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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CTCF (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006349regulation of gene expression by genetic imprintingIEA
GO:0006351transcription, DNA-dependentIDA
GO:0006355regulation of transcription, DNA-dependentIEA
GO:0007059chromosome segregationIEA
GO:0010216maintenance of DNA methylationIEA
GO:0010628positive regulation of gene expressionIEA
GO:0010628positive regulation of gene expressionIMP
GO:0010629negative regulation of gene expressionIEA
GO:0016568chromatin modificationIEA
GO:0016584nucleosome positioningIDA
GO:0031060regulation of histone methylationIEA
GO:0035065regulation of histone acetylationIEA
GO:0040029regulation of gene expression, epigeneticIMP
GO:0040030regulation of molecular function, epigeneticIMP
GO:0045892negative regulation of transcription, DNA-dependentIDA
GO:0045893positive regulation of transcription, DNA-dependentIDA
GO:0045893positive regulation of transcription, DNA-dependentIMP
GO:0070602regulation of centromeric sister chromatid cohesionNAS
cellular_component
GO:0000775chromosome, centromeric regionIDA
GO:0000793condensed chromosomeIDA
GO:0005622intracellularIEA
GO:0005634nucleusIDA
GO:0005634nucleusIEA
GO:0005654nucleoplasmIDA
GO:0005730nucleolusIDA
molecular_function
GO:0003676nucleic acid bindingIEA
GO:0003677DNA bindingIEA
GO:0003700sequence-specific DNA binding transcription factor activityIDA
GO:0003714transcription corepressor activityTAS
GO:0008270zinc ion bindingIEA
GO:0008270zinc ion bindingTAS
GO:0043035chromatin insulator sequence bindingIDA
GO:0043565sequence-specific DNA bindingIDA
GO:0044212transcription regulatory region DNA bindingIDA
GO:0046872metal ion bindingIEA

Protein-protein interaction details for CTCF (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
YBX1Affinity Capture-MSphysical10906122
YBX1Affinity Capture-Westernphysical10906122
YBX1Affinity Capture-Westernphysical10906122
YBX1Reconstituted Complexphysical10906122
CHD8Reconstituted Complexphysical16949368
CHD8Affinity Capture-Westernphysical16949368
CHD8Two-hybridphysical16949368
CHD7Protein-peptidephysical17603073
SUZ12Affinity Capture-Westernphysical18662993
SUZ12Reconstituted Complexphysical18662993
SUZ12Two-hybridphysical18662993
YY1Affinity Capture-Westernphysical17218270
POLR2AAffinity Capture-Westernphysical17210645
POLR2ACo-purificationphysical17210645
POLR2AAffinity Capture-Westernphysical17210645
POLR2AReconstituted Complexphysical17210645
RAD21Affinity Capture-Westernphysical18219272
SMC1AAffinity Capture-Westernphysical18219272
SIN3AReconstituted Complexphysical10734189
SMAD3Affinity Capture-Westernphysical20427289
SMAD3Affinity Capture-Westernphysical20427289
SMAD3Reconstituted Complexphysical20427289
TRB@Reconstituted Complexphysical20404925
RXRAReconstituted Complexphysical20404925
TRB@Reconstituted Complexphysical20404925
RXRAReconstituted Complexphysical20404925
PARP1Affinity Capture-Westernphysical20038529
PARP1Affinity Capture-Westernphysical20038529
PARP1Co-localizationphysical20038529
NPM1Affinity Capture-MSphysical14759373
TOP2AAffinity Capture-MSphysical14759373
PARP1Affinity Capture-MSphysical14759373
LMNAAffinity Capture-MSphysical14759373
KPNA4Affinity Capture-MSphysical14759373
KPNA2Affinity Capture-MSphysical14759373
TAF1Affinity Capture-MSphysical14759373
HIST2H2ACAffinity Capture-MSphysical14759373
H2AFZAffinity Capture-MSphysical14759373
NPM1Affinity Capture-MSphysical14759373
NPM1Affinity Capture-Westernphysical14759373