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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TNK2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0007264 small GTPase mediated signal transduction TAS GO:0016310 phosphorylation IDA GO:0016567 protein ubiquitination ISS GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IDA cellular_component GO:0005634 nucleus IDA GO:0005737 cytoplasm IDA GO:0005768 endosome ISS GO:0005886 plasma membrane IDA GO:0005912 adherens junction IEA GO:0030054 cell junction IEA GO:0030424 axon IEA GO:0030425 dendrite IEA GO:0030426 growth cone IEA GO:0030659 cytoplasmic vesicle membrane IEA GO:0031410 cytoplasmic vesicle IEA GO:0043025 neuronal cell body IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004713 protein tyrosine kinase activity IDA GO:0004713 protein tyrosine kinase activity IEA GO:0004715 non-membrane spanning protein tyrosine kinase activity IEA GO:0005095 GTPase inhibitor activity TAS GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0046872 metal ion binding IEA

Protein-protein interaction details for TNK2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID HSH2D Two-hybrid physical 11700021 GRB2 Affinity Capture-Western physical 8647288 GRB2 Affinity Capture-Western physical 11394904 CDC42 Affinity Capture-Western physical 11394904 CLTC Reconstituted Complex physical 11278436 HSH2D Biochemical Activity physical 11700021 HSH2D Affinity Capture-Western physical 11700021 HSH2D Affinity Capture-Western physical 11700021 FYN Affinity Capture-Western physical 11087735 FYN Reconstituted Complex physical 11087735 MCF2 Affinity Capture-Western physical 10652228 GRB2 Two-hybrid physical 20936779 CDC42 Two-hybrid physical 20936779 EGFR Affinity Capture-Western physical 20086093 UBC Affinity Capture-Western physical 20086093 NEDD4 Affinity Capture-Western physical 20086093 GRB2 Affinity Capture-Western physical 20086093 NEDD4 Biochemical Activity physical 20086093 NEDD4 Reconstituted Complex physical 20086093 NEDD4 Reconstituted Complex physical 20086093 CDC42 Affinity Capture-Western physical 20086093 CLTA Reconstituted Complex physical 19144635 AMPH Reconstituted Complex physical 19144635 BIN1 Reconstituted Complex physical 19144635 FABP4 Reconstituted Complex physical 19144635 NEDD4L Reconstituted Complex physical 19144635 CLTA Affinity Capture-Western physical 19144635 AMPH Affinity Capture-Western physical 19144635 BIN1 Affinity Capture-Western physical 19144635 FABP4 Affinity Capture-Western physical 19144635 NEDD4L Affinity Capture-Western physical 19144635 NEDD4L Affinity Capture-Western physical 19144635 NEDD4L Reconstituted Complex physical 19144635 SMURF1 Reconstituted Complex physical 19144635 WWP2 Reconstituted Complex physical 19144635 HECW1 Reconstituted Complex physical 19144635 BAG3 Reconstituted Complex physical 19144635 MAGI3 Reconstituted Complex physical 19144635 WWOX Reconstituted Complex physical 19144635 SRC Reconstituted Complex physical 19144635 NEDD4L Co-localization physical 19144635 UBC Affinity Capture-Western physical 19144635