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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for FGF2 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000186
activation of MAPKK activity
IEA
GO:0000187
activation of MAPK activity
TAS
GO:0000189
MAPK import into nucleus
IEA
GO:0001658
branching involved in ureteric bud morphogenesis
IDA
GO:0001759
organ induction
IEA
GO:0001934
positive regulation of protein phosphorylation
IEA
GO:0001938
positive regulation of endothelial cell proliferation
IMP
GO:0002042
cell migration involved in sprouting angiogenesis
IDA
GO:0002042
cell migration involved in sprouting angiogenesis
IGI
GO:0006661
phosphatidylinositol biosynthetic process
IDA
GO:0006700
C21-steroid hormone biosynthetic process
IEA
GO:0006915
apoptosis
IEA
GO:0006935
chemotaxis
TAS
GO:0007165
signal transduction
IEA
GO:0007243
intracellular protein kinase cascade
IEA
GO:0007265
Ras protein signal transduction
TAS
GO:0007268
synaptic transmission
IEA
GO:0007399
nervous system development
TAS
GO:0008284
positive regulation of cell proliferation
IGI
GO:0008285
negative regulation of cell proliferation
IEA
GO:0008286
insulin receptor signaling pathway
TAS
GO:0008543
fibroblast growth factor receptor signaling pathway
IDA
GO:0008543
fibroblast growth factor receptor signaling pathway
IGI
GO:0008543
fibroblast growth factor receptor signaling pathway
IPI
GO:0008543
fibroblast growth factor receptor signaling pathway
TAS
GO:0009887
organ morphogenesis
TAS
GO:0010001
glial cell differentiation
IEA
GO:0010863
positive regulation of phospholipase C activity
IDA
GO:0017158
regulation of calcium ion-dependent exocytosis
IEA
GO:0021762
substantia nigra development
IEA
GO:0021940
positive regulation of cerebellar granule cell precursor proliferation
IEA
GO:0030308
negative regulation of cell growth
IEA
GO:0030324
lung development
IEA
GO:0032958
inositol phosphate biosynthetic process
IDA
GO:0042060
wound healing
TAS
GO:0042660
positive regulation of cell fate specification
IDA
GO:0043536
positive regulation of blood vessel endothelial cell migration
IDA
GO:0043537
negative regulation of blood vessel endothelial cell migration
IDA
GO:0043552
positive regulation of phosphatidylinositol 3-kinase activity
IDA
GO:0045669
positive regulation of osteoblast differentiation
IEA
GO:0045765
regulation of angiogenesis
TAS
GO:0045766
positive regulation of angiogenesis
IDA
GO:0045892
negative regulation of transcription, DNA-dependent
IEA
GO:0045893
positive regulation of transcription, DNA-dependent
IDA
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IDA
GO:0046668
regulation of retinal cell programmed cell death
IEA
GO:0048598
embryonic morphogenesis
TAS
GO:0048678
response to axon injury
IEA
GO:0048864
stem cell development
IEA
GO:0050918
positive chemotaxis
IDA
GO:0051209
release of sequestered calcium ion into cytosol
IDA
GO:0051726
regulation of cell cycle
IEA
GO:0051781
positive regulation of cell division
IEA
GO:0060045
positive regulation of cardiac muscle cell proliferation
IDA
GO:0060128
corticotropin hormone secreting cell differentiation
IEA
GO:0060129
thyroid-stimulating hormone-secreting cell differentiation
IEA
GO:0060548
negative regulation of cell death
IDA
GO:0060591
chondroblast differentiation
IDA
GO:0060644
mammary gland epithelial cell differentiation
IEA
GO:0070374
positive regulation of ERK1 and ERK2 cascade
IDA
cellular_component
GO:0005576
extracellular region
TAS
GO:0005615
extracellular space
IEA
GO:0005634
nucleus
IEA
GO:0005737
cytoplasm
IEA
molecular_function
GO:0004713
protein tyrosine kinase activity
TAS
GO:0005104
fibroblast growth factor receptor binding
IPI
GO:0005125
cytokine activity
IDA
GO:0005245
voltage-gated calcium channel activity
IEA
GO:0005515
protein binding
IPI
GO:0008083
growth factor activity
IDA
GO:0008201
heparin binding
IEA
GO:0017134
fibroblast growth factor binding
IEA
GO:0030374
ligand-dependent nuclear receptor transcription coactivator activity
IDA
GO:0042056
chemoattractant activity
IDA
Protein-protein interaction details for FGF2 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
SDC1
Co-purification
physical
16982797
SDC2
Co-purification
physical
16982797
SDC4
Co-purification
physical
16982797
CSNK2A1
Reconstituted Complex
physical
12145206
CSNK2A2
Reconstituted Complex
physical
12145206
CSNK2B
Reconstituted Complex
physical
12145206
CSNK2A1
Biochemical Activity
physical
12145206
GPC3
Affinity Capture-Western
physical
12478660
RPS19
Co-purification
physical
11716516
RPS19
Reconstituted Complex
physical
11716516
VTN
Reconstituted Complex
physical
11796824
FGFBP1
Reconstituted Complex
physical
11509569
SDC3
Reconstituted Complex
physical
8344959
FGFR1
Reconstituted Complex
physical
10950949
GPC4
Reconstituted Complex
physical
11066092
RPL6
Two-hybrid
physical
9826564
RPL6
Reconstituted Complex
physical
9826564