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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for RYK (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006468 protein phosphorylation IDA GO:0007165 signal transduction TAS GO:0007411 axon guidance ISS GO:0016055 Wnt receptor signaling pathway IEA GO:0022038 corpus callosum development IEA GO:0022038 corpus callosum development ISS GO:0030182 neuron differentiation IEA GO:0030182 neuron differentiation ISS GO:0031175 neuron projection development IEA GO:0031175 neuron projection development ISS GO:0043410 positive regulation of MAPKKK cascade IDA GO:0048705 skeletal system morphogenesis IEA GO:0048843 negative regulation of axon extension involved in axon guidance IEA GO:0050919 negative chemotaxis IEA GO:0071679 commissural neuron axon guidance IEA cellular_component GO:0005624 membrane fraction IEA GO:0005634 nucleus IEA GO:0005634 nucleus ISS GO:0005737 cytoplasm IEA GO:0005737 cytoplasm ISS GO:0005886 plasma membrane IEA GO:0005887 integral to plasma membrane TAS GO:0016020 membrane ISS GO:0016021 integral to membrane NAS molecular_function GO:0000166 nucleotide binding IEA GO:0004713 protein tyrosine kinase activity IDA GO:0004713 protein tyrosine kinase activity IEA GO:0004714 transmembrane receptor protein tyrosine kinase activity IEA GO:0004872 receptor activity IEA GO:0004888 transmembrane signaling receptor activity IDA GO:0005109 frizzled binding IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016772 transferase activity, transferring phosphorus-containing groups IEA GO:0017147 Wnt-protein binding IEA

Protein-protein interaction details for RYK (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID EPHB2 Affinity Capture-Western physical 11956217 EPHB3 Affinity Capture-Western physical 11956217 CDC37 Affinity Capture-MS physical 21875946 UBC Affinity Capture-MS physical 21875946 MIB1 Affinity Capture-MS physical 21875946 PRKDC Affinity Capture-MS physical 21875946 GPR125 Affinity Capture-MS physical 21875946 DSG2 Affinity Capture-MS physical 21875946 CELSR2 Affinity Capture-MS physical 21875946 DSC3 Affinity Capture-MS physical 21875946 PTK7 Affinity Capture-MS physical 21875946 CD276 Affinity Capture-MS physical 21875946 DKFZp686O24166 Affinity Capture-MS physical 21875946 CELSR1 Affinity Capture-MS physical 21875946 FREM2 Affinity Capture-MS physical 21875946 TP53 Affinity Capture-MS physical 21875946 CNNM3 Affinity Capture-MS physical 21875946 VIM Affinity Capture-MS physical 21875946 MAPK1 Affinity Capture-MS physical 21875946 PCNA Affinity Capture-MS physical 21875946 NCKAP1 Affinity Capture-MS physical 21875946 AGK Affinity Capture-MS physical 21875946 AIFM1 Affinity Capture-MS physical 21875946 CNNM2 Affinity Capture-MS physical 21875946 GPR124 Affinity Capture-MS physical 21875946 FAT4 Affinity Capture-MS physical 21875946 CDHR1 Affinity Capture-MS physical 21875946 WASF2 Affinity Capture-MS physical 21875946 CTNNA1 Affinity Capture-MS physical 21875946 DCHS1 Affinity Capture-MS physical 21875946 NOMO3 Affinity Capture-MS physical 21875946 NPEPPS Affinity Capture-MS physical 21875946 PCDH9 Affinity Capture-MS physical 21875946 ABI1 Affinity Capture-MS physical 21875946 APLP2 Affinity Capture-MS physical 21875946 MAPK3 Affinity Capture-MS physical 21875946 CYFIP1 Affinity Capture-MS physical 21875946 ITM2B Affinity Capture-MS physical 21875946 PTPRS Affinity Capture-MS physical 21875946 ITM2C Affinity Capture-MS physical 21875946 NRP2 Affinity Capture-MS physical 21875946 PTPRF Affinity Capture-MS physical 21875946 TMED10 Affinity Capture-MS physical 21875946 DYNC1H1 Affinity Capture-MS physical 21875946 PCDH7 Affinity Capture-MS physical 21875946 PCDH20 Affinity Capture-MS physical 21875946 TFRC Affinity Capture-MS physical 21875946 PCDHGA11 Affinity Capture-MS physical 21875946 PARP1 Affinity Capture-MS physical 21875946 TMEM59 Affinity Capture-MS physical 21875946 VPS26A Affinity Capture-MS physical 21875946 WASF1 Affinity Capture-MS physical 21875946 WASF3 Affinity Capture-MS physical 21875946 CDK1 Affinity Capture-MS physical 21875946 DSC2 Affinity Capture-MS physical 21875946 NPM1 Affinity Capture-MS physical 21875946 TRAP1 Affinity Capture-MS physical 21875946 CDH2 Affinity Capture-MS physical 21875946 VPS35 Affinity Capture-MS physical 21875946 CTNNB1 Affinity Capture-MS physical 21875946 NUP93 Affinity Capture-MS physical 21875946 EPHA4 Affinity Capture-MS physical 21875946 RHOT2 Affinity Capture-MS physical 21875946 ST13 Affinity Capture-MS physical 21875946 CELSR3 Affinity Capture-MS physical 21875946 FAT3 Affinity Capture-MS physical 21875946 OSGEP Affinity Capture-MS physical 21875946 TIMM50 Affinity Capture-MS physical 21875946 MIB1 Affinity Capture-Western physical 21875946 MIB1 Affinity Capture-Western physical 21875946 UBC Affinity Capture-Western physical 21875946