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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PAXIP1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000416 positive regulation of histone H3-K36 methylation ISS GO:0006281 DNA repair IEA GO:0006310 DNA recombination IEA GO:0006355 regulation of transcription, DNA-dependent IEA GO:0010212 response to ionizing radiation IDA GO:0030330 DNA damage response, signal transduction by p53 class mediator IMP GO:0031398 positive regulation of protein ubiquitination ISS GO:0035066 positive regulation of histone acetylation ISS GO:0045830 positive regulation of isotype switching ISS GO:0051568 histone H3-K4 methylation IDA GO:0051571 positive regulation of histone H3-K4 methylation ISS GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter IMP GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter ISS cellular_component GO:0005622 intracellular IEA GO:0005634 nucleus IDA GO:0016363 nuclear matrix IEA GO:0035097 histone methyltransferase complex IDA molecular_function GO:0005515 protein binding IPI

Protein-protein interaction details for PAXIP1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ZBTB8A Two-hybrid physical 16189514 TP53BP1 Affinity Capture-Western physical 15456759 TP53BP1 Affinity Capture-Western physical 15456759 TP53BP1 Reconstituted Complex physical 14576432 PAX2 Two-hybrid physical 10908331 PAX2 Affinity Capture-Western physical 10908331 PAX2 Affinity Capture-Western physical 10908331 PAX2 Reconstituted Complex physical 10908331 KDM6A Affinity Capture-MS physical 17761849 C16orf53 Affinity Capture-Western physical 19124460 NCOA6 Affinity Capture-MS physical 19047629 SRRM1 Affinity Capture-MS physical 16159877 MLL2 Affinity Capture-MS physical 17925232 MLL3 Affinity Capture-MS physical 17925232 TP53BP1 Affinity Capture-MS physical 17925232 KDM6A Affinity Capture-MS physical 17925232 SMC1A Affinity Capture-MS physical 17925232 SMC3 Affinity Capture-MS physical 17925232 RAD50 Affinity Capture-MS physical 17925232 PAXIP1 Affinity Capture-MS physical 17925232 ASH2L Affinity Capture-MS physical 17925232 RBBP5 Affinity Capture-MS physical 17925232 PRMT5 Affinity Capture-MS physical 17925232 WDR5 Affinity Capture-MS physical 17925232 ASH2L Affinity Capture-Western physical 17925232 ASH2L Affinity Capture-Western physical 17925232 RBBP5 Affinity Capture-Western physical 17925232 MLL2 Affinity Capture-Western physical 17925232 WDR5 Affinity Capture-Western physical 17925232 NCOA6 Affinity Capture-Western physical 17925232 NCOA6 Affinity Capture-Western physical 17925232 RBBP5 Affinity Capture-Western physical 17925232 HIST1H3A Biochemical Activity physical 17925232 MLL4 Affinity Capture-MS physical 17500065 MLL3 Affinity Capture-MS physical 17500065 TP53BP1 Affinity Capture-MS physical 17500065 NCOA6 Affinity Capture-MS physical 17500065 BLM Affinity Capture-MS physical 17500065 RAD50 Affinity Capture-MS physical 17500065 MRE11A Affinity Capture-MS physical 17500065 ASH2L Affinity Capture-MS physical 17500065 RBBP5 Affinity Capture-MS physical 17500065 C16orf53 Affinity Capture-MS physical 17500065 WDR5 Affinity Capture-MS physical 17500065 DPY30 Affinity Capture-MS physical 17500065 MLL4 Affinity Capture-Western physical 17500065 MLL3 Affinity Capture-Western physical 17500065 TP53BP1 Affinity Capture-Western physical 17500065 NCOA6 Affinity Capture-Western physical 17500065 NBN Affinity Capture-Western physical 17500065 RAD50 Affinity Capture-Western physical 17500065 MRE11A Affinity Capture-Western physical 17500065 ASH2L Affinity Capture-Western physical 17500065 RBBP5 Affinity Capture-Western physical 17500065 C16orf53 Affinity Capture-Western physical 17500065 WDR5 Affinity Capture-Western physical 17500065 ASH2L Co-purification physical 17500065 WDR5 Co-purification physical 17500065 DPY30 Co-purification physical 17500065 RBBP5 Co-purification physical 17500065 MLL4 Co-purification physical 17500065 MLL3 Co-purification physical 17500065 NCOA6 Co-purification physical 17500065 C16orf53 Co-purification physical 17500065 ASH2L Affinity Capture-Western physical 17500065 RBBP5 Affinity Capture-Western physical 17500065 NCOA6 Affinity Capture-Western physical 17500065 WDR5 Affinity Capture-Western physical 17500065 C16orf53 Affinity Capture-Western physical 17500065 MLL3 Affinity Capture-Western physical 17500065 MLL4 Affinity Capture-Western physical 17500065 KDM6A Affinity Capture-Western physical 17500065 KDM1B Affinity Capture-MS physical 20670891 WDR82 Affinity Capture-MS physical 20516061 WDR82 Affinity Capture-Western physical 20516061 EP300 Reconstituted Complex physical 11940591