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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PLEC (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006915 apoptosis TAS GO:0006921 cellular component disassembly involved in apoptosis TAS GO:0031581 hemidesmosome assembly IDA GO:0031581 hemidesmosome assembly TAS GO:0034329 cell junction assembly TAS cellular_component GO:0005626 insoluble fraction IEA GO:0005737 cytoplasm IDA GO:0005829 cytosol TAS GO:0005886 plasma membrane IDA GO:0005925 focal adhesion IDA GO:0030054 cell junction IEA GO:0030056 hemidesmosome IDA GO:0042383 sarcolemma IDA GO:0043292 contractile fiber IEA GO:0045111 intermediate filament cytoskeleton IDA molecular_function GO:0003779 actin binding IEA GO:0005515 protein binding IPI GO:0008307 structural constituent of muscle IMP GO:0008307 structural constituent of muscle TAS

Protein-protein interaction details for PLEC (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID GRB2 Affinity Capture-MS physical 12577067 VIM Reconstituted Complex physical 3027087 MAP2 Reconstituted Complex physical 3027087 SPTA1 Reconstituted Complex physical 3027087 SPTAN1 Reconstituted Complex physical 3027087 VIM Affinity Capture-Western physical 11441066 SPTAN1 Affinity Capture-Western physical 11441066 USP20 Affinity Capture-MS physical 19615732 PAN2 Affinity Capture-MS physical 19615732 KCTD13 Affinity Capture-MS physical 19615732 PLEKHA5 Two-hybrid physical 20936779 SRRM2 Affinity Capture-MS physical 16159877 ETS1 Affinity Capture-Western physical 20842667 TJP1 Affinity Capture-MS physical 16944923 SUMO1 Reconstituted Complex physical 19596686 UBC Affinity Capture-MS physical 21987572