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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PIK3R2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0007165 signal transduction IEA GO:0007264 small GTPase mediated signal transduction TAS GO:0007596 blood coagulation TAS GO:0008286 insulin receptor signaling pathway TAS GO:0008543 fibroblast growth factor receptor signaling pathway TAS GO:0019987 negative regulation of anti-apoptosis ISS GO:0030168 platelet activation TAS GO:0031295 T cell costimulation TAS GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0048015 phosphatidylinositol-mediated signaling TAS GO:0050852 T cell receptor signaling pathway TAS GO:0050900 leukocyte migration TAS GO:0051056 regulation of small GTPase mediated signal transduction TAS cellular_component GO:0005622 intracellular IEA GO:0005829 cytosol TAS GO:0005942 phosphatidylinositol 3-kinase complex IEA molecular_function GO:0005515 protein binding IPI GO:0016303 1-phosphatidylinositol-3-kinase activity ISS GO:0035014 phosphatidylinositol 3-kinase regulator activity IEA GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS

Protein-protein interaction details for PIK3R2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ERBB3 Affinity Capture-MS physical 16729043 ERBB4 Affinity Capture-MS physical 16729043 CBL Affinity Capture-Western physical 11133830 TEC Two-hybrid physical 9178903 KIT Two-hybrid physical 10022833 AXL Biochemical Activity physical 9178760 EGF Reconstituted Complex physical 1334406 CSF1 Reconstituted Complex physical 1334406 FYN Reconstituted Complex physical 1334406 EGF Biochemical Activity physical 1334406 CSF1 Biochemical Activity physical 1334406 FYN Biochemical Activity physical 1334406 ERBB2 Reconstituted Complex physical 1334406 ERBB2 Biochemical Activity physical 1334406 PIK3CD Reconstituted Complex physical 9113989 PIK3CD Affinity Capture-Western physical 9113989 CBL Affinity Capture-Western physical 7629144 CRKL Far Western physical 9092574 CRKL Affinity Capture-Western physical 9092574 TGFBR1 Affinity Capture-Western physical 9435577 TGFBR2 Affinity Capture-Western physical 9435577 CCR5 Affinity Capture-Western physical 11350939 GRB2 Two-hybrid physical 20936779 CBL Affinity Capture-MS physical 15107835 SOCS6 Affinity Capture-MS physical 12052866 YWHAB Affinity Capture-MS physical 15324660 EGFR Affinity Capture-MS physical 19531499 ESR1 Affinity Capture-Western physical 15020686