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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MALT1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001923 B-1 B cell differentiation IEA GO:0002237 response to molecule of bacterial origin IEA GO:0002726 positive regulation of T cell cytokine production IMP GO:0006508 proteolysis IDA GO:0006916 anti-apoptosis NAS GO:0006952 defense response NAS GO:0007250 activation of NF-kappaB-inducing kinase activity IMP GO:0009620 response to fungus IEA GO:0016567 protein ubiquitination IDA GO:0031398 positive regulation of protein ubiquitination NAS GO:0032743 positive regulation of interleukin-2 production IMP GO:0042098 T cell proliferation IEA GO:0042113 B cell activation IEA GO:0042327 positive regulation of phosphorylation IMP GO:0042981 regulation of apoptosis IDA GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IMP GO:0045087 innate immune response IEA GO:0050852 T cell receptor signaling pathway IDA GO:0050852 T cell receptor signaling pathway TAS GO:0050856 regulation of T cell receptor signaling pathway IEA GO:0050870 positive regulation of T cell activation IC GO:0051092 positive regulation of NF-kappaB transcription factor activity IMP GO:0051168 nuclear export IDA GO:0051259 protein oligomerization IDA cellular_component GO:0005634 nucleus IDA GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA GO:0005829 cytosol TAS GO:0032449 CBM complex NAS GO:0043234 protein complex IDA GO:0048471 perinuclear region of cytoplasm IEA molecular_function GO:0002020 protease binding IEA GO:0004197 cysteine-type endopeptidase activity NAS GO:0004842 ubiquitin-protein ligase activity IDA GO:0004871 signal transducer activity IMP GO:0005515 protein binding IPI GO:0008233 peptidase activity IDA GO:0019209 kinase activator activity IMP GO:0043621 protein self-association IPI

Protein-protein interaction details for MALT1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID BCL10 Two-hybrid physical 11090634 UBE2G2 Affinity Capture-MS physical 17353931 BCL10 Reconstituted Complex physical 11090634 BCL10 Affinity Capture-Western physical 11090634 TRAF6 Affinity Capture-Western physical 15125833 TRAF6 Reconstituted Complex physical 15125833 TRAF2 Reconstituted Complex physical 15125833 BCL10 Affinity Capture-Western physical 19279678 NFKBIA Affinity Capture-Western physical 20551178 CSNK1A1 Affinity Capture-Western physical 20551178 BCL10 Affinity Capture-Western physical 20551178 UBC Affinity Capture-Western physical 20551178 UBC Affinity Capture-Western physical 19494296 UBC Affinity Capture-Western physical 19494296 IKBKG Affinity Capture-Western physical 19494296 COPS5 Affinity Capture-Western physical 19444310 BCL10 Affinity Capture-Western physical 19444310 GPS1 Affinity Capture-Western physical 19444310 CAMK2G Affinity Capture-Western physical 21513986 BCL10 Affinity Capture-Western physical 21513986