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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for DTX1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006351 transcription, DNA-dependent NAS GO:0006366 transcription from RNA polymerase II promoter TAS GO:0007166 cell surface receptor linked signaling pathway TAS GO:0008593 regulation of Notch signaling pathway IGI GO:0010001 glial cell differentiation IEA GO:0045581 negative regulation of T cell differentiation IEA GO:0045665 negative regulation of neuron differentiation IGI cellular_component GO:0005634 nucleus IEA GO:0005737 cytoplasm IEA molecular_function GO:0003713 transcription coactivator activity TAS GO:0005112 Notch binding IDA GO:0005515 protein binding IPI GO:0008270 zinc ion binding IEA GO:0017124 SH3 domain binding IEA GO:0031625 ubiquitin protein ligase binding IPI GO:0046872 metal ion binding IEA

Protein-protein interaction details for DTX1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID DTX3L Affinity Capture-Western physical 12670957 NOTCH1 Affinity Capture-Western physical 11564735 DTX1 Affinity Capture-Western physical 11564735 EP300 Affinity Capture-Western physical 11564735 EP300 Two-hybrid physical 11564735 GRB2 Two-hybrid physical 9590294 ITCH Reconstituted Complex physical 18628966 UBE2C Two-hybrid physical 19690564 UBE2D1 Two-hybrid physical 19690564 UBE2D2 Two-hybrid physical 19690564 UBE2D3 Two-hybrid physical 19690564 UBE2D4 Two-hybrid physical 19690564 UBE2E1 Two-hybrid physical 19690564 UBE2N Two-hybrid physical 19690564 UBE2U Two-hybrid physical 19690564 MAP3K1 Affinity Capture-Western physical 15684388 MAP3K1 Reconstituted Complex physical 15684388 NOTCH1 Affinity Capture-Western physical 20208568