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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for POLE (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000082G1/S transition of mitotic cell cycleIMP
GO:0000082G1/S transition of mitotic cell cycleTAS
GO:0000084S phase of mitotic cell cycleTAS
GO:0000216M/G1 transition of mitotic cell cycleTAS
GO:0000278mitotic cell cycleTAS
GO:0000722telomere maintenance via recombinationTAS
GO:0000723telomere maintenanceTAS
GO:0000731DNA synthesis involved in DNA repairIMP
GO:0001701in utero embryonic developmentIEA
GO:0006139nucleobase-containing compound metabolic processIEA
GO:0006260DNA replicationIEA
GO:0006260DNA replicationIMP
GO:0006270DNA-dependent DNA replication initiationTAS
GO:0006281DNA repairTAS
GO:0006283transcription-coupled nucleotide-excision repairTAS
GO:0006287base-excision repair, gap-fillingIDA
GO:0006289nucleotide-excision repairTAS
GO:0006297nucleotide-excision repair, DNA gap fillingIMP
GO:0006297nucleotide-excision repair, DNA gap fillingTAS
GO:0032201telomere maintenance via semi-conservative replicationTAS
cellular_component
GO:0005634nucleusIDA
GO:0005634nucleusIEA
GO:0005654nucleoplasmTAS
molecular_function
GO:0000166nucleotide bindingIEA
GO:0003676nucleic acid bindingIEA
GO:0003677DNA bindingIDA
GO:0003677DNA bindingIEA
GO:0003682chromatin bindingIDA
GO:0003887DNA-directed DNA polymerase activityIEA
GO:0003887DNA-directed DNA polymerase activityIMP
GO:0008270zinc ion bindingIEA
GO:0016740transferase activityIEA
GO:0016779nucleotidyltransferase activityIEA
GO:0046872metal ion bindingIEA

Protein-protein interaction details for POLE (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
STK19Two-hybridphysical14667819
MYCAffinity Capture-MSphysical17353931
RAD17Affinity Capture-Westernphysical14500819
RAD17Reconstituted Complexphysical14500819
TOPBP1Affinity Capture-Westernphysical11395493
PCNAAffinity Capture-MSphysical12171929
MYCAffinity Capture-MSphysical17314511
PCNAAffinity Capture-Westernphysical20227374