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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for E4F1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IDA GO:0006260 DNA replication IEA GO:0006351 transcription, DNA-dependent TAS GO:0006355 regulation of transcription, DNA-dependent TAS GO:0007049 cell cycle IEA GO:0007067 mitosis IEA GO:0008283 cell proliferation TAS GO:0009790 embryo development IEA GO:0009794 regulation of mitotic cell cycle, embryonic IEA GO:0010564 regulation of cell cycle process IDA GO:0040008 regulation of growth IEA GO:0044419 interspecies interaction between organisms IEA GO:0051301 cell division IEA GO:0071850 mitotic cell cycle arrest TAS cellular_component GO:0005622 intracellular IEA GO:0005634 nucleus IEA GO:0005654 nucleoplasm IEA GO:0005737 cytoplasm IEA GO:0005819 spindle IEA molecular_function GO:0003676 nucleic acid binding IEA GO:0003677 DNA binding IEA GO:0003700 sequence-specific DNA binding transcription factor activity TAS GO:0003713 transcription coactivator activity TAS GO:0003714 transcription corepressor activity TAS GO:0005515 protein binding IPI GO:0008270 zinc ion binding IEA GO:0016874 ligase activity IEA GO:0035497 cAMP response element binding IDA GO:0046872 metal ion binding IEA

Protein-protein interaction details for E4F1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID EHMT2 Two-hybrid physical 16189514 ATM Protein-peptide physical 10608806 ATR Protein-peptide physical 10608806 PRKDC Protein-peptide physical 10608806 CDKN2A Two-hybrid physical 12446718 CDKN2A Affinity Capture-Western physical 12446718 TP53 Affinity Capture-Western physical 12446718 RB1 Two-hybrid physical 10869426 RB1 Reconstituted Complex physical 10869426 RB1 Affinity Capture-Western physical 10869426 TP53 Two-hybrid physical 10644996 TP53 Reconstituted Complex physical 10644996 TP53 Affinity Capture-Western physical 10644996 HDAC1 Affinity Capture-Western physical 12730668 HDAC1 Reconstituted Complex physical 12730668 HDAC1 Affinity Capture-Western physical 12730668