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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for LIF (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001974blood vessel remodelingIEA
GO:0006955immune responseIEA
GO:0007275multicellular organismal developmentTAS
GO:0007566embryo implantationIEA
GO:0008284positive regulation of cell proliferationIDA
GO:0008285negative regulation of cell proliferationIEA
GO:0010976positive regulation of neuron projection developmentIEA
GO:0016525negative regulation of angiogenesisIEA
GO:0019827stem cell maintenanceIEA
GO:0031100organ regenerationIEA
GO:0033138positive regulation of peptidyl-serine phosphorylationIDA
GO:0033141positive regulation of peptidyl-serine phosphorylation of STAT proteinIDA
GO:0042511positive regulation of tyrosine phosphorylation of Stat1 proteinIDA
GO:0042517positive regulation of tyrosine phosphorylation of Stat3 proteinIDA
GO:0043410positive regulation of MAPKKK cascadeIDA
GO:0045595regulation of cell differentiationIEA
GO:0045651positive regulation of macrophage differentiationIDA
GO:0045835negative regulation of meiosisIEA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0046697decidualizationIEA
GO:0046888negative regulation of hormone secretionIDA
GO:0048286lung alveolus developmentIEA
GO:0048644muscle organ morphogenesisIEA
GO:0048666neuron developmentIEA
GO:0048711positive regulation of astrocyte differentiationIEA
GO:0048861leukemia inhibitory factor signaling pathwayIDA
GO:0050731positive regulation of peptidyl-tyrosine phosphorylationIDA
GO:0051461positive regulation of corticotropin secretionIEA
GO:0060041retina development in camera-type eyeIEA
GO:0060135maternal process involved in female pregnancyIEA
GO:0060290transdifferentiationIEA
GO:0060426lung vasculature developmentIEA
GO:0060463lung lobe morphogenesisIEA
GO:0060707trophoblast giant cell differentiationIEA
GO:0060708spongiotrophoblast differentiationIEA
GO:0070373negative regulation of ERK1 and ERK2 cascadeIEA
GO:0072108positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesisIDA
GO:0072307regulation of metanephric nephron tubule epithelial cell differentiationIDA
cellular_component
GO:0005576extracellular regionIEA
GO:0005615extracellular spaceIC
molecular_function
GO:0005102receptor bindingIPI
GO:0005125cytokine activityIDA
GO:0005146leukemia inhibitory factor receptor bindingIDA
GO:0005146leukemia inhibitory factor receptor bindingIPI
GO:0008083growth factor activityIDA

Protein-protein interaction details for LIF (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
LIFRReconstituted Complexphysical12601009