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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for POLE (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000082
G1/S transition of mitotic cell cycle
IMP
GO:0000082
G1/S transition of mitotic cell cycle
TAS
GO:0000084
S phase of mitotic cell cycle
TAS
GO:0000216
M/G1 transition of mitotic cell cycle
TAS
GO:0000278
mitotic cell cycle
TAS
GO:0000722
telomere maintenance via recombination
TAS
GO:0000723
telomere maintenance
TAS
GO:0000731
DNA synthesis involved in DNA repair
IMP
GO:0001701
in utero embryonic development
IEA
GO:0006139
nucleobase-containing compound metabolic process
IEA
GO:0006260
DNA replication
IEA
GO:0006260
DNA replication
IMP
GO:0006270
DNA-dependent DNA replication initiation
TAS
GO:0006281
DNA repair
TAS
GO:0006283
transcription-coupled nucleotide-excision repair
TAS
GO:0006287
base-excision repair, gap-filling
IDA
GO:0006289
nucleotide-excision repair
TAS
GO:0006297
nucleotide-excision repair, DNA gap filling
IMP
GO:0006297
nucleotide-excision repair, DNA gap filling
TAS
GO:0032201
telomere maintenance via semi-conservative replication
TAS
cellular_component
GO:0005634
nucleus
IDA
GO:0005634
nucleus
IEA
GO:0005654
nucleoplasm
TAS
molecular_function
GO:0000166
nucleotide binding
IEA
GO:0003676
nucleic acid binding
IEA
GO:0003677
DNA binding
IDA
GO:0003677
DNA binding
IEA
GO:0003682
chromatin binding
IDA
GO:0003887
DNA-directed DNA polymerase activity
IEA
GO:0003887
DNA-directed DNA polymerase activity
IMP
GO:0008270
zinc ion binding
IEA
GO:0016740
transferase activity
IEA
GO:0016779
nucleotidyltransferase activity
IEA
GO:0046872
metal ion binding
IEA
Protein-protein interaction details for POLE (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
STK19
Two-hybrid
physical
14667819
MYC
Affinity Capture-MS
physical
17353931
RAD17
Affinity Capture-Western
physical
14500819
RAD17
Reconstituted Complex
physical
14500819
TOPBP1
Affinity Capture-Western
physical
11395493
PCNA
Affinity Capture-MS
physical
12171929
MYC
Affinity Capture-MS
physical
17314511
PCNA
Affinity Capture-Western
physical
20227374