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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SP100 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IDA GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator IDA GO:0019221 cytokine-mediated signaling pathway TAS GO:0032526 response to retinoic acid IDA GO:0032897 negative regulation of viral transcription IDA GO:0034097 response to cytokine stimulus IDA GO:0034340 response to type I interferon IDA GO:0034340 response to type I interferon IMP GO:0034341 response to interferon-gamma IDA GO:0034341 response to interferon-gamma IMP GO:0043392 negative regulation of DNA binding IDA GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity IDA GO:0044419 interspecies interaction between organisms IEA GO:0045892 negative regulation of transcription, DNA-dependent IDA GO:0045892 negative regulation of transcription, DNA-dependent IMP GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045893 positive regulation of transcription, DNA-dependent IMP GO:0048384 retinoic acid receptor signaling pathway IC GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity IDA GO:0051271 negative regulation of cellular component movement IMP GO:0060333 interferon-gamma-mediated signaling pathway IC GO:0060333 interferon-gamma-mediated signaling pathway TAS GO:0060337 type I interferon-mediated signaling pathway IC cellular_component GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005730 nucleolus IDA GO:0005730 nucleolus IMP GO:0005737 cytoplasm IDA GO:0016605 PML body IDA GO:0034399 nuclear periphery IDA molecular_function GO:0003677 DNA binding IEA GO:0003713 transcription coactivator activity IDA GO:0003714 transcription corepressor activity IDA GO:0005488 binding IEA GO:0005515 protein binding IPI GO:0008134 transcription factor binding IPI GO:0008270 zinc ion binding IEA GO:0019900 kinase binding IPI GO:0019904 protein domain specific binding IPI GO:0042802 identical protein binding IPI GO:0042803 protein homodimerization activity IPI GO:0046872 metal ion binding IEA GO:0070087 chromo shadow domain binding IPI

Protein-protein interaction details for SP100 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SUMO1 Two-hybrid physical 16189514 HIPK2 Affinity Capture-Western physical 14647468 CBX3 Affinity Capture-Western physical 9636147 CBX3 Reconstituted Complex physical 9636147 CBX3 Two-hybrid physical 9636147 UBE2I Biochemical Activity physical 18691969 UBE2I Reconstituted Complex physical 18691969 SAE1 Biochemical Activity physical 11792325 UBA2 Biochemical Activity physical 11792325 MX1 Two-hybrid physical 11716541 CBX5 Two-hybrid physical 9636146 CBX3 Two-hybrid physical 9636146 CBX1 Two-hybrid physical 9636146 CBX5 Reconstituted Complex physical 9636146 CBX5 Reconstituted Complex physical 11313457 UBE2I Two-hybrid physical 20936779 MYB Two-hybrid physical 20211142 LZTR1 Two-hybrid physical 20211142 TRIM29 Two-hybrid physical 20211142 CBX5 Protein-peptide physical 15882967 CBX5 Protein-peptide physical 15882967 CBX5 Affinity Capture-Western physical 15882967 NIPBL Reconstituted Complex physical 15882967 PML Co-localization physical 21779164 PML Co-localization physical 21779164 PML Co-localization physical 21172801