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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for BACE1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006508proteolysisIDA
GO:0006508proteolysisIEA
GO:0006509membrane protein ectodomain proteolysisTAS
GO:0050435beta-amyloid metabolic processIDA
cellular_component
GO:0005624membrane fractionIEA
GO:0005768endosomeIDA
GO:0005783endoplasmic reticulumIEA
GO:0005794Golgi apparatusIDA
GO:0005802trans-Golgi networkIDA
GO:0005887integral to plasma membraneIDA
GO:0009986cell surfaceIEA
GO:0016020membraneIEA
GO:0016021integral to membraneNAS
GO:0030424axonIEA
GO:0030659cytoplasmic vesicle membraneIEA
GO:0031410cytoplasmic vesicleIEA
molecular_function
GO:0004190aspartic-type endopeptidase activityIDA
GO:0004190aspartic-type endopeptidase activityIEA
GO:0008233peptidase activityIEA
GO:0008798beta-aspartyl-peptidase activityTAS
GO:0019899enzyme bindingIPI

Protein-protein interaction details for BACE1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
NCSTNReconstituted Complexphysical12054507
FBXO2Affinity Capture-Westernphysical20854419
FBXO2Biochemical Activityphysical20854419