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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IL12A (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001916positive regulation of T cell mediated cytotoxicityIDA
GO:0002860positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell targetIDA
GO:0006955immune responseIEA
GO:0006955immune responseTAS
GO:0007050cell cycle arrestIDA
GO:0009615response to virusIEP
GO:0010224response to UV-BIDA
GO:0016477cell migrationIDA
GO:0032496response to lipopolysaccharideIDA
GO:0032700negative regulation of interleukin-17 productionIDA
GO:0032729positive regulation of interferon-gamma productionIDA
GO:0032816positive regulation of natural killer cell activationIDA
GO:0034393positive regulation of smooth muscle cell apoptosisIDA
GO:0042102positive regulation of T cell proliferationIEA
GO:0042520positive regulation of tyrosine phosphorylation of Stat4 proteinIDA
GO:0042832defense response to protozoanIEA
GO:0045785positive regulation of cell adhesionIDA
GO:0045954positive regulation of natural killer cell mediated cytotoxicityIDA
GO:0048662negative regulation of smooth muscle cell proliferationIDA
GO:0050671positive regulation of lymphocyte proliferationIDA
GO:0050830defense response to Gram-positive bacteriumIEP
GO:0051135positive regulation of NK T cell activationIDA
cellular_component
GO:0005576extracellular regionIEA
GO:0005615extracellular spaceIDA
GO:0005737cytoplasmIEA
GO:0043514interleukin-12 complexIDA
GO:0043514interleukin-12 complexNAS
molecular_function
GO:0005125cytokine activityIDA
GO:0005125cytokine activityTAS
GO:0005143interleukin-12 receptor bindingIEA
GO:0005143interleukin-12 receptor bindingNAS
GO:0005515protein bindingIPI
GO:0008083growth factor activityIDA
GO:0008083growth factor activityIEA
GO:0008083growth factor activityNAS
GO:0042163interleukin-12 beta subunit bindingIEA
GO:0045513interleukin-27 bindingIPI
GO:0046982protein heterodimerization activityIPI

Protein-protein interaction details for IL12A (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
IL12BCo-crystal Structurephysical10899108