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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IFNB1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002250adaptive immune responseIEA
GO:0006917induction of apoptosisIDA
GO:0006919activation of caspase activityIDA
GO:0006919activation of caspase activityNAS
GO:0006959humoral immune responseIEA
GO:0007166cell surface receptor linked signaling pathwayTAS
GO:0007596blood coagulationTAS
GO:0008285negative regulation of cell proliferationNAS
GO:0009615response to virusNAS
GO:0019221cytokine-mediated signaling pathwayTAS
GO:0030101natural killer cell activationNAS
GO:0032897negative regulation of viral transcriptionIDA
GO:0042100B cell proliferationNAS
GO:0042742defense response to bacteriumIEA
GO:0045071negative regulation of viral genome replicationIDA
GO:0045087innate immune responseTAS
GO:0045089positive regulation of innate immune responseNAS
GO:0045343regulation of MHC class I biosynthetic processNAS
GO:0045581negative regulation of T cell differentiationIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0046597negative regulation of virion penetration into host cellNAS
GO:0051607defense response to virusIDA
GO:0060337type I interferon-mediated signaling pathwayTAS
GO:0060338regulation of type I interferon-mediated signaling pathwayTAS
GO:0071360cellular response to exogenous dsRNAIMP
GO:2000552negative regulation of T-helper 2 cell cytokine productionIDA
cellular_component
GO:0005576extracellular regionIC
GO:0005576extracellular regionTAS
GO:0005615extracellular spaceIEA
molecular_function
GO:0003714transcription corepressor activityIDA
GO:0005125cytokine activityIEA
GO:0005132interferon-alpha/beta receptor bindingNAS

Protein-protein interaction details for IFNB1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
IFNB1Co-crystal Structurephysical9342320