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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SKP1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000082 G1/S transition of mitotic cell cycle TAS GO:0000084 S phase of mitotic cell cycle TAS GO:0000278 mitotic cell cycle TAS GO:0006511 ubiquitin-dependent protein catabolic process IEA GO:0016032 viral reproduction TAS GO:0016567 protein ubiquitination IDA GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process TAS GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IDA GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IEA GO:0035518 histone H2A monoubiquitination IDA GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS cellular_component GO:0005654 nucleoplasm TAS GO:0005829 cytosol IEA GO:0005829 cytosol TAS GO:0019005 SCF ubiquitin ligase complex IDA GO:0019005 SCF ubiquitin ligase complex IEA GO:0031519 PcG protein complex IDA molecular_function GO:0004842 ubiquitin-protein ligase activity IDA GO:0005515 protein binding IPI

Protein-protein interaction details for SKP1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID CACYBP Two-hybrid physical 11389839 FBXO4 Affinity Capture-MS physical 17353931 TBK1 Affinity Capture-MS physical 14743216 SUGT1 Reconstituted Complex physical 12746458 CDCA3 Reconstituted Complex physical 12679038 CDCA3 Affinity Capture-Western physical 12679038 FBXW7 Affinity Capture-Western physical 12628165 CUL1 Affinity Capture-Western physical 12628165 RBX1 Affinity Capture-Western physical 12628165 CUL1 Affinity Capture-Western physical 12609982 BTRC Affinity Capture-Western physical 12609982 SKP2 Affinity Capture-Western physical 12609982 FBXO34 Two-hybrid physical 16169070 FBXO34 Two-hybrid physical 16169070 FBXW7 Affinity Capture-Western physical 11585921 FBXW7 Affinity Capture-Western physical 11585921 FBXW7 Reconstituted Complex physical 11585921 FBXL4 Reconstituted Complex physical 10531037 FBXL5 Reconstituted Complex physical 10531037 FBXW11 Affinity Capture-Western physical 10644755 BTRC Affinity Capture-Western physical 10644755 CDK9 Reconstituted Complex physical 11689688 CDK9 Affinity Capture-Western physical 11689688 CUL7 Affinity Capture-Western physical 12481031 FBXW8 Affinity Capture-Western physical 12481031 CUL1 Affinity Capture-Western physical 9430629 BTRC Reconstituted Complex physical 10918611 SKP2 Reconstituted Complex physical 10918611 FBXO32 Reconstituted Complex physical 11717410 SKP2 Reconstituted Complex physical 9827542 SKP2 Two-hybrid physical 9827542 CACYBP Reconstituted Complex physical 11389839 CACYBP Affinity Capture-Western physical 11389839 TBL1X Affinity Capture-Western physical 11389839 CTNNB1 Affinity Capture-Western physical 11389839 BTRC Two-hybrid physical 9660940 SKP2 Co-crystal Structure physical 11099048 BTRC Affinity Capture-Western physical 10531035 FBXO4 Affinity Capture-Western physical 10531035 FBXO7 Affinity Capture-Western physical 10531035 FBXW2 Affinity Capture-Western physical 10531035 FBXL3 Affinity Capture-Western physical 10531035 BTRC Two-hybrid physical 10531035 FBXW2 Two-hybrid physical 10531035 FBXO4 Two-hybrid physical 10531035 FBXO5 Two-hybrid physical 10531035 FBXO7 Two-hybrid physical 10531035 FBXL3 Two-hybrid physical 10531035 BTRC Reconstituted Complex physical 10531035 FBXW2 Reconstituted Complex physical 10531035 FBXL3 Reconstituted Complex physical 10531035 FBXO4 Reconstituted Complex physical 10531035 FBXO5 Reconstituted Complex physical 10531035 FBXO7 Reconstituted Complex physical 10531035 SKP2 Reconstituted Complex physical 10531035 FBXO44 Reconstituted Complex physical 10531035 FBXO44 Two-hybrid physical 10531035 FBXO18 Two-hybrid physical 11956208 FBXO18 Affinity Capture-Western physical 11956208 FBXO18 Affinity Capture-Western physical 11956208 SKP2 Reconstituted Complex physical 10559858 CUL1 Co-crystal Structure physical 11961546 CUL1 Two-hybrid physical 10230407 ETV6 Affinity Capture-Western physical 18426905 C13orf34 Affinity Capture-Western physical 18378770 FBXW11 Affinity Capture-MS physical 19615732 FBXW7 Co-crystal Structure physical 17434132 ZC3HC1 Affinity Capture-Western physical 17389604 FBXO2 Co-crystal Structure physical 17389369 FBXO11 Affinity Capture-Western physical 17098746 BCOR Affinity Capture-MS physical 16943429 PCGF1 Affinity Capture-MS physical 16943429 KDM2B Reconstituted Complex physical 16943429 SKP2 Affinity Capture-MS physical 16880511 TRIM21 Affinity Capture-Western physical 16880511 TRIM21 Co-fractionation physical 16880511 CUL1 Affinity Capture-Western physical 16759355 FBXO31 Affinity Capture-Western physical 16357137 CUL1 Affinity Capture-Western physical 16357137 FBXO31 Affinity Capture-Western physical 16357137 RBX1 Affinity Capture-Western physical 16357137 ZC3HC1 Reconstituted Complex physical 16009132 ZC3HC1 Affinity Capture-Western physical 16009132 ZC3HC1 Reconstituted Complex physical 16009132 CUL1 Affinity Capture-Western physical 15966899 GCM1 Affinity Capture-Western physical 15640526 SKP2 Affinity Capture-Western physical 15469821 SKP2 Reconstituted Complex physical 15452136 CUL1 Reconstituted Complex physical 15452136 RBX1 Reconstituted Complex physical 15452136 SKP2 Two-hybrid physical 15342634 FBXO7 Affinity Capture-Western physical 15145941 FBXO18 Reconstituted Complex physical 15118074 BTRC Affinity Capture-Western physical 15070733 FBXW11 Affinity Capture-Western physical 15070733 SKP2 Affinity Capture-Western physical 15070733 BTRC Co-crystal Structure physical 12820959 RBL2 Affinity Capture-Western physical 12717421 SNRNP70 Affinity Capture-Western physical 11850407 BTRC Affinity Capture-Western physical 11483504 RBX1 Reconstituted Complex physical 11245432 CUL1 Affinity Capture-Western physical 10713156 CUL1 Affinity Capture-Western physical 10648623 BTRC Affinity Capture-Western physical 10514433 BTRC Affinity Capture-Western physical 10514433 BTRC Two-hybrid physical 10514433 NFKBIA Affinity Capture-Western physical 10514433 FBXW11 Affinity Capture-Western physical 10321728 CUL1 Co-fractionation physical 10230406 NFKBIA Reconstituted Complex physical 10230406 FBXW11 Affinity Capture-Western physical 10230406 BTRC Affinity Capture-Western physical 10228155 NFKBIA Affinity Capture-Western physical 10066435 RASSF1 Affinity Capture-Western physical 18071316 CCND1 Affinity Capture-Western physical 17205132 FBXW8 Affinity Capture-Western physical 17205132 CUL1 Reconstituted Complex physical 21778237 FBXW11 Reconstituted Complex physical 12165731 FBXO4 Affinity Capture-Western physical 17081987 CCND1 Affinity Capture-Western physical 17081987 FBXO4 Reconstituted Complex physical 20181953 FBXO4 Co-crystal Structure physical 20181953 TERF1 Reconstituted Complex physical 20181953 UBC Affinity Capture-MS physical 16196087 CTNNB1 Biochemical Activity physical 20181957 FBXW11 Biochemical Activity physical 12165731 TERF1 Biochemical Activity physical 20181953 MYC Affinity Capture-MS physical 17314511 FBXO7 Reconstituted Complex physical 21378169 BTRC Two-hybrid physical 10074433 SKP2 Affinity Capture-Western physical 19270694 CUL1 Affinity Capture-Western physical 19270694 SKP2 Affinity Capture-Western physical 19270694 SKP2 Reconstituted Complex physical 19270694 UBXN7 Affinity Capture-MS physical 18775313 FAF1 Affinity Capture-MS physical 18775313 FBXO8 Affinity Capture-Western physical 18094045 CUL1 Affinity Capture-Western physical 18094045 UHRF2 Far Western physical 21952639 CUL1 Affinity Capture-Western physical 19933270 BTRC Affinity Capture-Western physical 19933270 FBXL5 Affinity Capture-Western physical 19762596 FBXO42 Affinity Capture-Western physical 19509332 SKP2 Affinity Capture-Western physical 20041211 FBXW7 Affinity Capture-Western physical 21620836 CUL1 Affinity Capture-Western physical 20832730 FBXO11 Affinity Capture-Western physical 22113614 ZC3HC1 Affinity Capture-Western physical 22205987 UBC Affinity Capture-MS physical 18781797 FBXW8 Affinity Capture-MS physical 21572988 CUL1 Affinity Capture-Western physical 21249194 PCK1 Affinity Capture-MS physical 21726808