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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for GH1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002092positive regulation of receptor internalizationIDA
GO:0007259JAK-STAT cascadeIDA
GO:0010535positive regulation of activation of JAK2 kinase activityIDA
GO:0014068positive regulation of phosphatidylinositol 3-kinase cascadeIDA
GO:0015758glucose transportIDA
GO:0032355response to estradiol stimulusIDA
GO:0040018positive regulation of multicellular organism growthIDA
GO:0040018positive regulation of multicellular organism growthIMP
GO:0042517positive regulation of tyrosine phosphorylation of Stat3 proteinIDA
GO:0042523positive regulation of tyrosine phosphorylation of Stat5 proteinIDA
GO:0043406positive regulation of MAP kinase activityTAS
GO:0043568positive regulation of insulin-like growth factor receptor signaling pathwayIDA
GO:0046427positive regulation of JAK-STAT cascadeIDA
GO:0050731positive regulation of peptidyl-tyrosine phosphorylationIDA
GO:0060396growth hormone receptor signaling pathwayIDA
GO:0070977bone maturationIDA
cellular_component
GO:0005576extracellular regionIEA
GO:0005615extracellular spaceIDA
molecular_function
GO:0005131growth hormone receptor bindingIDA
GO:0005131growth hormone receptor bindingIPI
GO:0005148prolactin receptor bindingIPI
GO:0005179hormone activityIEA
GO:0005515protein bindingIPI
GO:0008083growth factor activityIPI
GO:0046872metal ion bindingIEA

Protein-protein interaction details for GH1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
LTA4HAffinity Capture-MSphysical17353931
STRAPAffinity Capture-MSphysical17353931
GHRReconstituted Complexphysical7862673
SHC1Biochemical Activityphysical7535773
GHRReconstituted Complexphysical17500058
BTRCReconstituted Complexphysical17500058