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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for MC1R (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0007187
G-protein signaling, coupled to cyclic nucleotide second messenger
TAS
GO:0007243
intracellular protein kinase cascade
ISS
GO:0007275
multicellular organismal development
TAS
GO:0009650
UV protection
TAS
GO:0010739
positive regulation of protein kinase A signaling cascade
ISS
GO:0030819
positive regulation of cAMP biosynthetic process
IDA
GO:0032720
negative regulation of tumor necrosis factor production
IMP
GO:0043473
pigmentation
TAS
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
ISS
GO:0051897
positive regulation of protein kinase B signaling cascade
ISS
GO:0070914
UV-damage excision repair
IDA
GO:0090037
positive regulation of protein kinase C signaling cascade
ISS
cellular_component
GO:0005886
plasma membrane
IDA
GO:0005886
plasma membrane
TAS
GO:0005887
integral to plasma membrane
TAS
molecular_function
GO:0004871
signal transducer activity
IEA
GO:0004872
receptor activity
IEA
GO:0004977
melanocortin receptor activity
TAS
GO:0004980
melanocyte-stimulating hormone receptor activity
IPI
GO:0005515
protein binding
IPI
GO:0008528
peptide receptor activity, G-protein coupled
TAS
GO:0031625
ubiquitin protein ligase binding
IPI
Protein-protein interaction details for MC1R (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
POMC
Reconstituted Complex
physical
9058374
MGRN1
Affinity Capture-Western
physical
19737927
MGRN1
Affinity Capture-Western
physical
19737927
MGRN1
Affinity Capture-Western
physical
21862608