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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MAP2K7 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002224 toll-like receptor signaling pathway TAS GO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS GO:0006950 response to stress IDA GO:0007165 signal transduction TAS GO:0007254 JNK cascade TAS GO:0007257 activation of JUN kinase activity ISS GO:0008063 Toll signaling pathway TAS GO:0034130 toll-like receptor 1 signaling pathway TAS GO:0034134 toll-like receptor 2 signaling pathway TAS GO:0034138 toll-like receptor 3 signaling pathway TAS GO:0034142 toll-like receptor 4 signaling pathway TAS GO:0043525 positive regulation of neuron apoptosis IEA GO:0045087 innate immune response TAS GO:0051403 stress-activated MAPK cascade IDA GO:0051403 stress-activated MAPK cascade TAS cellular_component GO:0005634 nucleus ISS GO:0005737 cytoplasm ISS GO:0005829 cytosol TAS molecular_function GO:0000166 nucleotide binding IEA GO:0000287 magnesium ion binding IDA GO:0004674 protein serine/threonine kinase activity IEA GO:0004708 MAP kinase kinase activity IDA GO:0004713 protein tyrosine kinase activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0008022 protein C-terminus binding IEA GO:0008545 JUN kinase kinase activity IEA GO:0016772 transferase activity, transferring phosphorus-containing groups IEA GO:0019901 protein kinase binding IPI GO:0019903 protein phosphatase binding ISS GO:0031435 mitogen-activated protein kinase kinase kinase binding IEA

Protein-protein interaction details for MAP2K7 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ZAK Affinity Capture-Western physical 15465036 GADD45B Affinity Capture-Western physical 14743220 GADD45B Reconstituted Complex physical 14743220 MAPK8IP1 Affinity Capture-Western physical 10490659 MAPK8IP2 Affinity Capture-Western physical 10490659 MAPK8IP1 Reconstituted Complex physical 10490659 MAPK8IP2 Reconstituted Complex physical 10490659 MAPK8IP2 Reconstituted Complex physical 10490659 DUSP19 Affinity Capture-Western physical 11959862 MAP3K5 Affinity Capture-Western physical 11959862 MAP2K4 Phenotypic Enhancement genetic 11062067 DUSP19 Reconstituted Complex physical 11959861 MAPK8IP3 Reconstituted Complex physical 10629060 MAP3K11 Biochemical Activity physical 10187804 MAP3K12 Biochemical Activity physical 10187804 MAP3K12 Affinity Capture-Western physical 10187804 MAP3K13 Biochemical Activity physical 11726277 MAPK8IP3 Affinity Capture-Western physical 12189133 MAPK14 Biochemical Activity physical 9207092 MAPK8 Biochemical Activity physical 9207092 MAPK8 Biochemical Activity physical 9207092 MAPK8 Phenotypic Enhancement genetic 9207092 MAPK8IP2 Reconstituted Complex physical 10756100 MAP3K2 Affinity Capture-Western physical 10713157 MAPK8 Affinity Capture-Western physical 10713157 MAP3K2 Co-fractionation physical 10713157 ALK Affinity Capture-MS physical 14968112 UBC Affinity Capture-Western physical 19737936