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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PPARA (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IDA GO:0001666 response to hypoxia IEA GO:0006351 transcription, DNA-dependent IDA GO:0006351 transcription, DNA-dependent ISS GO:0006355 regulation of transcription, DNA-dependent ISS GO:0006629 lipid metabolic process TAS GO:0006631 fatty acid metabolic process TAS GO:0007507 heart development IEA GO:0008544 epidermis development IEA GO:0010467 gene expression TAS GO:0010745 negative regulation of macrophage derived foam cell differentiation IC GO:0010745 negative regulation of macrophage derived foam cell differentiation IDA GO:0010871 negative regulation of receptor biosynthetic process IDA GO:0010887 negative regulation of cholesterol storage IDA GO:0010891 negative regulation of sequestering of triglyceride IDA GO:0015908 fatty acid transport TAS GO:0019217 regulation of fatty acid metabolic process IEA GO:0030522 intracellular receptor mediated signaling pathway IDA GO:0032000 positive regulation of fatty acid beta-oxidation TAS GO:0032099 negative regulation of appetite IEA GO:0032099 negative regulation of appetite ISS GO:0032868 response to insulin stimulus IEA GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor TAS GO:0042060 wound healing IEA GO:0042157 lipoprotein metabolic process IEA GO:0043401 steroid hormone mediated signaling pathway IDA GO:0044255 cellular lipid metabolic process TAS GO:0045776 negative regulation of blood pressure IEA GO:0045820 negative regulation of glycolysis IC GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0046321 positive regulation of fatty acid oxidation IEA GO:0046321 positive regulation of fatty acid oxidation ISS GO:0072363 regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter IDA GO:0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter IDA GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter IDA cellular_component GO:0005634 nucleus IEA GO:0005634 nucleus TAS GO:0005654 nucleoplasm TAS molecular_function GO:0003677 DNA binding TAS GO:0003700 sequence-specific DNA binding transcription factor activity IDA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0003700 sequence-specific DNA binding transcription factor activity ISS GO:0003706 ligand-regulated transcription factor activity IDA GO:0003706 ligand-regulated transcription factor activity IEA GO:0003707 steroid hormone receptor activity IDA GO:0003707 steroid hormone receptor activity IEA GO:0004872 receptor activity IEA GO:0004879 ligand-dependent nuclear receptor activity IDA GO:0004879 ligand-dependent nuclear receptor activity IEA GO:0005515 protein binding IPI GO:0008144 drug binding IDA GO:0008270 zinc ion binding IEA GO:0008289 lipid binding IDA GO:0008289 lipid binding IEA GO:0019904 protein domain specific binding IEA GO:0031624 ubiquitin conjugating enzyme binding IPI GO:0043565 sequence-specific DNA binding IEA GO:0043565 sequence-specific DNA binding ISS GO:0046872 metal ion binding IEA GO:0070215 MDM2 binding IEA

Protein-protein interaction details for PPARA (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID NRBF2 Two-hybrid physical 10786636 STAC3 Two-hybrid physical 16189514 GADD45G Reconstituted Complex physical 10872826 NCOA1 Two-hybrid physical 9407140 EP300 Two-hybrid physical 9407140 RXRG Two-hybrid physical 16169070 DAP3 Reconstituted Complex physical 10903152 FABP1 Two-hybrid physical 11226238 MECR Reconstituted Complex physical 9795230 RELA Reconstituted Complex physical 10542237 NRIP1 Reconstituted Complex physical 9626662 NCOA1 Reconstituted Complex physical 9626662 EP300 Two-hybrid physical 10336495 NCOR1 Two-hybrid physical 10336495 EP300 Reconstituted Complex physical 10336495 NCOR1 Reconstituted Complex physical 10336495 PPARGC1B Reconstituted Complex physical 11733490 AKAP13 Reconstituted Complex physical 9627117 POU1F1 Reconstituted Complex physical 11891224 PRIC285 Reconstituted Complex physical 12189208 RXRA Reconstituted Complex physical 10195690 NCOR2 Co-crystal Structure physical 11845213 NR1H3 Reconstituted Complex physical 8621574 PPARGC1A Reconstituted Complex physical 10669761 MED24 Reconstituted Complex physical 9653119 HSP90AA1 Affinity Capture-Western physical 12482853 HSP90AA1 Reconstituted Complex physical 12482853 AIP Affinity Capture-Western physical 12482853 AIP Reconstituted Complex physical 12482853 TRA@ Co-localization physical 19782026 SRC FRET physical 12163133 NCOR1 Affinity Capture-Western physical 15870285 NCOR1 Two-hybrid physical 18292238 LPIN1 Affinity Capture-Western physical 20385772 LPIN1 Affinity Capture-Western physical 20385772 UBE2I Reconstituted Complex physical 19955185 UBE2I Biochemical Activity physical 19955185 SUMO1 Reconstituted Complex physical 19955185 SUMO1 Affinity Capture-Western physical 19955185 SUMO1 Reconstituted Complex physical 19955185 NCOR1 Affinity Capture-Western physical 19955185 NCOR2 Affinity Capture-Western physical 19955185