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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for F2R (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000186 activation of MAPKK activity IEA GO:0002248 connective tissue replacement involved in inflammatory response wound healing IDA GO:0006919 activation of caspase activity IDA GO:0006954 inflammatory response IEA GO:0007186 G-protein coupled receptor protein signaling pathway ISS GO:0007186 G-protein coupled receptor protein signaling pathway TAS GO:0007204 elevation of cytosolic calcium ion concentration ISS GO:0007205 activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway IEA GO:0007260 tyrosine phosphorylation of STAT protein IDA GO:0007262 STAT protein import into nucleus IDA GO:0007529 establishment of synaptic specificity at neuromuscular junction IEA GO:0007596 blood coagulation TAS GO:0008284 positive regulation of cell proliferation IEA GO:0008285 negative regulation of cell proliferation IDA GO:0009611 response to wounding IDA GO:0009653 anatomical structure morphogenesis TAS GO:0014068 positive regulation of phosphatidylinositol 3-kinase cascade ISS GO:0016265 death IEA GO:0030168 platelet activation IDA GO:0030168 platelet activation TAS GO:0030193 regulation of blood coagulation IDA GO:0030194 positive regulation of blood coagulation IDA GO:0030335 positive regulation of cell migration IMP GO:0032496 response to lipopolysaccharide IEA GO:0032651 regulation of interleukin-1 beta production IEA GO:0032967 positive regulation of collagen biosynthetic process IDA GO:0035025 positive regulation of Rho protein signal transduction ISS GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IEP GO:0043280 positive regulation of caspase activity IDA GO:0043410 positive regulation of MAPKKK cascade IDA GO:0043524 negative regulation of neuron apoptosis IEA GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045907 positive regulation of vasoconstriction IEA GO:0045987 positive regulation of smooth muscle contraction IEA GO:0046427 positive regulation of JAK-STAT cascade IDA GO:0048873 homeostasis of number of cells within a tissue IEA GO:0051281 positive regulation of release of sequestered calcium ion into cytosol IDA GO:0051482 elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger IEA GO:0051928 positive regulation of calcium ion transport IEA GO:0051930 regulation of sensory perception of pain IEA GO:0060155 platelet dense granule organization IC GO:0070374 positive regulation of ERK1 and ERK2 cascade ISS GO:0070493 thrombin receptor signaling pathway IDA GO:0070493 thrombin receptor signaling pathway TAS GO:2000484 positive regulation of interleukin-8 secretion IDA GO:2000778 positive regulation of interleukin-6 secretion IDA cellular_component GO:0005576 extracellular region TAS GO:0005794 Golgi apparatus TAS GO:0005886 plasma membrane IDA GO:0005886 plasma membrane TAS GO:0005887 integral to plasma membrane TAS GO:0005901 caveola IDA GO:0031094 platelet dense tubular network IDA GO:0031594 neuromuscular junction IEA GO:0045211 postsynaptic membrane IEA molecular_function GO:0001965 G-protein alpha-subunit binding ISS GO:0004871 signal transducer activity IEA GO:0004872 receptor activity IEA GO:0004930 G-protein coupled receptor activity ISS GO:0004930 G-protein coupled receptor activity TAS GO:0005102 receptor binding IPI GO:0005515 protein binding IPI GO:0015057 thrombin receptor activity IDA GO:0031681 G-protein beta-subunit binding ISS

Protein-protein interaction details for F2R (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SNX1 Reconstituted Complex physical 12058063 SNX1 Affinity Capture-Western physical 12058063 GNA12 Affinity Capture-Western physical 8290554 GNA13 Affinity Capture-Western physical 8290554 UBC Affinity Capture-Western physical 21965661