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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NR5A1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001553 luteinization IEA GO:0007267 cell-cell signaling TAS GO:0007538 primary sex determination TAS GO:0008584 male gonad development TAS GO:0009888 tissue development IEA GO:0010467 gene expression TAS GO:0030154 cell differentiation IEA GO:0030325 adrenal gland development IEA GO:0030522 intracellular receptor mediated signaling pathway TAS GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor TAS GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IMP GO:0050810 regulation of steroid biosynthetic process TAS GO:0051457 maintenance of protein location in nucleus IEA GO:2000020 positive regulation of male gonad development IDA GO:2000020 positive regulation of male gonad development IEA GO:2000195 negative regulation of female gonad development IEA cellular_component GO:0005634 nucleus IDA GO:0005654 nucleoplasm TAS molecular_function GO:0003677 DNA binding IDA GO:0003682 chromatin binding IEA GO:0003690 double-stranded DNA binding IEA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0003705 sequence-specific distal enhancer binding RNA polymerase II transcription factor activity IDA GO:0003707 steroid hormone receptor activity IEA GO:0003713 transcription coactivator activity TAS GO:0004872 receptor activity IEA GO:0004879 ligand-dependent nuclear receptor activity TAS GO:0005515 protein binding IPI GO:0005543 phospholipid binding IDA GO:0008270 zinc ion binding IEA GO:0019899 enzyme binding IPI GO:0043565 sequence-specific DNA binding IEA GO:0046872 metal ion binding IEA

Protein-protein interaction details for NR5A1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SOX9 Two-hybrid physical 9774680 NRIP1 Two-hybrid physical 12782406 NRIP1 Two-hybrid physical 11459805 ZNF653 Two-hybrid physical 12920234 ZNF653 Reconstituted Complex physical 12920234 CTNNB1 Affinity Capture-Western physical 12861022 NRIP1 Reconstituted Complex physical 12782406 GATA4 Reconstituted Complex physical 10446911 NR0B1 Reconstituted Complex physical 11713202 NR0B1 Two-hybrid physical 11713202 NCOA1 Two-hybrid physical 9328345 TRERF1 Reconstituted Complex physical 12101186 TRERF1 Affinity Capture-Western physical 12101186 TRERF1 Two-hybrid physical 12101186 CTNNB1 Two-hybrid physical 12554773 CTNNB1 Reconstituted Complex physical 12554773 SOX9 Reconstituted Complex physical 9774680 SOX9 Affinity Capture-Western physical 9774680 NRIP1 Reconstituted Complex physical 11459805 NR0B1 Reconstituted Complex physical 11459805 PITX1 Reconstituted Complex physical 10369682 JUN Reconstituted Complex physical 10478848 GTF2B Reconstituted Complex physical 10478848 SP1 Reconstituted Complex physical 10919277 SP1 Two-hybrid physical 10919277 EDF1 Affinity Capture-Western physical 10567391 CXXC1 Two-hybrid physical 20211142 CREBBP Reconstituted Complex physical 10628748 CTNNB1 Phenotypic Enhancement genetic 12861022 TCF7L2 Phenotypic Enhancement genetic 12861022