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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for PLCE1 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000187
activation of MAPK activity
IDA
GO:0001558
regulation of cell growth
TAS
GO:0006644
phospholipid metabolic process
IC
GO:0006651
diacylglycerol biosynthetic process
TAS
GO:0006940
regulation of smooth muscle contraction
TAS
GO:0007010
cytoskeleton organization
NAS
GO:0007173
epidermal growth factor receptor signaling pathway
NAS
GO:0007200
activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
IDA
GO:0007204
elevation of cytosolic calcium ion concentration
TAS
GO:0007205
activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway
NAS
GO:0007265
Ras protein signal transduction
TAS
GO:0007507
heart development
TAS
GO:0008277
regulation of G-protein coupled receptor protein signaling pathway
IDA
GO:0008283
cell proliferation
NAS
GO:0016042
lipid catabolic process
IEA
GO:0019722
calcium-mediated signaling
NAS
GO:0019722
calcium-mediated signaling
TAS
GO:0032835
glomerulus development
IMP
GO:0045859
regulation of protein kinase activity
IDA
GO:0046578
regulation of Ras protein signal transduction
IDA
GO:0048016
inositol phosphate-mediated signaling
TAS
cellular_component
GO:0000139
Golgi membrane
IEA
GO:0005624
membrane fraction
IDA
GO:0005737
cytoplasm
IDA
GO:0005794
Golgi apparatus
IEA
GO:0005829
cytosol
IDA
GO:0005886
plasma membrane
IDA
molecular_function
GO:0004435
phosphatidylinositol phospholipase C activity
IDA
GO:0004629
phospholipase C activity
IDA
GO:0005057
receptor signaling protein activity
TAS
GO:0005085
guanyl-nucleotide exchange factor activity
TAS
GO:0005509
calcium ion binding
IEA
GO:0005515
protein binding
IPI
GO:0016787
hydrolase activity
IEA
GO:0017016
Ras GTPase binding
TAS
GO:0019899
enzyme binding
IPI
Protein-protein interaction details for PLCE1 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
NRAS
Two-hybrid
physical
16169070
SIAH1
Affinity Capture-Western
physical
17998205
SIAH2
Affinity Capture-Western
physical
17998205
SIAH2
Reconstituted Complex
physical
17998205
SIAH2
Affinity Capture-Western
physical
17998205
UBC
Affinity Capture-Western
physical
17998205