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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IGFBP5 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001558regulation of cell growthIEA
GO:0001649osteoblast differentiationIEA
GO:0006006glucose metabolic processIEA
GO:0007165signal transductionNAS
GO:0014912negative regulation of smooth muscle cell migrationIDA
GO:0017148negative regulation of translationIDA
GO:0030336negative regulation of cell migrationIDA
GO:0031069hair follicle morphogenesisIEA
GO:0035556intracellular signal transductionIEA
GO:0042593glucose homeostasisIEA
GO:0043569negative regulation of insulin-like growth factor receptor signaling pathwayIDA
GO:0048630skeletal muscle tissue growthIEA
GO:0048662negative regulation of smooth muscle cell proliferationIDA
GO:0051146striated muscle cell differentiationIEA
GO:0051897positive regulation of protein kinase B signaling cascadeIEA
GO:0060056mammary gland involutionIEA
GO:0071320cellular response to cAMPIDA
GO:0071407cellular response to organic cyclic compoundIDA
cellular_component
GO:0005576extracellular regionIEA
GO:0005576extracellular regionNAS
GO:0005576extracellular regionTAS
GO:0016942insulin-like growth factor binding protein complexIC
molecular_function
GO:0001968fibronectin bindingIEA
GO:0005515protein bindingIPI
GO:0005520insulin-like growth factor bindingIEA
GO:0031994insulin-like growth factor I bindingIPI

Protein-protein interaction details for IGFBP5 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
BAT3Two-hybridphysical16169070
THBS1Reconstituted Complexphysical10698186
SPP1Reconstituted Complexphysical10698186
ADAM12Biochemical Activityphysical11095942
FHL2Two-hybridphysical11821401
FHL2Reconstituted Complexphysical11821401
FHL2Affinity Capture-Westernphysical11821401
SERPINE1Affinity Capture-Westernphysical9202242
VTNReconstituted Complexphysical11751588
IGFALSReconstituted Complexphysical9497324
IGF1Reconstituted Complexphysical9497324
IGF2Reconstituted Complexphysical9497324