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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MAPK14 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000077 DNA damage checkpoint IEA GO:0000187 activation of MAPK activity TAS GO:0000902 cell morphogenesis IEA GO:0001525 angiogenesis IEA GO:0002062 chondrocyte differentiation IEA GO:0002224 toll-like receptor signaling pathway TAS GO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS GO:0006006 glucose metabolic process IEA GO:0006928 cellular component movement TAS GO:0006935 chemotaxis TAS GO:0006950 response to stress IDA GO:0006950 response to stress IEA GO:0007165 signal transduction TAS GO:0007166 cell surface receptor linked signaling pathway TAS GO:0007243 intracellular protein kinase cascade IDA GO:0007243 intracellular protein kinase cascade IEA GO:0007265 Ras protein signal transduction TAS GO:0007519 skeletal muscle tissue development IEA GO:0007596 blood coagulation TAS GO:0008063 Toll signaling pathway TAS GO:0009749 response to glucose stimulus IEA GO:0016070 RNA metabolic process TAS GO:0016071 mRNA metabolic process TAS GO:0018105 peptidyl-serine phosphorylation IEA GO:0019395 fatty acid oxidation IEA GO:0030168 platelet activation TAS GO:0031663 lipopolysaccharide-mediated signaling pathway IEA GO:0032495 response to muramyl dipeptide IEA GO:0032496 response to lipopolysaccharide IEA GO:0034130 toll-like receptor 1 signaling pathway TAS GO:0034134 toll-like receptor 2 signaling pathway TAS GO:0034138 toll-like receptor 3 signaling pathway TAS GO:0034142 toll-like receptor 4 signaling pathway TAS GO:0042692 muscle cell differentiation TAS GO:0042770 signal transduction in response to DNA damage IMP GO:0045087 innate immune response TAS GO:0045648 positive regulation of erythrocyte differentiation IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0046777 protein autophosphorylation IEA GO:0048010 vascular endothelial growth factor receptor signaling pathway IMP GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0051090 regulation of sequence-specific DNA binding transcription factor activity TAS GO:0051149 positive regulation of muscle cell differentiation TAS GO:0051403 stress-activated MAPK cascade IEA GO:0051403 stress-activated MAPK cascade TAS GO:0071363 cellular response to growth factor stimulus IMP GO:0071479 cellular response to ionizing radiation IMP GO:0090400 stress-induced premature senescence IMP GO:2000379 positive regulation of reactive oxygen species metabolic process IMP cellular_component GO:0000922 spindle pole IEA GO:0005623 cell IEA GO:0005625 soluble fraction IEA GO:0005634 nucleus IEA GO:0005634 nucleus ISS GO:0005654 nucleoplasm TAS GO:0005737 cytoplasm IEA GO:0005737 cytoplasm ISS GO:0005739 mitochondrion IEA GO:0005829 cytosol TAS GO:0044445 cytosolic part IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004674 protein serine/threonine kinase activity IEA GO:0004674 protein serine/threonine kinase activity TAS GO:0004707 MAP kinase activity IDA GO:0004707 MAP kinase activity IEA GO:0004708 MAP kinase kinase activity TAS GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0008022 protein C-terminus binding IEA

Protein-protein interaction details for MAPK14 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID HTRA2 Two-hybrid physical 10644717 DUSP10 Two-hybrid physical 10391943 ZFP36L1 Two-hybrid physical 16189514 ZFP36L1 Affinity Capture-Western physical 16189514 CDC25A Reconstituted Complex physical 12963847 SLC12A2 Affinity Capture-Western physical 14563843 STK39 Affinity Capture-Western physical 14563843 MAPK14 Two-hybrid physical 12819782 KARS Two-hybrid physical 12819782 FUBP1 Two-hybrid physical 12819782 FUBP1 Affinity Capture-Western physical 12819782 FUBP1 Reconstituted Complex physical 12819782 MAP2K6 Biochemical Activity physical 12697810 MAPK1 Affinity Capture-Western physical 12697810 MAPK3 Affinity Capture-Western physical 12697810 SMAD7 Affinity Capture-Western physical 12589052 RPS6KA4 Two-hybrid physical 9792677 RPS6KA4 Affinity Capture-Western physical 9792677 RPS6KA4 Reconstituted Complex physical 9792677 RPS6KA4 Biochemical Activity physical 9792677 RPS6KA4 Phenotypic Enhancement genetic 9792677 AKT1 Affinity Capture-Western physical 11042204 MAPKAPK2 Affinity Capture-Western physical 11042204 AKT1 Biochemical Activity physical 11042204 EGFR Biochemical Activity physical 7535770 ATF2 Biochemical Activity physical 7535770 ATF2 Reconstituted Complex physical 7535770 SPAG9 Affinity Capture-Western physical 12391307 MEF2A Biochemical Activity physical 9858528 MEF2A Biochemical Activity physical 10330143 DUSP16 Affinity Capture-Western physical 11359773 DUSP16 Reconstituted Complex physical 11359773 DUSP10 Reconstituted Complex physical 11359773 DUSP6 Affinity Capture-Western physical 11359773 DUSP10 Affinity Capture-Western physical 11359773 DUSP16 Affinity Capture-Western physical 11359773 DUSP1 Affinity Capture-Western physical 11359773 CSNK2A1 Affinity Capture-Western physical 10747897 CSNK2A1 Reconstituted Complex physical 10747897 MAP2K6 Biochemical Activity physical 8622669 DYRK1B Biochemical Activity physical 10910078 CDC25B Biochemical Activity physical 11333986 CDC25C Biochemical Activity physical 11333986 CDC25B Reconstituted Complex physical 11333986 CDC25C Reconstituted Complex physical 11333986 DUSP16 Affinity Capture-Western physical 11489891 MAP2K6 Biochemical Activity physical 8626699 HTRA2 Affinity Capture-Western physical 10644717 GMFB Affinity Capture-Western physical 8798479 ETV1 Biochemical Activity physical 11551945 MAPKAPK2 Affinity Capture-Western physical 11551945 DUSP10 Biochemical Activity physical 10391943 MAPKAPK3 Affinity Capture-Western physical 11157753 MAPK1 Affinity Capture-Western physical 11157753 RPS6KA3 Affinity Capture-Western physical 11157753 MAPKAPK3 Reconstituted Complex physical 11157753 RPS6KA5 Affinity Capture-Western physical 11157753 MKNK1 Affinity Capture-Western physical 11157753 DUSP10 Affinity Capture-Western physical 11157753 TAB1 Reconstituted Complex physical 11847341 TAB1 Affinity Capture-Western physical 11847341 MAPK14 Biochemical Activity physical 11847341 DUSP4 Reconstituted Complex physical 11387337 DUSP1 Two-hybrid physical 11278799 DUSP1 Affinity Capture-Western physical 11278799 ATF2 Biochemical Activity physical 11279118 MAP2K3 Biochemical Activity physical 11279118 MAP2K6 Biochemical Activity physical 11279118 PLCB2 Affinity Capture-Western physical 12054652 MAP2K7 Biochemical Activity physical 9207092 DDIT3 Biochemical Activity physical 8650547 ATF2 Biochemical Activity physical 9207092 KRT8 Biochemical Activity physical 11788583 KRT8 Reconstituted Complex physical 11788583 TGFBR1 Affinity Capture-Western physical 18758450 CAMKK2 Affinity Capture-MS physical 20562859 AES Two-hybrid physical 20936779 DUSP1 Two-hybrid physical 20936779 FLNA Two-hybrid physical 20936779 MKNK2 Two-hybrid physical 20936779 HIVEP1 Two-hybrid physical 20936779 MEF2C Two-hybrid physical 20936779 MEF2D Two-hybrid physical 20936779 NKTR Two-hybrid physical 20936779 ROBO1 Two-hybrid physical 20936779 SPTBN1 Two-hybrid physical 20936779 TCF20 Two-hybrid physical 20936779 ZNF142 Two-hybrid physical 20936779 MAPKAPK5 Two-hybrid physical 20936779 MKNK1 Two-hybrid physical 20936779 RPS6KA5 Two-hybrid physical 20936779 DUSP10 Two-hybrid physical 20936779 YY1AP1 Two-hybrid physical 20936779 FAM48A Two-hybrid physical 20936779 SMEK1 Two-hybrid physical 20936779 MLL3 Two-hybrid physical 20936779 CCDC14 Two-hybrid physical 20936779 MOBKL2B Two-hybrid physical 20936779 DUSP16 Two-hybrid physical 20936779 CCDC97 Two-hybrid physical 20936779 C14orf43 Two-hybrid physical 20936779 DDX26B Two-hybrid physical 20936779 MUC12 Two-hybrid physical 20936779 BAZ1B Biochemical Activity physical 19776015 PI4K2B Biochemical Activity physical 16949365 TFCP2 Biochemical Activity physical 15857981 SP1 Affinity Capture-Western physical 18419748 MYEF2 Affinity Capture-Western physical 15111488 CD4 Biochemical Activity physical 20530479 MAP2K3 Affinity Capture-Western physical 17255949 MAP2K6 Affinity Capture-Western physical 17255949 ZNHIT1 Biochemical Activity physical 17380123 GDF15 Two-hybrid physical 18624398 SRSF5 Two-hybrid physical 18624398 ZNHIT1 Two-hybrid physical 18624398 CENPC1 Two-hybrid physical 18624398 COPS5 Two-hybrid physical 18624398 EEF1A1 Two-hybrid physical 18624398 EPB42 Two-hybrid physical 18624398 RPL22 Two-hybrid physical 18624398 RPL41 Two-hybrid physical 18624398 SNAPIN Two-hybrid physical 18624398 CSNK2B Affinity Capture-Western physical 20797629 NFKBIA Affinity Capture-Western physical 20797629 IKBKB Affinity Capture-Western physical 20797629 NFKBIA Affinity Capture-Western physical 20797629 CSNK2B Affinity Capture-Western physical 20797629 BTRC Affinity Capture-Western physical 20797629 IKBKB Affinity Capture-Western physical 20797629 PAK6 Two-hybrid physical 21900206 RELA Two-hybrid physical 21900206 MAPK11 Two-hybrid physical 21900206 TAB1 Two-hybrid physical 21900206 NCOA3 Biochemical Activity physical 15383283