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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for HSPA1A (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006402 mRNA catabolic process IDA GO:0006916 anti-apoptosis TAS GO:0006950 response to stress IEA GO:0006986 response to unfolded protein IDA GO:0008285 negative regulation of cell proliferation IMP GO:0016070 RNA metabolic process TAS GO:0016071 mRNA metabolic process TAS GO:0030308 negative regulation of cell growth IMP GO:0042026 protein refolding IDA GO:0090084 negative regulation of inclusion body assembly IDA cellular_component GO:0005634 nucleus IDA GO:0005737 cytoplasm IDA GO:0005737 cytoplasm TAS GO:0005739 mitochondrion TAS GO:0005783 endoplasmic reticulum TAS GO:0005829 cytosol TAS GO:0008180 signalosome IDA GO:0016234 inclusion body IDA GO:0016607 nuclear speck IDA GO:0030529 ribonucleoprotein complex IDA GO:0048471 perinuclear region of cytoplasm IDA molecular_function GO:0000166 nucleotide binding IEA GO:0004872 receptor activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0031625 ubiquitin protein ligase binding IPI GO:0044183 protein binding involved in protein folding IDA GO:0047485 protein N-terminus binding IPI GO:0051082 unfolded protein binding TAS

Protein-protein interaction details for HSPA1A (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID FANCC Affinity Capture-Western physical 12397061 AR Affinity Capture-Western physical 1540595 BAG1 Reconstituted Complex physical 14517289 FANCC Two-hybrid physical 14499622 AIFM1 Affinity Capture-Western physical 12930708 IKBKG Reconstituted Complex physical 11877453 MSR1 Affinity Capture-Western physical 11785981 MSR1 Reconstituted Complex physical 11785981 RHOA Affinity Capture-Western physical 12490434 HSF1 Affinity Capture-Western physical 9499401 HSF1 Affinity Capture-Western physical 9499401 HSF1 Reconstituted Complex physical 9499401 NR3C1 Reconstituted Complex physical 12093808 HSP90AA1 Reconstituted Complex physical 12093808 RBX1 Affinity Capture-MS physical 12481031 CUL4A Affinity Capture-MS physical 12481031 SLC5A1 Affinity Capture-Western physical 12082088 MAP3K5 Reconstituted Complex physical 12391142 MAP3K5 Affinity Capture-Western physical 12391142 BCL2 Affinity Capture-Western physical 10354271 HSF1 Affinity Capture-Western physical 9699716 AIFM1 Affinity Capture-Western physical 11533664 STUB1 Reconstituted Complex physical 10330192 STUB1 Affinity Capture-Western physical 10330192 BAT3 Affinity Capture-Western physical 11230127 BAG3 Affinity Capture-Western physical 10980614 SOX9 Affinity Capture-Western physical 11356186 BAG3 Affinity Capture-Western physical 11527400 CDK9 Affinity Capture-Western physical 10617616 ST13 Reconstituted Complex physical 8887650 PARK2 Affinity Capture-MS physical 12150907 PARK2 Affinity Capture-Western physical 12150907 GPR37 Affinity Capture-Western physical 12150907 STUB1 Reconstituted Complex physical 12150907 GPR37 Reconstituted Complex physical 12150907 PARK2 Reconstituted Complex physical 12150907 PACSIN1 Affinity Capture-MS physical 19041431 PACSIN2 Affinity Capture-MS physical 19041431 PACSIN3 Affinity Capture-MS physical 19041431 FNBP1 Affinity Capture-MS physical 19041431 PSTPIP1 Affinity Capture-MS physical 19041431 FCHSD1 Affinity Capture-MS physical 19041431 EGFR PCA physical 20029029 SNCA FRET physical 19875982 SNCB FRET physical 19875982 SNCA Reconstituted Complex physical 19875982 RAPGEF2 Two-hybrid physical 20936779 MYSM1 Affinity Capture-MS physical 17707232 SUMO2 Affinity Capture-MS physical 19394292 SRRM2 Affinity Capture-MS physical 16159877 KDM1A Affinity Capture-MS physical 16140033 MAX Affinity Capture-MS physical 20946988 HSF1 Affinity Capture-Western physical 21784850 H2AFX Affinity Capture-MS physical 20000738 UBC Affinity Capture-MS physical 16196087 USP50 Affinity Capture-MS physical 20930503 EIF2C4 Affinity Capture-MS physical 19167051 MME Affinity Capture-MS physical 17342744 HDAC5 Affinity Capture-MS physical 21081666 DYRK2 Affinity Capture-MS physical 19287380 YWHAG Affinity Capture-MS physical 15324660 STK11 Affinity Capture-MS physical 14676191 INSIG2 Affinity Capture-MS physical 19815544 SUMO1 Affinity Capture-MS physical 19596686 TP53 Affinity Capture-Western physical 8729618 UBC Affinity Capture-MS physical 20639865 BAP1 Co-purification physical 20805357