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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NGF (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000186activation of MAPKK activityTAS
GO:0006915apoptosisTAS
GO:0006916anti-apoptosisTAS
GO:0006954inflammatory responseIEA
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathwayTAS
GO:0007202activation of phospholipase C activityTAS
GO:0007264small GTPase mediated signal transductionTAS
GO:0007265Ras protein signal transductionTAS
GO:0007422peripheral nervous system developmentIEA
GO:0007613memoryIEA
GO:0008284positive regulation of cell proliferationIEA
GO:0008344adult locomotory behaviorIEA
GO:0008624induction of apoptosis by extracellular signalsTAS
GO:0009314response to radiationIEA
GO:0009612response to mechanical stimulusIEA
GO:0019233sensory perception of painIEA
GO:0031175neuron projection developmentIEA
GO:0031954positive regulation of protein autophosphorylationIEA
GO:0032455nerve growth factor processingTAS
GO:0032496response to lipopolysaccharideIEA
GO:0035094response to nicotineIEA
GO:0042493response to drugIEA
GO:0043434response to peptide hormone stimulusIEA
GO:0043524negative regulation of neuron apoptosisIEA
GO:0045664regulation of neuron differentiationIEA
GO:0045773positive regulation of axon extensionIEA
GO:0045786negative regulation of cell cycleTAS
GO:0046928regulation of neurotransmitter secretionIEA
GO:0048011nerve growth factor receptor signaling pathwayTAS
GO:0048015phosphatidylinositol-mediated signalingTAS
GO:0050770regulation of axonogenesisTAS
GO:0050772positive regulation of axonogenesisTAS
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activityIEA
GO:0051384response to glucocorticoid stimulusIEA
GO:0051388positive regulation of nerve growth factor receptor signaling pathwayIEA
GO:0051602response to electrical stimulusIEA
cellular_component
GO:0005576extracellular regionTAS
GO:0005615extracellular spaceIEA
GO:0005768endosomeTAS
GO:0005788endoplasmic reticulum lumenIEA
GO:0005796Golgi lumenTAS
molecular_function
GO:0004871signal transducer activityTAS
GO:0005057receptor signaling protein activityIEA
GO:0005163nerve growth factor receptor bindingIPI
GO:0008083growth factor activityIEA

Protein-protein interaction details for NGF (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
SORT1Reconstituted Complexphysical14985763
NGFRReconstituted Complexphysical14985763
NTRK1Reconstituted Complexphysical14985763
NTRK1Reconstituted Complexphysical11729324
NGFRReconstituted Complexphysical11729324
A2MReconstituted Complexphysical10681572
NTRK1Co-crystal Structurephysical10490030