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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CBX8 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IMP GO:0006355 regulation of transcription, DNA-dependent IEA GO:0016568 chromatin modification IEA GO:0016574 histone ubiquitination IEA cellular_component GO:0000151 ubiquitin ligase complex IEA GO:0000790 nuclear chromatin IDA GO:0000792 heterochromatin IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005730 nucleolus IDA GO:0031519 PcG protein complex IDA GO:0031519 PcG protein complex IEA GO:0035102 PRC1 complex IDA molecular_function GO:0003727 single-stranded RNA binding IEA GO:0004842 ubiquitin-protein ligase activity IEA GO:0005515 protein binding IPI GO:0035064 methylated histone residue binding IDA

Protein-protein interaction details for CBX8 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID RING1 Two-hybrid physical 10825164 RING1 Affinity Capture-Western physical 10825164 HAP1 Two-hybrid physical 16169070 SETDB1 Two-hybrid physical 16169070 EEF1G Two-hybrid physical 16169070 KAT5 Two-hybrid physical 16169070 MYST2 Two-hybrid physical 16169070 UNC119 Two-hybrid physical 16169070 MLLT1 Two-hybrid physical 11313972 MLLT1 Affinity Capture-Western physical 11313972 PCGF2 Affinity Capture-MS physical 17936708 PCGF2 Affinity Capture-MS physical 19636380 BMI1 Affinity Capture-MS physical 19636380 PCGF2 Affinity Capture-Western physical 19636380 BMI1 Affinity Capture-Western physical 19636380 CENPA Co-purification physical 15009096 MLLT1 Affinity Capture-MS physical 20431927 USP7 Affinity Capture-Western physical 20601937 USP11 Affinity Capture-Western physical 20601937 BMI1 Affinity Capture-Western physical 20601937 USP7 Affinity Capture-Western physical 20601937 USP11 Affinity Capture-Western physical 20601937 CBX8 Affinity Capture-Western physical 20601937 USP7 Reconstituted Complex physical 20601937 USP11 Reconstituted Complex physical 20601937 HIST3H3 Protein-peptide physical 21047797 HIST3H3 Co-crystal Structure physical 21047797