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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ERN1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006355 regulation of transcription, DNA-dependent IEA GO:0006397 mRNA processing IEA GO:0006468 protein phosphorylation IDA GO:0006915 apoptosis IEA GO:0006917 induction of apoptosis ISS GO:0006986 response to unfolded protein IEA GO:0006987 activation of signaling protein activity involved in unfolded protein response IDA GO:0007050 cell cycle arrest ISS GO:0046777 protein autophosphorylation IEA cellular_component GO:0005783 endoplasmic reticulum IEA GO:0005789 endoplasmic reticulum membrane TAS GO:0016020 membrane IEA GO:0016021 integral to membrane IEA GO:0030176 integral to endoplasmic reticulum membrane IDA molecular_function GO:0000166 nucleotide binding IEA GO:0000287 magnesium ion binding IDA GO:0004521 endoribonuclease activity IDA GO:0004521 endoribonuclease activity TAS GO:0004674 protein serine/threonine kinase activity IDA GO:0004674 protein serine/threonine kinase activity TAS GO:0005524 ATP binding IDA GO:0016787 hydrolase activity IEA GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters IEA

Protein-protein interaction details for ERN1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID TRAF2 Affinity Capture-Western physical 12843613 ERN1 Reconstituted Complex physical 12637535 HSPA5 Reconstituted Complex physical 12637535 MAP3K5 Affinity Capture-Western physical 12050113 HSP90AA1 Affinity Capture-Western physical 12446770 HSP90AA1 Reconstituted Complex physical 12446770 TAOK3 Affinity Capture-Western physical 11278723 PSEN1 Affinity Capture-Western physical 10587643 SYVN1 Affinity Capture-Western physical 18369366 UBC Affinity Capture-Western physical 18369366