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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TAP2 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001916positive regulation of T cell mediated cytotoxicityIBA
GO:0002474antigen processing and presentation of peptide antigen via MHC class ITAS
GO:0002481antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependentIBA
GO:0002485antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependentIBA
GO:0002489antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependentIBA
GO:0002489antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependentIMP
GO:0002504antigen processing and presentation of peptide or polysaccharide antigen via MHC class IIIEA
GO:0002591positive regulation of antigen processing and presentation of peptide antigen via MHC class IIBA
GO:0006955immune responseIEA
GO:0015031protein transportIEA
GO:0015833peptide transportIBA
GO:0015833peptide transportIGI
GO:0019060intracellular transport of viral proteins in host cellIMP
GO:0019882antigen processing and presentationIEA
GO:0019885antigen processing and presentation of endogenous peptide antigen via MHC class IIDA
GO:0019885antigen processing and presentation of endogenous peptide antigen via MHC class IIMP
GO:0044419interspecies interaction between organismsIEA
GO:0046967cytosol to ER transportIMP
GO:0046968peptide antigen transportIDA
GO:0046968peptide antigen transportIMP
GO:0055085transmembrane transportIBA
GO:0055085transmembrane transportIEA
cellular_component
GO:0005634nucleusIDA
GO:0005743mitochondrial inner membraneIRD
GO:0005783endoplasmic reticulumIDA
GO:0005789endoplasmic reticulum membraneTAS
GO:0005886plasma membraneIBA
GO:0016020membraneIEA
GO:0016021integral to membraneIDA
GO:0016021integral to membraneIEA
GO:0030176integral to endoplasmic reticulum membraneIDA
GO:0042613MHC class II protein complexIEA
GO:0042825TAP complexIBA
GO:0042825TAP complexIDA
molecular_function
GO:0000166nucleotide bindingIEA
GO:0005215transporter activityIDA
GO:0005215transporter activityIEA
GO:0005515protein bindingIPI
GO:0005524ATP bindingIDA
GO:0005524ATP bindingIEA
GO:0015197peptide transporter activityIEA
GO:0015197peptide transporter activityIGI
GO:0015421oligopeptide-transporting ATPase activityIBA
GO:0015433peptide antigen-transporting ATPase activityIMP
GO:0016887ATPase activityIEA
GO:0042288MHC class I protein bindingIBA
GO:0042605peptide antigen bindingIBA
GO:0042626ATPase activity, coupled to transmembrane movement of substancesIEA
GO:0046978TAP1 bindingIBA
GO:0046978TAP1 bindingIPI
GO:0046979TAP2 bindingIBA
GO:0046980tapasin bindingIBA

Protein-protein interaction details for TAP2 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
HLA-GAffinity Capture-Westernphysical9103419
TAP1Reconstituted Complexphysical11381133
TAPBPReconstituted Complexphysical12213826
HLA-CAffinity Capture-Westernphysical9551969
UBCAffinity Capture-MSphysical21987572