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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NOS1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001666 response to hypoxia IEP GO:0002028 regulation of sodium ion transport IEA GO:0006527 arginine catabolic process IC GO:0006809 nitric oxide biosynthetic process IEA GO:0006809 nitric oxide biosynthetic process ISS GO:0006941 striated muscle contraction IEA GO:0007520 myoblast fusion TAS GO:0007596 blood coagulation TAS GO:0009408 response to heat IDA GO:0010523 negative regulation of calcium ion transport into cytosol TAS GO:0018119 peptidyl-cysteine S-nitrosylation IEA GO:0030168 platelet activation TAS GO:0033555 multicellular organismal response to stress IMP GO:0035066 positive regulation of histone acetylation IEA GO:0042136 neurotransmitter biosynthetic process TAS GO:0042738 exogenous drug catabolic process IEA GO:0043267 negative regulation of potassium ion transport IEA GO:0045893 positive regulation of transcription, DNA-dependent IEA GO:0045909 positive regulation of vasodilation IDA GO:0045909 positive regulation of vasodilation IMP GO:0051346 negative regulation of hydrolase activity IEA GO:0051612 negative regulation of serotonin uptake IEA GO:0055117 regulation of cardiac muscle contraction TAS GO:0071363 cellular response to growth factor stimulus IEA cellular_component GO:0001917 photoreceptor inner segment ISS GO:0005737 cytoplasm TAS GO:0005829 cytosol TAS GO:0005856 cytoskeleton ISS GO:0016529 sarcoplasmic reticulum IDA GO:0042383 sarcolemma IDA GO:0042995 cell projection IEA GO:0043197 dendritic spine IEA GO:0045202 synapse IEA GO:0048471 perinuclear region of cytoplasm ISS molecular_function GO:0004517 nitric-oxide synthase activity IEA GO:0004517 nitric-oxide synthase activity ISS GO:0005515 protein binding IPI GO:0005516 calmodulin binding IEA GO:0010181 FMN binding IEA GO:0010181 FMN binding ISS GO:0016491 oxidoreductase activity IEA GO:0020037 heme binding IEA GO:0020037 heme binding ISS GO:0034617 tetrahydrobiopterin binding NAS GO:0034618 arginine binding TAS GO:0046870 cadmium ion binding ISS GO:0046872 metal ion binding IEA GO:0050660 flavin adenine dinucleotide binding IEA GO:0050660 flavin adenine dinucleotide binding ISS GO:0050661 NADP binding IEA GO:0050661 NADP binding ISS

Protein-protein interaction details for NOS1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ZDHHC23 Affinity Capture-Western physical 15105416 ZDHHC23 Reconstituted Complex physical 15105416 RASD1 Reconstituted Complex physical 11086993 BDKRB2 Affinity Capture-Western physical 10681501 PTPN6 Affinity Capture-Western physical 11511520 SYN1 Reconstituted Complex physical 11867766 SNTA1 Reconstituted Complex physical 9412493 NOS1AP Two-hybrid physical 9459447 NOS1AP Reconstituted Complex physical 9459447 NOS1AP Reconstituted Complex physical 9459447 DLG4 Affinity Capture-Western physical 9459447 NOS1AP Affinity Capture-Western physical 9459447 DLG4 Two-hybrid physical 8625413 DLG2 Two-hybrid physical 8625413 DLG4 Reconstituted Complex physical 8625413 DLG4 Co-purification physical 8625413 UBC Affinity Capture-Western physical 15466472 STUB1 Biochemical Activity physical 15466472 STUB1 Affinity Capture-Western physical 15466472 HSPA4 Affinity Capture-Western physical 15466472 UBC Affinity Capture-Western physical 10751385 SUMO1 Affinity Capture-Western physical 21545853 SUMO1 Reconstituted Complex physical 21545853 UBC Reconstituted Complex physical 18784277 UBC Reconstituted Complex physical 19642705 UBC Reconstituted Complex physical 20729196 STUB1 Biochemical Activity physical 20729196