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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ENG (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IDA GO:0001300 chronological cell aging IEP GO:0001569 patterning of blood vessels IEA GO:0001569 patterning of blood vessels ISS GO:0001570 vasculogenesis IEA GO:0001570 vasculogenesis IMP GO:0001666 response to hypoxia IDA GO:0001934 positive regulation of protein phosphorylation IDA GO:0001937 negative regulation of endothelial cell proliferation IMP GO:0001947 heart looping IEA GO:0001947 heart looping ISS GO:0003084 positive regulation of systemic arterial blood pressure IMP GO:0006355 regulation of transcription, DNA-dependent IMP GO:0007155 cell adhesion IEA GO:0007179 transforming growth factor beta receptor signaling pathway IDA GO:0007507 heart development IEA GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IDA GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IMP GO:0016477 cell migration IMP GO:0017015 regulation of transforming growth factor beta receptor signaling pathway IDA GO:0022009 central nervous system vasculogenesis IMP GO:0022617 extracellular matrix disassembly IMP GO:0030155 regulation of cell adhesion TAS GO:0030509 BMP signaling pathway TAS GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway TAS GO:0030513 positive regulation of BMP signaling pathway IDA GO:0031953 negative regulation of protein autophosphorylation IDA GO:0042060 wound healing IMP GO:0042127 regulation of cell proliferation TAS GO:0042325 regulation of phosphorylation TAS GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0048745 smooth muscle tissue development IEA GO:0048745 smooth muscle tissue development ISS GO:0048844 artery morphogenesis IEA GO:0048844 artery morphogenesis ISS GO:0048845 venous blood vessel morphogenesis IEA GO:0048845 venous blood vessel morphogenesis ISS GO:0048870 cell motility IMP GO:0051001 negative regulation of nitric-oxide synthase activity IMP GO:0060326 cell chemotaxis IMP GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation IMP GO:0070483 detection of hypoxia IDA cellular_component GO:0005615 extracellular space IDA GO:0005624 membrane fraction IDA GO:0009897 external side of plasma membrane IDA GO:0009986 cell surface IDA GO:0016020 membrane IEA GO:0016021 integral to membrane IEA GO:0070022 transforming growth factor beta receptor complex IC GO:0072563 endothelial microparticle IEA molecular_function GO:0004888 transmembrane signaling receptor activity NAS GO:0005024 transforming growth factor beta-activated receptor activity IDA GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity IDA GO:0005114 type II transforming growth factor beta receptor binding IPI GO:0005114 type II transforming growth factor beta receptor binding ISS GO:0005515 protein binding IPI GO:0005534 galactose binding IDA GO:0005539 glycosaminoglycan binding IDA GO:0005539 glycosaminoglycan binding ISS GO:0034713 type I transforming growth factor beta receptor binding IPI GO:0034713 type I transforming growth factor beta receptor binding ISS GO:0042803 protein homodimerization activity IPI GO:0048185 activin binding TAS GO:0050431 transforming growth factor beta binding IPI

Protein-protein interaction details for ENG (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID TGFBR2 Affinity Capture-Western physical 12015308 TGFBR1 Affinity Capture-Western physical 12015308 TGFBR1 Affinity Capture-Western physical 12015308 TGFBR2 Affinity Capture-Western physical 12015308 TGFBR1 Biochemical Activity physical 12015308 TGFBR2 Biochemical Activity physical 12015308 TGFBR2 Affinity Capture-Western physical 9872992 TGFBR1 Affinity Capture-Western physical 9872992 TGFBR2 Affinity Capture-Western physical 9872992 ACVR1 Affinity Capture-Western physical 9872992 ACVR2B Affinity Capture-Western physical 9872992 BMP7 Affinity Capture-Western physical 9872992 BMP2 Affinity Capture-Western physical 9872992 ACVR2A Affinity Capture-Western physical 9872992