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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NOD1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000187 activation of MAPK activity TAS GO:0002218 activation of innate immune response TAS GO:0002224 toll-like receptor signaling pathway TAS GO:0002606 positive regulation of dendritic cell antigen processing and presentation IEA GO:0002606 positive regulation of dendritic cell antigen processing and presentation ISS GO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS GO:0006915 apoptosis TAS GO:0006917 induction of apoptosis IDA GO:0006919 activation of caspase activity IDA GO:0006919 activation of caspase activity TAS GO:0006952 defense response TAS GO:0006954 inflammatory response TAS GO:0007165 signal transduction TAS GO:0007254 JNK cascade TAS GO:0008063 Toll signaling pathway TAS GO:0009595 detection of biotic stimulus TAS GO:0016045 detection of bacterium IDA GO:0032755 positive regulation of interleukin-6 production IEA GO:0032760 positive regulation of tumor necrosis factor production IEA GO:0032874 positive regulation of stress-activated MAPK cascade IEA GO:0034130 toll-like receptor 1 signaling pathway TAS GO:0034134 toll-like receptor 2 signaling pathway TAS GO:0034138 toll-like receptor 3 signaling pathway TAS GO:0034142 toll-like receptor 4 signaling pathway TAS GO:0035556 intracellular signal transduction IDA GO:0042228 interleukin-8 biosynthetic process IDA GO:0042742 defense response to bacterium IDA GO:0042981 regulation of apoptosis IEA GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IDA GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IEA GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IEP GO:0045087 innate immune response TAS GO:0046330 positive regulation of JNK cascade IEA GO:0050830 defense response to Gram-positive bacterium IEA GO:0051092 positive regulation of NF-kappaB transcription factor activity IDA GO:0051092 positive regulation of NF-kappaB transcription factor activity TAS GO:0051259 protein oligomerization TAS GO:0051403 stress-activated MAPK cascade TAS GO:0070374 positive regulation of ERK1 and ERK2 cascade IEA GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway TAS cellular_component GO:0005622 intracellular IEA GO:0005737 cytoplasm IDA GO:0005737 cytoplasm TAS GO:0005829 cytosol TAS GO:0005886 plasma membrane IEA GO:0016323 basolateral plasma membrane IDA molecular_function GO:0000166 nucleotide binding IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0008656 caspase activator activity TAS GO:0042802 identical protein binding IDA GO:0042802 identical protein binding IPI GO:0042803 protein homodimerization activity IPI GO:0042834 peptidoglycan binding TAS GO:0050700 CARD domain binding IDA

Protein-protein interaction details for NOD1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID NLRC4 Affinity Capture-Western physical 15107016 CARD6 Affinity Capture-Western physical 12775719 NOD1 Affinity Capture-Western physical 10329646 CASP1 Affinity Capture-Western physical 10329646 CASP2 Affinity Capture-Western physical 10329646 CASP4 Affinity Capture-Western physical 10329646 CASP8 Affinity Capture-Western physical 10329646 CASP9 Affinity Capture-Western physical 10329646 RIPK2 Affinity Capture-Western physical 10329646 CFLAR Affinity Capture-Western physical 10329646