081666
HNRNPD
Affinity Capture-MS
physical
21081666
SLC25A6
Affinity Capture-MS
physical
21081666
CCT8
Affinity Capture-MS
physical
21081666
CAD
Affinity Capture-MS
physical
21081666
NPEPPS
Affinity Capture-MS
physical
21081666
CCT3
Affinity Capture-MS
physical
21081666
TUBB2C
Affinity Capture-MS
physical
21081666
EIF3B
Affinity Capture-MS
physical
21081666
PRDX6
Affinity Capture-MS
physical
21081666
ILF2
Affinity Capture-MS
physical
21081666
CDC5L
Affinity Capture-MS
physical
21081666
SHMT2
Affinity Capture-MS
physical
21081666
DNAJA1
Affinity Capture-MS
physical
21081666
PTBP1
Affinity Capture-MS
physical
21081666
HSPA9
Affinity Capture-MS
physical
21081666
RPS11
Affinity Capture-MS
physical
21081666
APLP2
Affinity Capture-MS
physical
21081666
DHX15
Affinity Capture-MS
physical
21081666
RPL5
Affinity Capture-MS
physical
21081666
RPS3
Affinity Capture-MS
physical
21081666
RARS
Affinity Capture-MS
physical
21081666
CKB
Affinity Capture-MS
physical
21081666
ALDH18A1
Affinity Capture-MS
physical
21081666
PPP1CA
Affinity Capture-MS
physical
21081666
NONO
Affinity Capture-MS
physical
21081666
SNRNP200
Affinity Capture-MS
physical
21081666
DDX1
Affinity Capture-MS
physical
21081666
VCP
Affinity Capture-MS
physical
21081666
HSPA5
Affinity Capture-MS
physical
21081666
DDX17
Affinity Capture-MS
physical
21081666
RPL7A
Affinity Capture-MS
physical
21081666
TKT
Affinity Capture-MS
physical
21081666
PABPC1
Affinity Capture-MS
physical
21081666
MCM5
Affinity Capture-MS
physical
21081666
TFRC
Affinity Capture-MS
physical
21081666
EMD
Affinity Capture-MS
physical
21081666
QARS
Affinity Capture-MS
physical
21081666
MCM7
Affinity Capture-MS
physical
21081666
RPS4X
Affinity Capture-MS
physical
21081666
RPL4
Affinity Capture-MS
physical
21081666
CKMT1B
Affinity Capture-MS
physical
21081666
NUP93
Affinity Capture-MS
physical
21081666
HNRNPL
Affinity Capture-MS
physical
21081666
SFPQ
Affinity Capture-MS
physical
21081666
RBM14
Affinity Capture-MS
physical
21081666
PARP1
Affinity Capture-MS
physical
21081666
ADAR
Affinity Capture-MS
physical
21081666
ILF3
Affinity Capture-MS
physical
21081666
NPM1
Affinity Capture-MS
physical
21081666
DHX9
Affinity Capture-MS
physical
21081666
HIST1H1C
Affinity Capture-MS
physical
21081666
IGF2BP1
Affinity Capture-MS
physical
21081666
DDX3X
Affinity Capture-MS
physical
21081666
MYH9
Affinity Capture-MS
physical
21081666
HNRNPA1
Affinity Capture-MS
physical
21081666
HADHA
Affinity Capture-MS
physical
21081666
HNRNPA3
Affinity Capture-MS
physical
21081666
DDX47
Affinity Capture-MS
physical
21081666
HNRNPR
Affinity Capture-MS
physical
21081666
NOP2
Affinity Capture-MS
physical
21081666
RBMX
Affinity Capture-MS
physical
21081666
TOP1
Affinity Capture-MS
physical
21081666
NFKB1
Reconstituted Complex
physical
12917325
SF1
Reconstituted Complex
physical
12917325
NFKB1
Affinity Capture-Western
physical
12917325
SF1
Affinity Capture-Western
physical
12917325