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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PMAIP1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001844 protein insertion into mitochondrial membrane involved in induction of apoptosis IEA GO:0006915 apoptosis IMP GO:0006915 apoptosis TAS GO:0006917 induction of apoptosis IDA GO:0006919 activation of caspase activity IDA GO:0006921 cellular component disassembly involved in apoptosis IDA GO:0006926 virus-infected cell apoptosis IDA GO:0006974 response to DNA damage stimulus IEA GO:0008629 induction of apoptosis by intracellular signals IDA GO:0008629 induction of apoptosis by intracellular signals TAS GO:0008633 activation of pro-apoptotic gene products TAS GO:0009411 response to UV IEA GO:0010165 response to X-ray IEA GO:0010498 proteasomal protein catabolic process IDA GO:0010907 positive regulation of glucose metabolic process IDA GO:0010917 negative regulation of mitochondrial membrane potential ISS GO:0032461 positive regulation of protein oligomerization IDA GO:0042149 cellular response to glucose starvation IMP GO:0043029 T cell homeostasis ISS GO:0043065 positive regulation of apoptosis IDA GO:0043280 positive regulation of caspase activity IDA GO:0043331 response to dsRNA IDA GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator IMP GO:0043525 positive regulation of neuron apoptosis IEA GO:0046902 regulation of mitochondrial membrane permeability IDA GO:0048147 negative regulation of fibroblast proliferation IEA GO:0071456 cellular response to hypoxia IEP GO:0072332 signal transduction by p53 class mediator resulting in induction of apoptosis IMP GO:0072593 reactive oxygen species metabolic process IDA GO:0090200 positive regulation of release of cytochrome c from mitochondria IDA cellular_component GO:0005634 nucleus IDA GO:0005739 mitochondrion IDA GO:0005741 mitochondrial outer membrane TAS GO:0005829 cytosol IDA GO:0005829 cytosol TAS molecular_function GO:0005515 protein binding IPI

Protein-protein interaction details for PMAIP1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID BAX Affinity Capture-Western physical 15705586 BCL2 Protein-peptide physical 15694340 BCL2L1 Protein-peptide physical 15694340 BCL2L2 Protein-peptide physical 15694340 BCL2A1 Protein-peptide physical 15694340 MCL1 Affinity Capture-Western physical 15694340 MCL1 Affinity Capture-Western physical 15901672 ZBTB16 Two-hybrid physical 16169070 BCL2L1 Affinity Capture-Western physical 10807576 BCL2 Affinity Capture-Western physical 10807576 MCL1 Reconstituted Complex physical 21613222 HUWE1 Affinity Capture-Western physical 21907705 GSK3B Two-hybrid physical 21900206 UBC Affinity Capture-MS physical 20639865