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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for DVL1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001505 regulation of neurotransmitter levels ISS GO:0006366 transcription from RNA polymerase II promoter IDA GO:0006469 negative regulation of protein kinase activity IDA GO:0007269 neurotransmitter secretion ISS GO:0007275 multicellular organismal development IEA GO:0007411 axon guidance IBA GO:0007528 neuromuscular junction development ISS GO:0021915 neural tube development IEP GO:0030177 positive regulation of Wnt receptor signaling pathway IDA GO:0032091 negative regulation of protein binding IDA GO:0034504 protein localization to nucleus IMP GO:0035556 intracellular signal transduction IEA GO:0043113 receptor clustering ISS GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0048668 collateral sprouting IBA GO:0048675 axon extension IBA GO:0048813 dendrite morphogenesis IBA GO:0048813 dendrite morphogenesis ISS GO:0050808 synapse organization ISS GO:0060026 convergent extension IBA GO:0060070 canonical Wnt receptor signaling pathway IDA GO:0060071 Wnt receptor signaling pathway, planar cell polarity pathway IDA GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering IBA GO:0090103 cochlea morphogenesis IBA GO:0090179 planar cell polarity pathway involved in neural tube closure IBA cellular_component GO:0005737 cytoplasm IEA GO:0005829 cytosol IEA GO:0005874 microtubule IBA GO:0005886 plasma membrane IEA GO:0005938 cell cortex IBA GO:0016023 cytoplasmic membrane-bounded vesicle ISS GO:0019717 synaptosome ISS GO:0030136 clathrin-coated vesicle IBA GO:0030424 axon IBA GO:0030425 dendrite IBA GO:0030426 growth cone IBA GO:0031410 cytoplasmic vesicle IDA GO:0043025 neuronal cell body IBA GO:0045202 synapse IBA GO:0045202 synapse ISS molecular_function GO:0004871 signal transducer activity IEA GO:0005109 frizzled binding IPI GO:0005515 protein binding IPI GO:0019899 enzyme binding IPI GO:0019901 protein kinase binding IPI GO:0042802 identical protein binding IPI GO:0048365 Rac GTPase binding IBA

Protein-protein interaction details for DVL1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID EPS8 Two-hybrid physical 10581192 HECW1 Two-hybrid physical 14684739 HECW1 Affinity Capture-Western physical 14684739 DAB2 Reconstituted Complex physical 12805222 SMAD3 Two-hybrid physical 12650946 SMAD1 Reconstituted Complex physical 12650946 SMAD2 Reconstituted Complex physical 12650946 SMAD3 Reconstituted Complex physical 12650946 SMAD4 Reconstituted Complex physical 12650946 SMAD7 Reconstituted Complex physical 12650946 CSNK2A1 Affinity Capture-Western physical 10806215 CTNNB1 Affinity Capture-Western physical 10806215 USP13 Two-hybrid physical 16169070 ARRB1 Affinity Capture-Western physical 11742073 AXIN1 Affinity Capture-Western physical 10428961 FRAT1 Affinity Capture-Western physical 10428961 EPS8 Reconstituted Complex physical 10581192 EPS8 Affinity Capture-Western physical 10581192 ATN1 Two-hybrid physical 10332026 DVL3 Two-hybrid physical 10330181 DVL3 Affinity Capture-Western physical 10330181 DVL3 Reconstituted Complex physical 10330181 DVL1 Affinity Capture-Western physical 10330181 CSNK1D Affinity Capture-Western physical 11818547 CSNK1E Affinity Capture-Western physical 11818547 AXIN1 Affinity Capture-Western physical 18632848 SIRT1 Affinity Capture-Western physical 20439735 UBC Affinity Capture-Western physical 20227366 CYLD Affinity Capture-Western physical 20227366 UBC Affinity Capture-Western physical 20227366 NKD2 Affinity Capture-Western physical 20177058 NKD2 Co-fractionation physical 20177058 SDC4 Affinity Capture-Western physical 20639201 ANXA7 Two-hybrid physical 21900206