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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for NGF (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000186
activation of MAPKK activity
TAS
GO:0006915
apoptosis
TAS
GO:0006916
anti-apoptosis
TAS
GO:0006954
inflammatory response
IEA
GO:0007169
transmembrane receptor protein tyrosine kinase signaling pathway
TAS
GO:0007202
activation of phospholipase C activity
TAS
GO:0007264
small GTPase mediated signal transduction
TAS
GO:0007265
Ras protein signal transduction
TAS
GO:0007422
peripheral nervous system development
IEA
GO:0007613
memory
IEA
GO:0008284
positive regulation of cell proliferation
IEA
GO:0008344
adult locomotory behavior
IEA
GO:0008624
induction of apoptosis by extracellular signals
TAS
GO:0009314
response to radiation
IEA
GO:0009612
response to mechanical stimulus
IEA
GO:0019233
sensory perception of pain
IEA
GO:0031175
neuron projection development
IEA
GO:0031954
positive regulation of protein autophosphorylation
IEA
GO:0032455
nerve growth factor processing
TAS
GO:0032496
response to lipopolysaccharide
IEA
GO:0035094
response to nicotine
IEA
GO:0042493
response to drug
IEA
GO:0043434
response to peptide hormone stimulus
IEA
GO:0043524
negative regulation of neuron apoptosis
IEA
GO:0045664
regulation of neuron differentiation
IEA
GO:0045773
positive regulation of axon extension
IEA
GO:0045786
negative regulation of cell cycle
TAS
GO:0046928
regulation of neurotransmitter secretion
IEA
GO:0048011
nerve growth factor receptor signaling pathway
TAS
GO:0048015
phosphatidylinositol-mediated signaling
TAS
GO:0050770
regulation of axonogenesis
TAS
GO:0050772
positive regulation of axonogenesis
TAS
GO:0051091
positive regulation of sequence-specific DNA binding transcription factor activity
IEA
GO:0051384
response to glucocorticoid stimulus
IEA
GO:0051388
positive regulation of nerve growth factor receptor signaling pathway
IEA
GO:0051602
response to electrical stimulus
IEA
cellular_component
GO:0005576
extracellular region
TAS
GO:0005615
extracellular space
IEA
GO:0005768
endosome
TAS
GO:0005788
endoplasmic reticulum lumen
IEA
GO:0005796
Golgi lumen
TAS
molecular_function
GO:0004871
signal transducer activity
TAS
GO:0005057
receptor signaling protein activity
IEA
GO:0005163
nerve growth factor receptor binding
IPI
GO:0008083
growth factor activity
IEA
Protein-protein interaction details for NGF (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
SORT1
Reconstituted Complex
physical
14985763
NGFR
Reconstituted Complex
physical
14985763
NTRK1
Reconstituted Complex
physical
14985763
NTRK1
Reconstituted Complex
physical
11729324
NGFR
Reconstituted Complex
physical
11729324
A2M
Reconstituted Complex
physical
10681572
NTRK1
Co-crystal Structure
physical
10490030