Database of mammalian genes
Home

Home Search Browse RAGs User guide FAQs Links Questions Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TLR7 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002282microglial cell activation involved in immune responseIEA
GO:0007165signal transductionIEA
GO:0007252I-kappaB phosphorylationIDA
GO:0032722positive regulation of chemokine productionIDA
GO:0032755positive regulation of interleukin-6 productionIEA
GO:0032757positive regulation of interleukin-8 productionIDA
GO:0034154toll-like receptor 7 signaling pathwayIEA
GO:0042221response to chemical stimulusIEA
GO:0042346positive regulation of NF-kappaB import into nucleusIDA
GO:0045078positive regulation of interferon-gamma biosynthetic processIDA
GO:0045087innate immune responseTAS
GO:0045356positive regulation of interferon-alpha biosynthetic processIDA
GO:0045359positive regulation of interferon-beta biosynthetic processIDA
GO:0045416positive regulation of interleukin-8 biosynthetic processIMP
GO:0050729positive regulation of inflammatory responseIC
GO:0051607defense response to virusIMP
GO:0052033pathogen-associated molecular pattern dependent induction by symbiont of host innate immunityIEA
GO:0071260cellular response to mechanical stimulusIEP
cellular_component
GO:0005737cytoplasmIDA
GO:0005764lysosomeISS
GO:0005768endosomeISS
GO:0005783endoplasmic reticulumISS
GO:0005789endoplasmic reticulum membraneIEA
GO:0005886plasma membraneIDA
GO:0010008endosome membraneTAS
GO:0016021integral to membraneIEA
GO:0031410cytoplasmic vesicleIEA
GO:0032009early phagosomeISS
molecular_function
GO:0003725double-stranded RNA bindingIDA
GO:0003727single-stranded RNA bindingISS
GO:0004872receptor activityIEA
GO:0004888transmembrane signaling receptor activityIEA
GO:0008144drug bindingIEA
GO:0035197siRNA bindingISS

Protein-protein interaction details for TLR7 (Homo sapiens)
(Information is obtained from BioGRID)
Not available