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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IFIT1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0009615response to virusIDA
GO:0009615response to virusIEA
GO:0019060intracellular transport of viral proteins in host cellIDA
GO:0019221cytokine-mediated signaling pathwayTAS
GO:0032091negative regulation of protein bindingIDA
GO:0045070positive regulation of viral genome replicationIDA
GO:0045071negative regulation of viral genome replicationIMP
GO:0050688regulation of defense response to virusIEA
GO:0050689negative regulation of defense response to virus by hostIDA
GO:0051097negative regulation of helicase activityIDA
GO:0060337type I interferon-mediated signaling pathwayTAS
GO:0071357cellular response to type I interferonIDA
GO:0071357cellular response to type I interferonIEA
GO:0071360cellular response to exogenous dsRNAIDA
GO:0071360cellular response to exogenous dsRNAIEA
cellular_component
GO:0005737cytoplasmIDA
GO:0005829cytosolTAS
molecular_function
GO:0005488bindingIEA
GO:0005515protein bindingIPI

Protein-protein interaction details for IFIT1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
IFIT3Two-hybridphysical16189514
EIF3EAffinity Capture-Westernphysical10644362
SAP25Affinity Capture-MSphysical16449650