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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SFN (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001836 release of cytochrome c from mitochondria IDA GO:0006469 negative regulation of protein kinase activity TAS GO:0006915 apoptosis IDA GO:0007165 signal transduction TAS GO:0008283 cell proliferation TAS GO:0008630 DNA damage response, signal transduction resulting in induction of apoptosis IDA GO:0030307 positive regulation of cell growth IEA GO:0043154 negative regulation of caspase activity IDA GO:0046827 positive regulation of protein export from nucleus IEA cellular_component GO:0005576 extracellular region IEA GO:0005615 extracellular space TAS GO:0005634 nucleus IEA GO:0005737 cytoplasm IDA molecular_function GO:0005515 protein binding IPI GO:0008426 protein kinase C inhibitor activity TAS GO:0019904 protein domain specific binding IEA GO:0051219 phosphoprotein binding IEA

Protein-protein interaction details for SFN (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID NR3C1 Two-hybrid physical 12730237 BAD Two-hybrid physical 16189514 PLEKHF2 Two-hybrid physical 16189514 PLK4 Two-hybrid physical 16189514 MARK3 Two-hybrid physical 16189514 WDYHV1 Two-hybrid physical 16189514 CHST1 Two-hybrid physical 16189514 TBL3 Two-hybrid physical 16189514 FAM189A2 Two-hybrid physical 16189514 KIAA0408 Two-hybrid physical 16189514 GPRIN2 Two-hybrid physical 16189514 PLK4 Affinity Capture-Western physical 16189514 CHEK1 Affinity Capture-Western physical 11896572 ABLIM1 Affinity Capture-MS physical 15778465 PARD3B Affinity Capture-MS physical 15778465 ANKS1A Affinity Capture-MS physical 15778465 APC Affinity Capture-MS physical 15778465 APLP2 Affinity Capture-MS physical 15778465 ARAF Affinity Capture-MS physical 15778465 SORBS2 Affinity Capture-MS physical 15778465 ARHGAP11A Affinity Capture-MS physical 15778465 ARHGAP21 Affinity Capture-MS physical 15778465 ARHGEF16 Affinity Capture-MS physical 15778465 ARHGEF17 Affinity Capture-MS physical 15778465 ARHGEF5 Affinity Capture-MS physical 15778465 BCAR1 Affinity Capture-MS physical 15778465 BRAF Affinity Capture-MS physical 15778465 CGN Affinity Capture-MS physical 15778465 CSNK2A1 Affinity Capture-MS physical 15778465 DTX2 Affinity Capture-MS physical 15778465 DYRK1A Affinity Capture-MS physical 15778465 ERRFI1 Affinity Capture-MS physical 15778465 ERRFI1 Affinity Capture-Western physical 15778465 SRSF10 Affinity Capture-MS physical 15778465 GAN Affinity Capture-MS physical 15778465 GRB7 Affinity Capture-MS physical 15778465 HDAC4 Affinity Capture-MS physical 15778465 HDAC7 Affinity Capture-MS physical 15778465 HNRNPU Affinity Capture-MS physical 15778465 IRS1 Affinity Capture-MS physical 15778465 IRS2 Affinity Capture-MS physical 15778465 ITCH Affinity Capture-MS physical 15778465 JUB Affinity Capture-MS physical 15778465 JUB Affinity Capture-Western physical 15778465 KIF23 Affinity Capture-MS physical 15778465 KIF5B Affinity Capture-MS physical 15778465 KLC2 Affinity Capture-MS physical 15778465 KLHDC2 Affinity Capture-MS physical 15778465 KLC1 Affinity Capture-MS physical 15778465 LAD1 Affinity Capture-MS physical 15778465 LSR Affinity Capture-MS physical 15778465 LMO7 Affinity Capture-MS physical 15778465 MAGI1 Affinity Capture-MS physical 15778465 MAP3K2 Affinity Capture-MS physical 15778465 MAPKAP1 Affinity Capture-MS physical 15778465 MARK1 Affinity Capture-MS physical 15778465 MARK2 Affinity Capture-MS physical 15778465 MARK3 Affinity Capture-MS physical 15778465 MPRIP Affinity Capture-MS physical 15778465 MYCBP2 Affinity Capture-MS physical 15778465 NEDD4L Affinity Capture-MS physical 15778465 ISCU Affinity Capture-MS physical 15778465 OSBPL3 Affinity Capture-MS physical 15778465 PAK4 Affinity Capture-MS physical 15778465 PARD3 Affinity Capture-MS physical 15778465 PIK3C2B Affinity Capture-MS physical 15778465 PI4KB Affinity Capture-MS physical 15778465 PKP2 Affinity Capture-MS physical 15778465 PKP3 Affinity Capture-MS physical 15778465 PPFIBP1 Affinity Capture-MS physical 15778465 PPFIBP2 Affinity Capture-MS physical 15778465 PPP1R3D Affinity Capture-MS physical 15778465 CYTH2 Affinity Capture-MS physical 15778465 PTOV1 Affinity Capture-MS physical 15778465 PTPN2 Affinity Capture-MS physical 15778465 PTPN3 Affinity Capture-MS physical 15778465 RACGAP1 Affinity Capture-MS physical 15778465 RAE1 Affinity Capture-MS physical 15778465 RAF1 Affinity Capture-MS physical 15778465 RALGPS2 Affinity Capture-MS physical 15778465 RHPN2 Affinity Capture-MS physical 15778465 ARHGAP32 Affinity Capture-MS physical 15778465 RND3 Affinity Capture-MS physical 15778465 SASH1 Affinity Capture-MS physical 15778465 SAV1 Affinity Capture-MS physical 15778465 YWHAG Affinity Capture-MS physical 15778465 SH2D3A Affinity Capture-MS physical 15778465 SH3BP4 Affinity Capture-MS physical 15778465 SHCBP1 Affinity Capture-MS physical 15778465 SHROOM3 Affinity Capture-MS physical 15778465 SIPA1L1 Affinity Capture-MS physical 15778465 SIPA1L3 Affinity Capture-MS physical 15778465 SPIRE1 Affinity Capture-MS physical 15778465 SRRM2 Affinity Capture-MS physical 15778465 ST5 Affinity Capture-MS physical 15778465 SYNJ2 Affinity Capture-MS physical 15778465 TJP2 Affinity Capture-MS physical 15778465 TNK1 Affinity Capture-MS physical 15778465 TNS4 Affinity Capture-MS physical 15778465 TRIM32 Affinity Capture-MS physical 15778465 USP8 Affinity Capture-MS physical 15778465 DCAF7 Affinity Capture-MS physical 15778465 WEE1 Affinity Capture-MS physical 15778465 YWHAG Affinity Capture-MS physical 15778465 ZAK Affinity Capture-MS physical 15778465 ZNF638 Affinity Capture-MS physical 15778465 TP53 Affinity Capture-Western physical 11896572 CDK1 Affinity Capture-Western physical 10524633 TRIM25 Affinity Capture-Western physical 12075357 UBC Affinity Capture-Western physical 18382127 MDM2 Affinity Capture-Western physical 17546054 MDM2 Affinity Capture-Western physical 17546054 MDM2 Reconstituted Complex physical 17546054 TP53 Affinity Capture-Western physical 17546054 MDM4 Affinity Capture-Western physical 16511560 ING1 Reconstituted Complex physical 16581770 TP53 Affinity Capture-Western physical 14517281 TP53 Reconstituted Complex physical 14517281 HDAC9 Affinity Capture-Western physical 15166223 SAMSN1 Reconstituted Complex physical 20478393 YWHAQ Affinity Capture-MS physical 20618440 UBC Affinity Capture-Western physical 22178446 UBC Affinity Capture-MS physical 21987572 EXO1 Two-hybrid physical 22222486 EXO1 Reconstituted Complex physical 22222486