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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for GATA4 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001701 in utero embryonic development IEA GO:0001702 gastrulation with mouth forming second IEA GO:0001706 endoderm formation IEA GO:0001947 heart looping ISS GO:0003181 atrioventricular valve morphogenesis IEA GO:0003197 endocardial cushion development IEA GO:0003197 endocardial cushion development ISS GO:0003208 cardiac ventricle morphogenesis TAS GO:0003215 cardiac right ventricle morphogenesis ISS GO:0003229 ventricular cardiac muscle tissue development IEA GO:0003281 ventricular septum development ISS GO:0003289 atrial septum primum morphogenesis ISS GO:0003290 atrial septum secundum morphogenesis IMP GO:0006351 transcription, DNA-dependent IDA GO:0006355 regulation of transcription, DNA-dependent IDA GO:0006355 regulation of transcription, DNA-dependent ISS GO:0006366 transcription from RNA polymerase II promoter ISS GO:0007267 cell-cell signaling IEA GO:0007267 cell-cell signaling ISS GO:0007283 spermatogenesis IEA GO:0007492 endoderm development TAS GO:0007596 blood coagulation TAS GO:0008584 male gonad development IEP GO:0010575 positive regulation vascular endothelial growth factor production ISS GO:0023019 signal transduction involved in regulation of gene expression IEA GO:0030513 positive regulation of BMP signaling pathway IEA GO:0035054 embryonic heart tube anterior/posterior pattern specification IEA GO:0035054 embryonic heart tube anterior/posterior pattern specification ISS GO:0035239 tube morphogenesis IEA GO:0042493 response to drug IMP GO:0043627 response to estrogen stimulus IEA GO:0045766 positive regulation of angiogenesis ISS GO:0045893 positive regulation of transcription, DNA-dependent IEA GO:0045893 positive regulation of transcription, DNA-dependent ISS GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter ISS GO:0048557 embryonic digestive tract morphogenesis IEA GO:0048617 embryonic foregut morphogenesis IEA GO:0048617 embryonic foregut morphogenesis ISS GO:0051891 positive regulation of cardioblast differentiation ISS GO:0055007 cardiac muscle cell differentiation IEA GO:0055007 cardiac muscle cell differentiation IEP GO:0060008 Sertoli cell differentiation IEA GO:0060045 positive regulation of cardiac muscle cell proliferation IEA GO:0060070 canonical Wnt receptor signaling pathway IEA GO:0060395 SMAD protein signal transduction IEA GO:0060413 atrial septum morphogenesis IMP GO:0060464 lung lobe formation IEA GO:0060575 intestinal epithelial cell differentiation IDA GO:0071372 cellular response to follicle-stimulating hormone stimulus IEA GO:0072148 epithelial cell fate commitment IEA GO:0072520 seminiferous tubule development IEA cellular_component GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005634 nucleus ISS GO:0005634 nucleus NAS GO:0005654 nucleoplasm TAS molecular_function GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity IEA GO:0003677 DNA binding ISS GO:0003700 sequence-specific DNA binding transcription factor activity IDA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0005515 protein binding IPI GO:0008134 transcription factor binding IPI GO:0008270 zinc ion binding IEA GO:0033613 activating transcription factor binding IEA GO:0033613 activating transcription factor binding ISS GO:0043565 sequence-specific DNA binding IEA GO:0043565 sequence-specific DNA binding ISS GO:0044212 transcription regulatory region DNA binding IDA GO:0046872 metal ion binding IEA

Protein-protein interaction details for GATA4 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID MDC1 Protein-peptide physical 14578343 NKX2-5 Affinity Capture-Western physical 12845333 TBX5 Affinity Capture-Western physical 12845333 TBX5 Affinity Capture-Western physical 12845333 HAND2 Reconstituted Complex physical 11994297 HAND2 Affinity Capture-Western physical 11994297 NR5A1 Reconstituted Complex physical 10446911 ZFPM2 Two-hybrid physical 9927675 ZFPM2 Affinity Capture-Western physical 9927675 ZFPM2 Reconstituted Complex physical 9927675 SRF Affinity Capture-Western physical 11003651 SRF Reconstituted Complex physical 11003651 SRF Affinity Capture-Western physical 11158291 SRF Reconstituted Complex physical 11158291 MAPK1 Biochemical Activity physical 11585926 NKX2-5 Affinity Capture-Western physical 9312027 NKX2-5 Reconstituted Complex physical 9312027 NKX2-5 Reconstituted Complex physical 10948187 NKX2-5 Affinity Capture-Western physical 10948187 ID1 Affinity Capture-Western physical 16556596 ID2 Affinity Capture-Western physical 16556596 ID3 Affinity Capture-Western physical 16556596 ID1 Reconstituted Complex physical 16556596 ID2 Reconstituted Complex physical 16556596 ID3 Reconstituted Complex physical 16556596 ID2 Reconstituted Complex physical 16556596 ID3 Reconstituted Complex physical 16556596 ALX4 Two-hybrid physical 20211142 ZBTB3 Two-hybrid physical 20211142 EP300 Affinity Capture-Western physical 18252717 ZFPM2 Affinity Capture-Western physical 18252717 SP1 Affinity Capture-Western physical 14988427 SP1 Reconstituted Complex physical 14988427 HDAC2 Affinity Capture-Western physical 20833366 SP1 Reconstituted Complex physical 21184844