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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for STUB1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000209 protein polyubiquitination IDA GO:0000209 protein polyubiquitination IMP GO:0006281 DNA repair IEA GO:0006511 ubiquitin-dependent protein catabolic process IMP GO:0006515 misfolded or incompletely synthesized protein catabolic process IDA GO:0016567 protein ubiquitination TAS GO:0030579 ubiquitin-dependent SMAD protein catabolic process IDA GO:0031398 positive regulation of protein ubiquitination IDA GO:0031943 regulation of glucocorticoid metabolic process IDA GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IDA GO:0043161 proteasomal ubiquitin-dependent protein catabolic process IDA GO:0051604 protein maturation TAS GO:0051865 protein autoubiquitination IDA GO:0070534 protein K63-linked ubiquitination IDA GO:0071218 cellular response to misfolded protein IDA GO:0090035 positive regulation of cellular chaperone-mediated protein complex assembly IDA cellular_component GO:0000151 ubiquitin ligase complex IDA GO:0005737 cytoplasm IDA GO:0031371 ubiquitin conjugating enzyme complex TAS GO:0042405 nuclear inclusion body IDA molecular_function GO:0004842 ubiquitin-protein ligase activity IDA GO:0004842 ubiquitin-protein ligase activity IMP GO:0004842 ubiquitin-protein ligase activity TAS GO:0005515 protein binding IPI GO:0016874 ligase activity IEA GO:0019899 enzyme binding IPI GO:0019900 kinase binding IPI GO:0030544 Hsp70 protein binding IDA GO:0030674 protein binding, bridging TAS GO:0030911 TPR domain binding IDA GO:0034450 ubiquitin-ubiquitin ligase activity ISS GO:0042803 protein homodimerization activity ISS GO:0046332 SMAD binding IDA GO:0051787 misfolded protein binding IDA GO:0051879 Hsp90 protein binding IDA

Protein-protein interaction details for STUB1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID MPP1 Two-hybrid physical 16169070 KHDRBS1 Two-hybrid physical 16169070 UBE2D2 Reconstituted Complex physical 11676916 BAG1 Reconstituted Complex physical 11676916 HSPA8 Reconstituted Complex physical 10330192 HSPA4 Reconstituted Complex physical 10330192 DNAJB1 Reconstituted Complex physical 10330192 HSPA1A Reconstituted Complex physical 10330192 HSPA8 Affinity Capture-Western physical 10330192 HSPA4 Affinity Capture-Western physical 10330192 DNAJB1 Affinity Capture-Western physical 10330192 HSPA1A Affinity Capture-Western physical 10330192 HSPA8 Two-hybrid physical 10330192 HSPA4 Two-hybrid physical 10330192 DNAJB1 Two-hybrid physical 10330192 PARK2 Affinity Capture-MS physical 12150907 PARK2 Affinity Capture-Western physical 12150907 GPR37 Affinity Capture-Western physical 12150907 PARK2 Reconstituted Complex physical 12150907 HSPA1A Reconstituted Complex physical 12150907 CYP3A4 Biochemical Activity physical 19103148 RAF1 Affinity Capture-Western physical 19011619 RAF1 Reconstituted Complex physical 19011619 XIAP Reconstituted Complex physical 19011619 RUNX2 Affinity Capture-Western physical 18541707 RUNX2 Two-hybrid physical 18541707 AKT1 Affinity Capture-Western physical 18292230 MAPT Affinity Capture-Western physical 18292230 TP53 Affinity Capture-Western physical 18223694 STUB1 Biochemical Activity physical 18485199 UBE2D1 Reconstituted Complex physical 18485199 UBE2E2 Reconstituted Complex physical 18485199 GUCY1A2 Affinity Capture-Western physical 17873020 GUCY1A2 Biochemical Activity physical 17873020 UBE2D1 Reconstituted Complex physical 17873020 UBA1 Reconstituted Complex physical 17873020 TAL1 Affinity Capture-Western physical 17962192 MAP3K5 Affinity Capture-Western physical 17595347 HSP90AA1 Affinity Capture-Western physical 17324930 AHR Affinity Capture-Western physical 17209571 MCF2 Reconstituted Complex physical 17178836 EGFR PCA physical 20029029 ATXN1 Affinity Capture-Western physical 16831871 ATXN1 Biochemical Activity physical 16831871 MST1R Biochemical Activity physical 16740632 MST1R Affinity Capture-Western physical 16740632 VCP Affinity Capture-Western physical 16621797 EIF4E Affinity Capture-Western physical 16720573 STUB1 Biochemical Activity physical 16714300 UBE2N Reconstituted Complex physical 16307917 UBE2V1 Reconstituted Complex physical 16307917 HSP90AA1 Reconstituted Complex physical 16307917 BAG2 Reconstituted Complex physical 16169850 HSPA4 Reconstituted Complex physical 16169850 BAG2 Reconstituted Complex physical 16169850 AIMP2 Affinity Capture-Western physical 16135753 MAP3K5 Affinity Capture-Western physical 16038411 ESR1 Affinity Capture-Western physical 16037132 CFTR Biochemical Activity physical 15611333 HSPA8 Affinity Capture-Western physical 15538384 ESR1 Affinity Capture-Western physical 15538384 ESR1 Affinity Capture-Western physical 15538384 ESR1 Reconstituted Complex physical 15538384 DNAJC13 Affinity Capture-MS physical 15538384 HSP90AA1 Affinity Capture-MS physical 15538384 HSPA4 Affinity Capture-MS physical 15538384 HSPA8 Affinity Capture-MS physical 15538384 BAG1 Affinity Capture-Western physical 15538384 HSP90AA1 Affinity Capture-Western physical 15538384 HSPA4 Affinity Capture-Western physical 15538384 STUB1 Affinity Capture-Western physical 15538384 PARK7 Affinity Capture-Western physical 15525661 NOS1 Biochemical Activity physical 15466472 NOS1 Affinity Capture-Western physical 15466472 MAPT Biochemical Activity physical 15447663 MAPT Affinity Capture-Western physical 15447663 MAPT Affinity Capture-Western physical 15447663 SOD1 Affinity Capture-Western physical 15358145 UBC Affinity Capture-Western physical 15358145 MEN1 Affinity Capture-Western physical 15254225 FBXO2 Affinity Capture-Western physical 16682404 FBXO2 Reconstituted Complex physical 16682404 FBXO27 Reconstituted Complex physical 16682404 FBXO2 Biochemical Activity physical 16682404 MAPT Affinity Capture-Western physical 14962978 ERBB2 Affinity Capture-Western physical 12239347 UBE2D3 Reconstituted Complex physical 11743028 STUB1 Biochemical Activity physical 11743028 UBC Reconstituted Complex physical 11743028 UBE2D1 Reconstituted Complex physical 11557750 HSPA8 Biochemical Activity physical 11557750 NR3C1 Affinity Capture-Western physical 11146632 HSP90AA1 Affinity Capture-Western physical 11146632 UBC Affinity Capture-Western physical 11146632 UBC Affinity Capture-Western physical 11146632 PSMD4 Reconstituted Complex physical 11146632 RUNX1 Affinity Capture-Western physical 19524548 RUNX1 Reconstituted Complex physical 19524548 RUNX1 Affinity Capture-Western physical 19524548 LRRK2 Affinity Capture-Western physical 19196961 LRRK2 Affinity Capture-Western physical 19196961 HSP90AA1 Affinity Capture-Western physical 19196961 HSPA4 Affinity Capture-Western physical 19196961 FOXO1 Affinity Capture-Western physical 19483080 GUCY1B3 Affinity Capture-Western physical 19478201 GUCY1A3 Affinity Capture-Western physical 19478201 DAXX Affinity Capture-Western physical 19465479 DAXX Reconstituted Complex physical 19465479 HSPA4 Biochemical Activity physical 19648119 TERF1 Affinity Capture-MS physical 20811636 TERF2 Affinity Capture-MS physical 20811636 ERBB2 Affinity Capture-Western physical 17239458 ERBB2 Reconstituted Complex physical 17239458 SOD1 Affinity Capture-Western physical 17157513 APP Affinity Capture-Western physical 17317785 APP Affinity Capture-Western physical 17317785 HSPD1 Affinity Capture-Western physical 17317785 HSPA4 Affinity Capture-Western physical 17317785 HSP90AA1 Affinity Capture-Western physical 17317785 HSPD1 Affinity Capture-Western physical 17317785 HSPA4 Affinity Capture-Western physical 17317785 HSP90AA1 Affinity Capture-Western physical 17317785 SMAD1 Affinity Capture-Western physical 21454478 SMAD1 Co-crystal Structure physical 21454478 HSPA4 Co-crystal Structure physical 21454478 HSPA8 Co-crystal Structure physical 21454478 HSPA4 Reconstituted Complex physical 21454478 HSPA8 Reconstituted Complex physical 21454478 SMAD5 Affinity Capture-Western physical 21454478 HSPA4 Reconstituted Complex physical 21454478 HSP90AA1 Reconstituted Complex physical 21454478 HSPA8 Reconstituted Complex physical 21454478 AKT1 Affinity Capture-Western physical 21767636 NQO1 Biochemical Activity physical 21220432 NQO1 Affinity Capture-Western physical 21220432 IRF1 Reconstituted Complex physical 20947504 IRF1 Affinity Capture-Western physical 20947504 IRF1 Reconstituted Complex physical 20947504 IRF1 Biochemical Activity physical 20947504 ATXN3 Affinity Capture-Western physical 21855799 PSMD4 Reconstituted Complex physical 21855799 ATXN3 Reconstituted Complex physical 21855799 ATXN3 Biochemical Activity physical 21855799 SMAD1 Biochemical Activity physical 21454478 HSPA8 Reconstituted Complex physical 20618441 HSP90AA1 Reconstituted Complex physical 20618441 TP53 Biochemical Activity physical 20618441 STUB1 Reconstituted Complex physical 20146531 HSPA4 Reconstituted Complex physical 20146531 HSP90AA1 Reconstituted Complex physical 20146531 UBE2D1 Reconstituted Complex physical 20146531 UBE2N Reconstituted Complex physical 20146531 SENP3 Affinity Capture-Western physical 20924358 SENP3 Affinity Capture-Western physical 20924358 HSPA4 Biochemical Activity physical 19913553 HSP90AA1 Biochemical Activity physical 19913553 TLR4 Affinity Capture-Western physical 21911421 TLR9 Affinity Capture-Western physical 21911421 HSPA8 Reconstituted Complex physical 21911421 TRAF6 Reconstituted Complex physical 21911421 PRKCZ Reconstituted Complex physical 21911421 SRC Reconstituted Complex physical 21911421 HSPA8 Affinity Capture-Western physical 21911421 TRAF6 Affinity Capture-Western physical 21911421 PRKCZ Affinity Capture-Western physical 21911421 SRC Affinity Capture-Western physical 21911421 PRKCZ Co-localization physical 21911421 SRC Co-localization physical 21911421 PRKCZ Biochemical Activity physical 21911421 SRC Biochemical Activity physical 21911421 HSPA4 Affinity Capture-Western physical 21549100 AR Affinity Capture-Western physical 19706771 MYOCD Affinity Capture-Western physical 19237536 MYOCD Affinity Capture-Western physical 19237536 MYOCD Reconstituted Complex physical 19237536 HSPA4 Co-fractionation physical 20704274 HSP90AA1 Co-fractionation physical 20704274 HSPA4 Biochemical Activity physical 20704274 HSP90AA1 Biochemical Activity physical 20704274 HSP90AA1 Reconstituted Complex physical 20704274 MYOCD Co-localization physical 19237536 MYOCD Biochemical Activity physical 19237536 UBC Reconstituted Complex physical 18042044 UBC Biochemical Activity physical 18042044 POLB Biochemical Activity physical 19713937 HSP90AA1 Affinity Capture-Western physical 18784277 HSPA4 Affinity Capture-Western physical 18784277 PSMD4 Biochemical Activity physical 19240029 PPP2R1A Affinity Capture-Western physical 19818709 CYP3A4 Biochemical Activity physical 22101235 HIF1A Affinity Capture-MS physical 19940151 HIF1A Affinity Capture-Western physical 19940151 HSPA4 Affinity Capture-Western physical 19940151 HIF1A Affinity Capture-Western physical 19940151 HIF1A Reconstituted Complex physical 19940151 EPAS1 Affinity Capture-Western physical 19940151 ARRB1 Affinity Capture-Western physical 19306926 ARRB2 Affinity Capture-Western physical 19306926 LRRK2 Affinity Capture-Western physical 19536328 LRRK2 Affinity Capture-Western physical 19536328 SMAD1 Two-hybrid physical 14701756 SMAD1 Reconstituted Complex physical 14701756 SMAD4 Reconstituted Complex physical 14701756 SMAD2 Reconstituted Complex physical 14701756 SMAD3 Reconstituted Complex physical 14701756 SMAD1 Affinity Capture-Western physical 14701756 SMAD4 Affinity Capture-Western physical 14701756 SMAD1 Affinity Capture-Western physical 14701756 ABL1 Biochemical Activity physical 20675402 MAPT Biochemical Activity physical 20466727 MAPT Affinity Capture-Western physical 20466727 BCR Biochemical Activity physical 20675402 BAG1 Biochemical Activity physical 20675402 ATXN3 Biochemical Activity physical 20943656 ATXN3 Biochemical Activity physical 20943656 NOS1 Biochemical Activity physical 20729196 CYP2E1 Biochemical Activity physical 21209460 UBC Affinity Capture-MS physical 22118674 UBE2D1 Reconstituted Complex physical 21518764 UBE2D2 Reconstituted Complex physical 21518764 UBE2D3 Reconstituted Complex physical 21518764 UBE2E1 Reconstituted Complex physical 21518764 UBE2E2 Reconstituted Complex physical 21518764 UBE2E3 Reconstituted Complex physical 21518764 UBE2N Reconstituted Complex physical 21518764 UBE2W Reconstituted Complex physical 21518764 STUB1 Biochemical Activity physical 21518764 HSPA4 Biochemical Activity physical 21518764 MAPT Co-purification physical 14612456 UBE2D2 Co-purification physical 14612456 MAPT Biochemical Activity physical 14612456 MAPT Affinity Capture-Western physical 14612456 SGK1 Affinity Capture-Western physical 20947508 SGK1 Affinity Capture-Western physical 20947508 STUB1 Biochemical Activity physical 12574167 ERBB2 Biochemical Activity physical 12574167 HSPA4 Affinity Capture-Western physical 12574167 HSP90AA1 Affinity Capture-Western physical 12574167 ERBB2 Affinity Capture-Western physical 12574167 CD4 Affinity Capture-Western physical 20974815 DRD4 Affinity Capture-Western physical 20974815 AVPR2 Affinity Capture-Western physical 20974815 MAP3K2 Affinity Capture-Western physical 20588253 MAP3K2 Reconstituted Complex physical 20588253 MAP3K2 Biochemical Activity physical 20588253 STUB1 Biochemical Activity physical 21358815 HSPA4 Biochemical Activity physical 21358815 SNCA Biochemical Activity physical 21358815 BAG5 Reconstituted Complex physical 21358815 BAG5 Affinity Capture-Western physical 21358815 SNCA Affinity Capture-Western physical 21358815 MAP3K5 Affinity Capture-Western physical 20349136 MAP3K5 Affinity Capture-Western physical 20349136 HSPA4 Affinity Capture-Western physical 20349136 HSPA4 Affinity Capture-Western physical 20349136 AR Reconstituted Complex physical 21157430 AR Biochemical Activity physical 21157430 VHL Affinity Capture-MS physical 21942715 CFTR Biochemical Activity physical 19056735 CFTR Biochemical Activity physical 21898230