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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SOS2 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006915apoptosisTAS
GO:0007264small GTPase mediated signal transductionNAS
GO:0007264small GTPase mediated signal transductionTAS
GO:0007411axon guidanceTAS
GO:0008624induction of apoptosis by extracellular signalsTAS
GO:0035023regulation of Rho protein signal transductionIEA
GO:0048011nerve growth factor receptor signaling pathwayTAS
GO:0051056regulation of small GTPase mediated signal transductionIEA
GO:0051056regulation of small GTPase mediated signal transductionTAS
cellular_component
GO:0005622intracellularIEA
GO:0005829cytosolTAS
molecular_function
GO:0003677DNA bindingIEA
GO:0005085guanyl-nucleotide exchange factor activityIEA
GO:0005085guanyl-nucleotide exchange factor activityNAS
GO:0005089Rho guanyl-nucleotide exchange factor activityIEA
GO:0005515protein bindingIPI

Protein-protein interaction details for SOS2 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
GRAP2Reconstituted Complexphysical10820259
SHC1Affinity Capture-Westernphysical10675333
EGFRAffinity Capture-Westernphysical10675333
PLCG1Two-hybridphysical10940929
PLCG1Affinity Capture-Westernphysical10940929
GRB2Affinity Capture-Westernphysical10940929
GRB2Two-hybridphysical7629138
GRB2Two-hybridphysical20936779
EGFRAffinity Capture-MSphysical19531499
ESR1Affinity Capture-Westernphysical15173068