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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for FOXA2 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000432positive regulation of transcription from RNA polymerase II promoter by glucoseISS
GO:0000433negative regulation of transcription from RNA polymerase II promoter by glucoseISS
GO:0001701in utero embryonic developmentIBA
GO:0001705ectoderm formationIBA
GO:0006351transcription, DNA-dependentIDA
GO:0006357regulation of transcription from RNA polymerase II promoterIDA
GO:0007389pattern specification processIEA
GO:0007492endoderm developmentIBA
GO:0009952anterior/posterior pattern specificationIBA
GO:0010719negative regulation of epithelial to mesenchymal transitionIMP
GO:0016568chromatin modificationIEA
GO:0021533cell differentiation in hindbrainIBA
GO:0021779oligodendrocyte cell fate commitmentIBA
GO:0021904dorsal/ventral neural tube patterningIBA
GO:0023019signal transduction involved in regulation of gene expressionIEA
GO:0030193regulation of blood coagulationIDA
GO:0030324lung developmentIEA
GO:0031018endocrine pancreas developmentIBA
GO:0031018endocrine pancreas developmentIDA
GO:0032289central nervous system myelin formationIBA
GO:0032525somite rostral/caudal axis specificationIEA
GO:0032868response to insulin stimulusIEA
GO:0033132negative regulation of glucokinase activityISS
GO:0040019positive regulation of embryonic developmentISS
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activityIMP
GO:0045665negative regulation of neuron differentiationIBA
GO:0045666positive regulation of neuron differentiationIBA
GO:0045893positive regulation of transcription, DNA-dependentIDA
GO:0045893positive regulation of transcription, DNA-dependentISS
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0045945positive regulation of transcription from RNA polymerase III promoterIEA
GO:0048468cell developmentIEA
GO:0048665neuron fate specificationIBA
GO:0051090regulation of sequence-specific DNA binding transcription factor activityIBA
GO:0060441epithelial tube branching involved in lung morphogenesisIBA
GO:0060487lung epithelial cell differentiationIBA
GO:0061178regulation of insulin secretion involved in cellular response to glucose stimulusISS
GO:0070741response to interleukin-6TAS
GO:0090009primitive streak formationISS
GO:2000049positive regulation of cell-cell adhesion mediated by cadherinIC
GO:2000543positive regulation of gastrulationISS
GO:2000971negative regulation of detection of glucoseISS
GO:2000976regulation of transcription from RNA polymerase II promoter involved in detection of glucoseISS
cellular_component
GO:0005634nucleusIDA
GO:0005667transcription factor complexIBA
GO:0005737cytoplasmIEA
GO:0044464cell partIEA
molecular_function
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA bindingIDA
GO:0003677DNA bindingIDA
GO:0003690double-stranded DNA bindingIBA
GO:0003700sequence-specific DNA binding transcription factor activityIDA
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0003705sequence-specific distal enhancer binding RNA polymerase II transcription factor activityIBA
GO:0008134transcription factor bindingIBA
GO:0008134transcription factor bindingIEA
GO:0008301DNA bending activityIBA
GO:0019904protein domain specific bindingIBA
GO:0019904protein domain specific bindingIEA
GO:0043565sequence-specific DNA bindingIEA
GO:0044212transcription regulatory region DNA bindingIMP
GO:0046332SMAD bindingIEA

Protein-protein interaction details for FOXA2 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
TLE1Two-hybridphysical10748198
EN2Reconstituted Complexphysical12642491
HOXA5Reconstituted Complexphysical12642491
LHX1Reconstituted Complexphysical12642491
GSCReconstituted Complexphysical12642491
OTX2Reconstituted Complexphysical12642491
NCOA1Two-hybridphysical11069927
ONECUT1Reconstituted Complexphysical12509444
ONECUT1Affinity Capture-Westernphysical12509444
OTX2Reconstituted Complexphysical10623575
TLE1Reconstituted Complexphysical10748198
HOXA5Reconstituted Complexphysical12163409
PPARGC1BAffinity Capture-Westernphysical16459311