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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for FGFR3 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000165 MAPKKK cascade TAS GO:0001501 skeletal system development TAS GO:0001958 endochondral ossification TAS GO:0002062 chondrocyte differentiation TAS GO:0003416 endochondral bone growth TAS GO:0007259 JAK-STAT cascade TAS GO:0008284 positive regulation of cell proliferation IEA GO:0008284 positive regulation of cell proliferation IGI GO:0008284 positive regulation of cell proliferation IMP GO:0008286 insulin receptor signaling pathway TAS GO:0008543 fibroblast growth factor receptor signaling pathway IDA GO:0008543 fibroblast growth factor receptor signaling pathway IGI GO:0008543 fibroblast growth factor receptor signaling pathway IMP GO:0008543 fibroblast growth factor receptor signaling pathway TAS GO:0010518 positive regulation of phospholipase activity IMP GO:0018108 peptidyl-tyrosine phosphorylation IDA GO:0035988 chondrocyte proliferation TAS GO:0042511 positive regulation of tyrosine phosphorylation of Stat1 protein IMP GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein IMP GO:0042981 regulation of apoptosis IMP GO:0043410 positive regulation of MAPKKK cascade IMP GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity IMP GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity TAS GO:0046777 protein autophosphorylation IDA GO:0048640 negative regulation of developmental growth ISS GO:0060349 bone morphogenesis TAS GO:0070374 positive regulation of ERK1 and ERK2 cascade IMP GO:0070977 bone maturation ISS cellular_component GO:0005886 plasma membrane TAS GO:0005887 integral to plasma membrane IDA GO:0005925 focal adhesion TAS GO:0016021 integral to membrane IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004713 protein tyrosine kinase activity IDA GO:0004713 protein tyrosine kinase activity IEA GO:0004713 protein tyrosine kinase activity TAS GO:0004872 receptor activity IEA GO:0005007 fibroblast growth factor-activated receptor activity IEA GO:0005007 fibroblast growth factor-activated receptor activity IMP GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016772 transferase activity, transferring phosphorus-containing groups IEA GO:0017134 fibroblast growth factor binding IDA GO:0017134 fibroblast growth factor binding IPI

Protein-protein interaction details for FGFR3 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID C6orf47 Two-hybrid physical 14667819 SMG7 Two-hybrid physical 16169070 C13orf34 Two-hybrid physical 16169070 CCDC17 Two-hybrid physical 16169070 HBZ Two-hybrid physical 16169070 HNRNPL Two-hybrid physical 16169070 NDUFS6 Two-hybrid physical 16169070 RNF130 Two-hybrid physical 16169070 ATF3 Two-hybrid physical 16169070 ARAP1 Two-hybrid physical 16169070 CHGB Two-hybrid physical 16169070 CTSK Two-hybrid physical 16169070 RADIL Two-hybrid physical 16169070 GTF3C1 Two-hybrid physical 16169070 KRT8 Two-hybrid physical 16169070 POLA2 Two-hybrid physical 16169070 KIAA1377 Two-hybrid physical 16169070 RPL8 Two-hybrid physical 16169070 SLC25A6 Two-hybrid physical 16169070 SH2B1 Affinity Capture-Western physical 11827956 FGF9 Reconstituted Complex physical 8576175 FGF1 Reconstituted Complex physical 8576175 GRB2 Affinity Capture-Western physical 9045692 FGF9 Affinity Capture-Western physical 10574949 FGF8 Affinity Capture-Western physical 10574949 FGF9 Reconstituted Complex physical 10574949 FGF1 Reconstituted Complex physical 10574949 HSP90AA1 Affinity Capture-MS physical 21487019 HSP90AB1 Affinity Capture-MS physical 21487019 HSPA1B Affinity Capture-MS physical 21487019 HSPA8 Affinity Capture-MS physical 21487019 CDC37 Affinity Capture-MS physical 21487019 HSP90AB1 Affinity Capture-Western physical 21487019 CDC37 Affinity Capture-Western physical 21487019 HSP90AB1 Affinity Capture-Western physical 21487019 CDC37 Affinity Capture-Western physical 21487019 HSPA4 Affinity Capture-Western physical 21487019