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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MITF (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006355 regulation of transcription, DNA-dependent IEA GO:0006355 regulation of transcription, DNA-dependent NAS GO:0006461 protein complex assembly IDA GO:0007275 multicellular organismal development IEA GO:0016055 Wnt receptor signaling pathway IEA GO:0030318 melanocyte differentiation IEA GO:0030318 melanocyte differentiation NAS GO:0042127 regulation of cell proliferation IEA GO:0043010 camera-type eye development IEA GO:0043066 negative regulation of apoptosis IEA GO:0043473 pigmentation IEA GO:0045165 cell fate commitment IEA GO:0045670 regulation of osteoclast differentiation IEA GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045893 positive regulation of transcription, DNA-dependent NAS GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0046849 bone remodeling IEA cellular_component GO:0005634 nucleus IEA GO:0005634 nucleus NAS GO:0043234 protein complex IDA molecular_function GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IDA GO:0003677 DNA binding IEA GO:0003682 chromatin binding IEA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0003705 sequence-specific distal enhancer binding RNA polymerase II transcription factor activity IEA GO:0005515 protein binding IPI

Protein-protein interaction details for MITF (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID LEF1 Two-hybrid physical 12032083 PIAS3 Two-hybrid physical 11709556 PATZ1 Two-hybrid physical 11751862 UBE2I Two-hybrid physical 10694430 TFE3 Phenotypic Enhancement genetic 11930005 PIAS3 Reconstituted Complex physical 11709556 PIAS3 Affinity Capture-Western physical 11709556 PIAS3 Affinity Capture-Western physical 11709556 FOS Affinity Capture-Western physical 9918847 SPI1 Reconstituted Complex physical 9918847 PAX6 Reconstituted Complex physical 11350962 TFE3 Affinity Capture-Western physical 11818452 TFEC Affinity Capture-Western physical 11818452 PATZ1 Affinity Capture-Western physical 11751862 PATZ1 Reconstituted Complex physical 11751862 UBE2I Reconstituted Complex physical 10694430 LEF1 Affinity Capture-Western physical 12032083 LEF1 Reconstituted Complex physical 12032083 SUMO1 Affinity Capture-Western physical 16029420 SUMO1 Affinity Capture-Western physical 16029420 UBE2I Reconstituted Complex physical 16029420 PIAS1 Reconstituted Complex physical 16029420 PIAS3 Reconstituted Complex physical 16029420 PIAS2 Reconstituted Complex physical 16029420 PIAS2 Reconstituted Complex physical 16029420 PSMD14 Two-hybrid physical 20058232 MARK3 Two-hybrid physical 20058232 PSMD14 Affinity Capture-Western physical 20058232