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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for STK11 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001558 regulation of cell growth ISS GO:0001894 tissue homeostasis IEA GO:0001934 positive regulation of protein phosphorylation IDA GO:0001944 vasculature development ISS GO:0006112 energy reserve metabolic process TAS GO:0006468 protein phosphorylation IDA GO:0006914 autophagy IEA GO:0006974 response to DNA damage stimulus IEA GO:0007049 cell cycle IEA GO:0007050 cell cycle arrest IDA GO:0007050 cell cycle arrest TAS GO:0008285 negative regulation of cell proliferation IMP GO:0008286 insulin receptor signaling pathway TAS GO:0010212 response to ionizing radiation ISS GO:0030010 establishment of cell polarity ISS GO:0030111 regulation of Wnt receptor signaling pathway IEA GO:0030308 negative regulation of cell growth ISS GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway IMP GO:0033762 response to glucagon stimulus IEA GO:0033993 response to lipid IEA GO:0042304 regulation of fatty acid biosynthetic process TAS GO:0042593 glucose homeostasis ISS GO:0043276 anoikis IMP GO:0045722 positive regulation of gluconeogenesis IEA GO:0046320 regulation of fatty acid oxidation TAS GO:0046777 protein autophosphorylation IDA GO:0050772 positive regulation of axonogenesis IEA GO:0051291 protein heterooligomerization IEA GO:0051645 Golgi localization IEA GO:0051896 regulation of protein kinase B signaling cascade IEA GO:0060070 canonical Wnt receptor signaling pathway IEA GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development IEA GO:0072332 signal transduction by p53 class mediator resulting in induction of apoptosis IDA cellular_component GO:0005634 nucleus IDA GO:0005737 cytoplasm IDA GO:0005739 mitochondrion IDA GO:0005829 cytosol ISS GO:0005829 cytosol TAS GO:0016020 membrane ISS GO:0043234 protein complex IEA molecular_function GO:0000166 nucleotide binding IEA GO:0000287 magnesium ion binding IDA GO:0002039 p53 binding IDA GO:0004674 protein serine/threonine kinase activity IDA GO:0004674 protein serine/threonine kinase activity TAS GO:0005515 protein binding IPI GO:0005524 ATP binding IDA GO:0030275 LRR domain binding IEA GO:0030295 protein kinase activator activity IDA

Protein-protein interaction details for STK11 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID CAB39 Affinity Capture-Western physical 15561763 STRADA Affinity Capture-Western physical 15561763 STRADA Affinity Capture-Western physical 12805220 STRADA Reconstituted Complex physical 12805220 STRADA Biochemical Activity physical 12805220 STRADA Two-hybrid physical 12805220 SMARCA4 Reconstituted Complex physical 11445556 SMARCA4 Affinity Capture-Western physical 11445556 STK11IP Affinity Capture-Western physical 11741830 HSP90AA1 Affinity Capture-Western physical 12489981 CDC37 Affinity Capture-Western physical 12489981 HSP90AA1 Reconstituted Complex physical 12489981 CDC37 Reconstituted Complex physical 12489981 TP53 Affinity Capture-Western physical 11430832 WDR48 Affinity Capture-MS physical 19615732 CAB39 Affinity Capture-MS physical 20562859 STRADA Affinity Capture-MS physical 20562859 FKBP5 Affinity Capture-MS physical 20562859 STRADB Affinity Capture-MS physical 20562859 CAB39L Affinity Capture-MS physical 20562859 CDC37 Affinity Capture-MS physical 20562859 HSP90AA1 Affinity Capture-Western physical 14668798 CDC37 Affinity Capture-Western physical 14668798 UBC Affinity Capture-Western physical 14668798 STRADB Biochemical Activity physical 14676191 MARK4 Affinity Capture-Western physical 14676191 CAB39 Affinity Capture-MS physical 14676191 HSP90AA1 Affinity Capture-MS physical 14676191 STRADA Affinity Capture-MS physical 14676191 CDC37 Affinity Capture-MS physical 14676191 HSPA1A Affinity Capture-MS physical 14676191 FKBP5 Affinity Capture-MS physical 14676191 STRADB Affinity Capture-MS physical 14676191 RPAP3 Affinity Capture-MS physical 14676191 USP11 Affinity Capture-MS physical 14676191 LIMS1 Affinity Capture-MS physical 14676191 KIF23 Affinity Capture-MS physical 14676191 SMARCC1 Affinity Capture-MS physical 14676191 SMARCA4 Affinity Capture-MS physical 14676191