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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ELANE (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001878response to yeastIEA
GO:0002438acute inflammatory response to antigenic stimulusIEA
GO:0006508proteolysisIDA
GO:0006874cellular calcium ion homeostasisNAS
GO:0006909phagocytosisIEA
GO:0009411response to UVIDA
GO:0030163protein catabolic processNAS
GO:0032496response to lipopolysaccharideIEA
GO:0043406positive regulation of MAP kinase activityNAS
GO:0044130negative regulation of growth of symbiont in hostIEA
GO:0045079negative regulation of chemokine biosynthetic processIDA
GO:0045415negative regulation of interleukin-8 biosynthetic processIDA
GO:0045416positive regulation of interleukin-8 biosynthetic processIDA
GO:0048661positive regulation of smooth muscle cell proliferationIDA
GO:0050728negative regulation of inflammatory responseNAS
GO:0050778positive regulation of immune responseIEA
GO:0050900leukocyte migrationIEA
GO:0050922negative regulation of chemotaxisNAS
GO:0070947neutrophil mediated killing of fungusIEA
cellular_component
GO:0005576extracellular regionNAS
GO:0005737cytoplasmIEA
GO:0009986cell surfaceIDA
GO:0030141stored secretory granuleIDA
molecular_function
GO:0004175endopeptidase activityIDA
GO:0004252serine-type endopeptidase activityIEA
GO:0005515protein bindingIPI
GO:0008201heparin bindingIDA
GO:0008233peptidase activityIDA
GO:0019955cytokine bindingIPI
GO:0051635bacterial cell surface bindingNAS

Protein-protein interaction details for ELANE (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
NOTCH2NLTwo-hybridphysical14673143
NOTCH2NLAffinity Capture-Westernphysical14673143
NOTCH2NLReconstituted Complexphysical14673143
SERPINA3Biochemical Activityphysical8718849
SERPINF2Biochemical Activityphysical6980881
SERPING1Biochemical Activityphysical6980881
SERPINA1Reconstituted Complexphysical10867014
THBS1Reconstituted Complexphysical8463250
SERPINB1Biochemical Activityphysical10924364
SERPINF2Biochemical Activityphysical2437112
KNG1Biochemical Activityphysical12887060