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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MC1R (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0007187G-protein signaling, coupled to cyclic nucleotide second messengerTAS
GO:0007243intracellular protein kinase cascadeISS
GO:0007275multicellular organismal developmentTAS
GO:0009650UV protectionTAS
GO:0010739positive regulation of protein kinase A signaling cascadeISS
GO:0030819positive regulation of cAMP biosynthetic processIDA
GO:0032720negative regulation of tumor necrosis factor productionIMP
GO:0043473pigmentationTAS
GO:0045944positive regulation of transcription from RNA polymerase II promoterISS
GO:0051897positive regulation of protein kinase B signaling cascadeISS
GO:0070914UV-damage excision repairIDA
GO:0090037positive regulation of protein kinase C signaling cascadeISS
cellular_component
GO:0005886plasma membraneIDA
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneTAS
molecular_function
GO:0004871signal transducer activityIEA
GO:0004872receptor activityIEA
GO:0004977melanocortin receptor activityTAS
GO:0004980melanocyte-stimulating hormone receptor activityIPI
GO:0005515protein bindingIPI
GO:0008528peptide receptor activity, G-protein coupledTAS
GO:0031625ubiquitin protein ligase bindingIPI

Protein-protein interaction details for MC1R (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
POMCReconstituted Complexphysical9058374
MGRN1Affinity Capture-Westernphysical19737927
MGRN1Affinity Capture-Westernphysical19737927
MGRN1Affinity Capture-Westernphysical21862608