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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for THRA (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006357 regulation of transcription from RNA polymerase II promoter IDA GO:0006366 transcription from RNA polymerase II promoter IDA GO:0009755 hormone-mediated signaling pathway IDA GO:0010467 gene expression TAS GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly IDA GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor TAS GO:0045892 negative regulation of transcription, DNA-dependent IDA GO:2000143 negative regulation of transcription initiation, DNA-dependent IDA cellular_component GO:0005634 nucleus IDA GO:0005654 nucleoplasm TAS GO:0005829 cytosol IDA molecular_function GO:0003700 sequence-specific DNA binding transcription factor activity IDA GO:0003707 steroid hormone receptor activity IEA GO:0004872 receptor activity IEA GO:0004887 thyroid hormone receptor activity IDA GO:0005515 protein binding IPI GO:0008134 transcription factor binding IPI GO:0008270 zinc ion binding IEA GO:0017025 TBP-class protein binding IDA GO:0019904 protein domain specific binding IPI GO:0043565 sequence-specific DNA binding IEA GO:0044212 transcription regulatory region DNA binding IDA GO:0046872 metal ion binding IEA GO:0070324 thyroid hormone binding IDA GO:0070324 thyroid hormone binding IPI

Protein-protein interaction details for THRA (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID NCOA6 Reconstituted Complex physical 10567404 NCOA6 Two-hybrid physical 10567404 NCOA6 Affinity Capture-Western physical 10847592 TDG Reconstituted Complex physical 12874288 CCND1 Affinity Capture-Western physical 12048199 MEF2A Reconstituted Complex physical 12371907 MEF2A Affinity Capture-Western physical 12371907 EP300 Affinity Capture-Western physical 12371907 MEF2A Affinity Capture-Western physical 12371907 EP300 Affinity Capture-Western physical 12371907 YWHAQ Reconstituted Complex physical 11266503 ITGB3BP Reconstituted Complex physical 11713274 ITGB3BP Two-hybrid physical 11713274 ITGB3BP Two-hybrid physical 11713274 POU2F1 Reconstituted Complex physical 10480874 DAP3 Reconstituted Complex physical 10903152 NR0B2 Reconstituted Complex physical 8650544 NRIP1 Reconstituted Complex physical 9626662 HR Affinity Capture-Western physical 11641275 AKAP13 Reconstituted Complex physical 9627117 MED12 Affinity Capture-MS physical 10198638 MED16 Affinity Capture-MS physical 10198638 MED6 Affinity Capture-MS physical 10198638 MED12 Affinity Capture-Western physical 10198638 MED24 Affinity Capture-Western physical 10198638 MED16 Affinity Capture-Western physical 10198638 CDK8 Affinity Capture-Western physical 10198638 MED21 Affinity Capture-Western physical 10198638 MED6 Affinity Capture-Western physical 10198638 TRIM24 Reconstituted Complex physical 9115274 COPS2 Two-hybrid physical 10207062 COPS2 Reconstituted Complex physical 10207062 COPS2 Reconstituted Complex physical 10207062 TRIP11 Affinity Capture-Western physical 9256431 TRIP11 Reconstituted Complex physical 9256431 ITGB3BP Two-hybrid physical 10490654 ITGB3BP Reconstituted Complex physical 10490654 RXRA Co-purification physical 1314167 MED1 Far Western physical 9653119 MED1 Reconstituted Complex physical 9653119 FUS Reconstituted Complex physical 9440806 UBC Affinity Capture-MS physical 18655026 UBC Affinity Capture-Western physical 18655026 HDAC3 Affinity Capture-Western physical 11889044 NCOR1 Affinity Capture-Western physical 11889044 ZBTB3 Two-hybrid physical 20211142 SUV39H1 Reconstituted Complex physical 12138181 PARP1 Affinity Capture-Western physical 15808511 NCOA1 Affinity Capture-Western physical 11117530 NCOA2 Affinity Capture-Western physical 11117530 NCOA3 Affinity Capture-Western physical 11117530 MED1 Affinity Capture-Western physical 11117530 MED24 Affinity Capture-Western physical 11117530 RXRA Affinity Capture-Western physical 11117530 COPS2 Reconstituted Complex physical 10877839 TAF11 Two-hybrid physical 10744685 TAF11 Affinity Capture-Western physical 10744685 TAF11 Affinity Capture-Western physical 10744685 MED1 Reconstituted Complex physical 10733574 MED1 Reconstituted Complex physical 10733574 TAF7 Affinity Capture-Western physical 10409738 TAF7 Affinity Capture-Western physical 10409738 SRC Reconstituted Complex physical 15140878 NRIP1 Reconstituted Complex physical 15130509 NCOR1 Reconstituted Complex physical 15131262 GRIP1 Reconstituted Complex physical 10379889 NCOA1 Reconstituted Complex physical 10379889 NRIP1 Reconstituted Complex physical 10379889 MED1 Reconstituted Complex physical 10037764 NCOR1 Reconstituted Complex physical 9849963 GRIP1 Reconstituted Complex physical 9849963 NCOR1 Two-hybrid physical 9849963 NCOA1 Two-hybrid physical 9849963 GRIP1 Two-hybrid physical 9849963 NCOR1 Reconstituted Complex physical 9804773 NCOA1 Reconstituted Complex physical 9804773 NCOR2 Far Western physical 9415406 EMD Affinity Capture-MS physical 17620012 PRKDC Affinity Capture-MS physical 17242407 NCOR1 Affinity Capture-MS physical 17242407 NCOR2 Affinity Capture-MS physical 17242407 SMC1A Affinity Capture-MS physical 17242407 PARP1 Affinity Capture-MS physical 17242407 LIG3 Affinity Capture-MS physical 17242407 XRCC5 Affinity Capture-MS physical 17242407 XRCC6 Affinity Capture-MS physical 17242407 HSPA4 Affinity Capture-MS physical 17242407 TBL1XR1 Affinity Capture-MS physical 17242407 HDAC3 Affinity Capture-MS physical 17242407 GPS2 Affinity Capture-MS physical 17242407 PRKDC Reconstituted Complex physical 17242407 NCOR1 Reconstituted Complex physical 17242407 HDAC3 Reconstituted Complex physical 17242407 TBL1X Reconstituted Complex physical 17242407 RXRA Two-hybrid physical 15604093 CUL1 Two-hybrid physical 15604093 RGN Two-hybrid physical 15604093 SEPP1 Two-hybrid physical 15604093 NCOR1 Two-hybrid physical 15604093 MED1 Reconstituted Complex physical 16799563 MED21 Two-hybrid physical 15249124 CDK7 Two-hybrid physical 15249124 MED21 Reconstituted Complex physical 15249124 MED25 Two-hybrid physical 17641689